Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0450c and Rv0451c overlap by 4 nucleotides Rv0451c and Rv0452 are separated by 231 nucleotides
Rv0450c: Rv0450c - Probable conserved transmembrane transport protein MmpL4, at 538,588 to 541,491
Rv0450c
Rv0451c: Rv0451c - Probable conserved membrane protein MmpS4, at 541,488 to 541,910
Rv0451c
Rv0452: Rv0452 - Possible transcriptional regulatory protein, at 542,142 to 542,852
Rv0452
Position (kb) 541
542 Strain fitness (log2 ratio) -2
-1
0
1 at 540.513 kb on - strand, within Rv0450c at 540.597 kb on - strand, within Rv0450c at 540.605 kb on + strand, within Rv0450c at 540.605 kb on + strand, within Rv0450c at 540.606 kb on - strand, within Rv0450c at 540.609 kb on - strand, within Rv0450c at 540.674 kb on + strand, within Rv0450c at 540.675 kb on - strand, within Rv0450c at 540.748 kb on - strand, within Rv0450c at 540.900 kb on + strand, within Rv0450c at 541.510 kb on + strand at 541.644 kb on - strand, within Rv0451c at 541.801 kb on + strand, within Rv0451c at 541.905 kb on + strand at 541.906 kb on - strand at 541.906 kb on - strand at 541.906 kb on - strand at 541.995 kb on + strand at 541.995 kb on + strand at 542.009 kb on + strand at 542.038 kb on - strand at 542.038 kb on - strand at 542.059 kb on + strand at 542.059 kb on + strand at 542.060 kb on - strand at 542.079 kb on - strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.107 kb on + strand at 542.108 kb on - strand at 542.399 kb on - strand, within Rv0452 at 542.582 kb on - strand, within Rv0452 at 542.658 kb on + strand, within Rv0452 at 542.719 kb on - strand, within Rv0452
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 540,513 - Rv0450c 0.66 +1.2 540,597 - Rv0450c 0.69 -1.2 540,605 + Rv0450c 0.69 -0.5 540,605 + Rv0450c 0.69 -0.8 540,606 - Rv0450c 0.69 -0.9 540,609 - Rv0450c 0.70 -0.7 540,674 + Rv0450c 0.72 -0.8 540,675 - Rv0450c 0.72 -1.7 540,748 - Rv0450c 0.74 +0.5 540,900 + Rv0450c 0.80 -0.8 541,510 + -0.4 541,644 - Rv0451c 0.37 +1.3 541,801 + Rv0451c 0.74 -1.2 541,905 + -1.6 541,906 - +0.0 541,906 - -0.1 541,906 - +0.0 541,995 + -1.4 541,995 + -0.2 542,009 + +0.9 542,038 - +0.0 542,038 - +0.9 542,059 + +0.5 542,059 + -0.4 542,060 - +0.1 542,079 - -1.2 542,107 + -0.1 542,107 + +0.4 542,107 + -0.3 542,107 + +0.7 542,107 + -0.6 542,107 + +0.9 542,107 + -0.2 542,108 - -0.3 542,399 - Rv0452 0.36 -0.9 542,582 - Rv0452 0.62 -0.4 542,658 + Rv0452 0.73 -0.6 542,719 - Rv0452 0.81 -2.4
Or see this region's nucleotide sequence