Experiment: 7H9 with Delamanid 0.236 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0132c and Rv0133 are separated by 86 nucleotides Rv0133 and Rv0134 are separated by 296 nucleotides
Rv0132c: Rv0132c - Putative F420-dependent glucose-6-phosphate dehydrogenase Fgd2, at 159,700 to 160,782
Rv0132c
Rv0133: Rv0133 - GCN5-related N-acetyltransferase, at 160,869 to 161,474
Rv0133
Rv0134: Rv0134 - Possible epoxide hydrolase EphF (epoxide hydratase) (arene-oxide hydratase), at 161,771 to 162,673
Rv0134
Position (kb) 160
161
162 Strain fitness (log2 ratio) -2
-1
0
1
2
3 at 160.264 kb on + strand, within Rv0132c at 160.264 kb on + strand, within Rv0132c at 160.265 kb on - strand, within Rv0132c at 160.265 kb on - strand, within Rv0132c at 160.265 kb on - strand, within Rv0132c at 160.302 kb on - strand, within Rv0132c at 160.302 kb on - strand, within Rv0132c at 160.427 kb on + strand, within Rv0132c at 160.433 kb on + strand, within Rv0132c at 160.433 kb on + strand, within Rv0132c at 160.433 kb on + strand, within Rv0132c at 160.434 kb on - strand, within Rv0132c at 160.434 kb on - strand, within Rv0132c at 160.434 kb on - strand, within Rv0132c at 160.434 kb on - strand, within Rv0132c at 160.436 kb on - strand, within Rv0132c at 160.546 kb on + strand, within Rv0132c at 160.546 kb on + strand, within Rv0132c at 160.547 kb on - strand, within Rv0132c at 160.547 kb on - strand, within Rv0132c at 160.568 kb on + strand, within Rv0132c at 160.569 kb on - strand, within Rv0132c at 160.941 kb on + strand, within Rv0133 at 160.941 kb on + strand, within Rv0133 at 160.966 kb on + strand, within Rv0133 at 160.967 kb on - strand, within Rv0133 at 161.245 kb on - strand, within Rv0133 at 161.245 kb on - strand, within Rv0133 at 161.245 kb on - strand, within Rv0133 at 161.349 kb on + strand, within Rv0133 at 161.385 kb on + strand, within Rv0133 at 161.386 kb on - strand, within Rv0133 at 161.386 kb on - strand, within Rv0133 at 161.386 kb on - strand, within Rv0133 at 161.446 kb on + strand at 161.607 kb on + strand at 161.608 kb on - strand at 161.702 kb on - strand at 161.702 kb on - strand at 161.702 kb on - strand at 161.702 kb on - strand at 161.756 kb on + strand at 161.756 kb on + strand at 161.756 kb on + strand at 161.878 kb on - strand, within Rv0134 at 162.011 kb on + strand, within Rv0134 at 162.013 kb on + strand, within Rv0134 at 162.013 kb on + strand, within Rv0134 at 162.013 kb on + strand, within Rv0134 at 162.013 kb on + strand, within Rv0134 at 162.014 kb on - strand, within Rv0134 at 162.211 kb on + strand, within Rv0134 at 162.212 kb on - strand, within Rv0134 at 162.212 kb on - strand, within Rv0134 at 162.212 kb on - strand, within Rv0134 at 162.212 kb on - strand, within Rv0134 at 162.280 kb on + strand, within Rv0134 at 162.280 kb on + strand, within Rv0134 at 162.356 kb on + strand, within Rv0134 at 162.356 kb on + strand, within Rv0134
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Delamanid 0.236 ug/mL remove 160,264 + Rv0132c 0.52 +2.2 160,264 + Rv0132c 0.52 -1.4 160,265 - Rv0132c 0.52 +0.5 160,265 - Rv0132c 0.52 +0.1 160,265 - Rv0132c 0.52 -0.2 160,302 - Rv0132c 0.56 -0.5 160,302 - Rv0132c 0.56 -0.6 160,427 + Rv0132c 0.67 +0.9 160,433 + Rv0132c 0.68 +0.5 160,433 + Rv0132c 0.68 -0.2 160,433 + Rv0132c 0.68 -1.8 160,434 - Rv0132c 0.68 -0.8 160,434 - Rv0132c 0.68 -0.1 160,434 - Rv0132c 0.68 +0.2 160,434 - Rv0132c 0.68 -0.1 160,436 - Rv0132c 0.68 -0.4 160,546 + Rv0132c 0.78 -1.4 160,546 + Rv0132c 0.78 -0.9 160,547 - Rv0132c 0.78 -0.8 160,547 - Rv0132c 0.78 -0.1 160,568 + Rv0132c 0.80 -0.3 160,569 - Rv0132c 0.80 -0.7 160,941 + Rv0133 0.12 -0.4 160,941 + Rv0133 0.12 -0.7 160,966 + Rv0133 0.16 +0.2 160,967 - Rv0133 0.16 -0.6 161,245 - Rv0133 0.62 -0.8 161,245 - Rv0133 0.62 -0.3 161,245 - Rv0133 0.62 -1.0 161,349 + Rv0133 0.79 -0.0 161,385 + Rv0133 0.85 -0.2 161,386 - Rv0133 0.85 -0.1 161,386 - Rv0133 0.85 -0.4 161,386 - Rv0133 0.85 -0.3 161,446 + +0.4 161,607 + -0.5 161,608 - +0.0 161,702 - -0.2 161,702 - -0.6 161,702 - -0.2 161,702 - -0.2 161,756 + -0.6 161,756 + +0.3 161,756 + -0.7 161,878 - Rv0134 0.12 -0.0 162,011 + Rv0134 0.27 -0.3 162,013 + Rv0134 0.27 -0.4 162,013 + Rv0134 0.27 +0.9 162,013 + Rv0134 0.27 -0.8 162,013 + Rv0134 0.27 -0.5 162,014 - Rv0134 0.27 +0.5 162,211 + Rv0134 0.49 -0.2 162,212 - Rv0134 0.49 -0.5 162,212 - Rv0134 0.49 -0.9 162,212 - Rv0134 0.49 -0.3 162,212 - Rv0134 0.49 +1.8 162,280 + Rv0134 0.56 -0.7 162,280 + Rv0134 0.56 +2.9 162,356 + Rv0134 0.65 +0.2 162,356 + Rv0134 0.65 -0.4
Or see this region's nucleotide sequence