Experiment: Doxycycline hyclate 0.0006 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt AO353_26600 and AO353_26605 overlap by 4 nucleotides AO353_26605 and AO353_26610 are separated by 83 nucleotides AO353_26610 and AO353_26615 are separated by 9 nucleotides
AO353_26600: AO353_26600 - disulfide bond formation protein DsbA, at 5,824,371 to 5,825,522
_26600
AO353_26605: AO353_26605 - MFS transporter, at 5,825,519 to 5,827,186
_26605
AO353_26610: AO353_26610 - hypothetical protein, at 5,827,270 to 5,828,070
_26610
AO353_26615: AO353_26615 - pyridine nucleotide-disulfide oxidoreductase, at 5,828,080 to 5,829,324
_26615
Position (kb) 5825
5826
5827
5828 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3
4
5 at 5824.574 kb on + strand, within AO353_26600 at 5824.574 kb on + strand, within AO353_26600 at 5824.574 kb on + strand, within AO353_26600 at 5824.574 kb on + strand, within AO353_26600 at 5824.574 kb on + strand, within AO353_26600 at 5824.575 kb on - strand, within AO353_26600 at 5824.575 kb on - strand, within AO353_26600 at 5824.575 kb on - strand, within AO353_26600 at 5824.575 kb on - strand, within AO353_26600 at 5824.575 kb on - strand, within AO353_26600 at 5824.628 kb on + strand, within AO353_26600 at 5824.629 kb on - strand, within AO353_26600 at 5824.735 kb on + strand, within AO353_26600 at 5824.736 kb on - strand, within AO353_26600 at 5825.016 kb on - strand, within AO353_26600 at 5825.182 kb on + strand, within AO353_26600 at 5825.182 kb on + strand, within AO353_26600 at 5825.182 kb on + strand, within AO353_26600 at 5825.182 kb on + strand, within AO353_26600 at 5825.183 kb on - strand, within AO353_26600 at 5825.183 kb on - strand, within AO353_26600 at 5825.260 kb on + strand, within AO353_26600 at 5825.289 kb on + strand, within AO353_26600 at 5825.290 kb on - strand, within AO353_26600 at 5825.359 kb on + strand, within AO353_26600 at 5825.359 kb on + strand, within AO353_26600 at 5825.359 kb on + strand, within AO353_26600 at 5825.359 kb on + strand, within AO353_26600 at 5825.359 kb on + strand, within AO353_26600 at 5825.359 kb on + strand, within AO353_26600 at 5825.359 kb on + strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.360 kb on - strand, within AO353_26600 at 5825.414 kb on + strand at 5825.414 kb on + strand at 5825.673 kb on + strand at 5825.674 kb on - strand at 5825.674 kb on - strand at 5825.762 kb on + strand, within AO353_26605 at 5825.762 kb on + strand, within AO353_26605 at 5825.762 kb on + strand, within AO353_26605 at 5825.763 kb on - strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.766 kb on + strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5825.767 kb on - strand, within AO353_26605 at 5826.023 kb on + strand, within AO353_26605 at 5826.023 kb on + strand, within AO353_26605 at 5826.023 kb on + strand, within AO353_26605 at 5826.024 kb on - strand, within AO353_26605 at 5826.039 kb on + strand, within AO353_26605 at 5826.039 kb on + strand at 5826.040 kb on - strand, within AO353_26605 at 5826.201 kb on + strand, within AO353_26605 at 5826.201 kb on + strand, within AO353_26605 at 5826.202 kb on - strand, within AO353_26605 at 5826.202 kb on - strand, within AO353_26605 at 5826.283 kb on + strand, within AO353_26605 at 5826.367 kb on + strand, within AO353_26605 at 5826.368 kb on - strand, within AO353_26605 at 5826.619 kb on - strand, within AO353_26605 at 5826.619 kb on - strand, within AO353_26605 at 5826.619 kb on - strand, within AO353_26605 at 5826.619 kb on - strand, within AO353_26605 at 5826.694 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.753 kb on + strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.754 kb on - strand, within AO353_26605 at 5826.756 kb on + strand, within AO353_26605 at 5826.756 kb on + strand, within AO353_26605 at 5826.756 kb on + strand, within AO353_26605 at 5826.756 kb on + strand, within AO353_26605 at 5826.756 kb on + strand, within AO353_26605 at 5826.757 kb on - strand, within AO353_26605 at 5826.757 kb on - strand, within AO353_26605 at 5826.757 kb on - strand, within AO353_26605 at 5826.790 kb on + strand, within AO353_26605 at 5826.791 kb on - strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand at 5826.864 kb on + strand, within AO353_26605 at 5826.864 kb on + strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.865 kb on - strand, within AO353_26605 at 5826.878 kb on + strand, within AO353_26605 at 5826.878 kb on + strand, within AO353_26605 at 5826.878 kb on + strand, within AO353_26605 at 5826.878 kb on + strand, within AO353_26605 at 5826.878 kb on + strand, within AO353_26605 at 5826.878 kb on + strand, within AO353_26605 at 5826.879 kb on - strand, within AO353_26605 at 5826.957 kb on + strand, within AO353_26605 at 5826.957 kb on + strand, within AO353_26605 at 5826.957 kb on + strand, within AO353_26605 at 5826.958 kb on - strand, within AO353_26605 at 5826.958 kb on - strand, within AO353_26605 at 5826.958 kb on - strand, within AO353_26605 at 5826.958 kb on - strand, within AO353_26605 at 5826.958 kb on - strand, within AO353_26605 at 5827.014 kb on + strand, within AO353_26605 at 5827.014 kb on + strand, within AO353_26605 at 5827.086 kb on + strand at 5827.087 kb on - strand at 5827.087 kb on - strand at 5827.112 kb on + strand at 5827.112 kb on + strand at 5827.113 kb on - strand at 5827.113 kb on - strand at 5827.218 kb on + strand at 5827.219 kb on - strand at 5827.289 kb on + strand at 5827.289 kb on + strand at 5827.289 kb on + strand at 5827.398 kb on + strand, within AO353_26610 at 5827.398 kb on + strand, within AO353_26610 at 5827.513 kb on + strand, within AO353_26610 at 5827.513 kb on + strand, within AO353_26610 at 5827.513 kb on + strand, within AO353_26610 at 5827.513 kb on + strand, within AO353_26610 at 5827.514 kb on - strand, within AO353_26610 at 5827.514 kb on - strand, within AO353_26610 at 5827.514 kb on - strand, within AO353_26610 at 5827.514 kb on - strand, within AO353_26610 at 5827.514 kb on - strand, within AO353_26610 at 5827.514 kb on - strand, within AO353_26610 at 5827.811 kb on + strand, within AO353_26610 at 5827.811 kb on + strand, within AO353_26610 at 5827.811 kb on + strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5827.812 kb on - strand, within AO353_26610 at 5828.071 kb on - strand at 5828.071 kb on - strand at 5828.071 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Doxycycline hyclate 0.0006 mg/ml remove 5,824,574 + AO353_26600 0.18 -1.4 5,824,574 + AO353_26600 0.18 +1.6 5,824,574 + AO353_26600 0.18 +0.4 5,824,574 + AO353_26600 0.18 +1.8 5,824,574 + AO353_26600 0.18 +1.4 5,824,575 - AO353_26600 0.18 -1.7 5,824,575 - AO353_26600 0.18 +2.0 5,824,575 - AO353_26600 0.18 -0.7 5,824,575 - AO353_26600 0.18 -1.7 5,824,575 - AO353_26600 0.18 -0.2 5,824,628 + AO353_26600 0.22 +2.2 5,824,629 - AO353_26600 0.22 +0.7 5,824,735 + AO353_26600 0.32 +0.4 5,824,736 - AO353_26600 0.32 +0.1 5,825,016 - AO353_26600 0.56 +1.4 5,825,182 + AO353_26600 0.70 -1.6 5,825,182 + AO353_26600 0.70 +2.3 5,825,182 + AO353_26600 0.70 -1.2 5,825,182 + AO353_26600 0.70 -1.6 5,825,183 - AO353_26600 0.70 -1.2 5,825,183 - AO353_26600 0.70 -1.2 5,825,260 + AO353_26600 0.77 -0.6 5,825,289 + AO353_26600 0.80 +1.4 5,825,290 - AO353_26600 0.80 -0.2 5,825,359 + AO353_26600 0.86 +1.6 5,825,359 + AO353_26600 0.86 -0.9 5,825,359 + AO353_26600 0.86 +0.4 5,825,359 + AO353_26600 0.86 +1.0 5,825,359 + AO353_26600 0.86 +0.0 5,825,359 + AO353_26600 0.86 +0.4 5,825,359 + AO353_26600 0.86 +2.6 5,825,360 - AO353_26600 0.86 +0.4 5,825,360 - AO353_26600 0.86 -0.9 5,825,360 - AO353_26600 0.86 -0.6 5,825,360 - AO353_26600 0.86 +0.1 5,825,360 - AO353_26600 0.86 -2.8 5,825,360 - AO353_26600 0.86 +1.9 5,825,360 - AO353_26600 0.86 +1.4 5,825,360 - AO353_26600 0.86 -2.3 5,825,360 - AO353_26600 0.86 -2.4 5,825,360 - AO353_26600 0.86 +2.2 5,825,414 + -1.6 5,825,414 + -1.2 5,825,673 + -2.7 5,825,674 - -2.4 5,825,674 - +1.4 5,825,762 + AO353_26605 0.15 -2.7 5,825,762 + AO353_26605 0.15 -2.0 5,825,762 + AO353_26605 0.15 -0.2 5,825,763 - AO353_26605 0.15 -1.4 5,825,766 + AO353_26605 0.15 +2.1 5,825,766 + AO353_26605 0.15 -0.2 5,825,766 + AO353_26605 0.15 +0.6 5,825,766 + AO353_26605 0.15 -1.2 5,825,766 + AO353_26605 0.15 +0.9 5,825,766 + AO353_26605 0.15 -1.6 5,825,766 + AO353_26605 0.15 +2.8 5,825,766 + AO353_26605 0.15 +1.4 5,825,766 + AO353_26605 0.15 -1.4 5,825,766 + AO353_26605 0.15 +1.4 5,825,766 + AO353_26605 0.15 -1.6 5,825,767 - AO353_26605 0.15 -0.6 5,825,767 - AO353_26605 0.15 +1.8 5,825,767 - AO353_26605 0.15 +1.4 5,825,767 - AO353_26605 0.15 -0.6 5,825,767 - AO353_26605 0.15 -0.6 5,825,767 - AO353_26605 0.15 +1.7 5,825,767 - AO353_26605 0.15 -1.4 5,825,767 - AO353_26605 0.15 -0.9 5,825,767 - AO353_26605 0.15 -1.3 5,825,767 - AO353_26605 0.15 -0.9 5,825,767 - AO353_26605 0.15 -2.3 5,825,767 - AO353_26605 0.15 -0.9 5,825,767 - AO353_26605 0.15 -0.2 5,826,023 + AO353_26605 0.30 -2.3 5,826,023 + AO353_26605 0.30 +0.6 5,826,023 + AO353_26605 0.30 -0.9 5,826,024 - AO353_26605 0.30 -0.2 5,826,039 + AO353_26605 0.31 -0.9 5,826,039 + -0.2 5,826,040 - AO353_26605 0.31 +2.4 5,826,201 + AO353_26605 0.41 -0.0 5,826,201 + AO353_26605 0.41 +0.1 5,826,202 - AO353_26605 0.41 -0.9 5,826,202 - AO353_26605 0.41 +1.8 5,826,283 + AO353_26605 0.46 -0.2 5,826,367 + AO353_26605 0.51 +2.7 5,826,368 - AO353_26605 0.51 +0.2 5,826,619 - AO353_26605 0.66 +0.8 5,826,619 - AO353_26605 0.66 -0.2 5,826,619 - AO353_26605 0.66 -0.9 5,826,619 - AO353_26605 0.66 -1.6 5,826,694 + AO353_26605 0.70 -1.9 5,826,753 + AO353_26605 0.74 -1.6 5,826,753 + AO353_26605 0.74 +2.0 5,826,753 + AO353_26605 0.74 +0.3 5,826,753 + AO353_26605 0.74 -1.6 5,826,753 + AO353_26605 0.74 -1.7 5,826,753 + AO353_26605 0.74 -0.6 5,826,753 + +0.4 5,826,753 + AO353_26605 0.74 +3.7 5,826,753 + AO353_26605 0.74 -1.9 5,826,753 + AO353_26605 0.74 +0.7 5,826,753 + AO353_26605 0.74 +2.2 5,826,753 + AO353_26605 0.74 +0.7 5,826,753 + AO353_26605 0.74 +0.6 5,826,753 + AO353_26605 0.74 -1.0 5,826,753 + AO353_26605 0.74 +0.4 5,826,753 + AO353_26605 0.74 +2.2 5,826,753 + AO353_26605 0.74 -0.2 5,826,753 + AO353_26605 0.74 -0.6 5,826,753 + AO353_26605 0.74 +1.9 5,826,753 + AO353_26605 0.74 -2.4 5,826,753 + AO353_26605 0.74 +0.4 5,826,753 + AO353_26605 0.74 -0.9 5,826,754 - AO353_26605 0.74 -1.7 5,826,754 - AO353_26605 0.74 -1.0 5,826,754 - AO353_26605 0.74 +1.1 5,826,754 - AO353_26605 0.74 -0.2 5,826,754 - AO353_26605 0.74 +0.2 5,826,754 - AO353_26605 0.74 -0.6 5,826,754 - AO353_26605 0.74 -0.9 5,826,754 - AO353_26605 0.74 +1.2 5,826,754 - AO353_26605 0.74 +1.4 5,826,754 - AO353_26605 0.74 -2.0 5,826,754 - AO353_26605 0.74 -1.7 5,826,754 - AO353_26605 0.74 +2.6 5,826,754 - AO353_26605 0.74 -2.0 5,826,754 - AO353_26605 0.74 -1.3 5,826,756 + AO353_26605 0.74 -0.9 5,826,756 + AO353_26605 0.74 -1.6 5,826,756 + AO353_26605 0.74 -0.6 5,826,756 + AO353_26605 0.74 -0.2 5,826,756 + AO353_26605 0.74 -1.6 5,826,757 - AO353_26605 0.74 -0.2 5,826,757 - AO353_26605 0.74 +0.4 5,826,757 - AO353_26605 0.74 +1.4 5,826,790 + AO353_26605 0.76 -1.7 5,826,791 - AO353_26605 0.76 -1.9 5,826,864 + AO353_26605 0.81 -1.4 5,826,864 + AO353_26605 0.81 -1.7 5,826,864 + AO353_26605 0.81 -0.6 5,826,864 + AO353_26605 0.81 -0.6 5,826,864 + AO353_26605 0.81 -2.4 5,826,864 + AO353_26605 0.81 +1.9 5,826,864 + AO353_26605 0.81 +0.1 5,826,864 + AO353_26605 0.81 +1.7 5,826,864 + AO353_26605 0.81 -2.0 5,826,864 + +0.4 5,826,864 + AO353_26605 0.81 +1.6 5,826,864 + AO353_26605 0.81 +2.4 5,826,865 - AO353_26605 0.81 -0.9 5,826,865 - AO353_26605 0.81 -1.9 5,826,865 - AO353_26605 0.81 +4.9 5,826,865 - AO353_26605 0.81 +1.7 5,826,865 - AO353_26605 0.81 +2.2 5,826,865 - AO353_26605 0.81 -2.5 5,826,865 - AO353_26605 0.81 -1.4 5,826,865 - AO353_26605 0.81 -0.2 5,826,865 - AO353_26605 0.81 +1.2 5,826,865 - AO353_26605 0.81 -0.0 5,826,878 + AO353_26605 0.81 -1.4 5,826,878 + AO353_26605 0.81 +2.4 5,826,878 + AO353_26605 0.81 -0.8 5,826,878 + AO353_26605 0.81 -1.7 5,826,878 + AO353_26605 0.81 -1.2 5,826,878 + AO353_26605 0.81 -0.9 5,826,879 - AO353_26605 0.82 +0.8 5,826,957 + AO353_26605 0.86 +2.9 5,826,957 + AO353_26605 0.86 +3.0 5,826,957 + AO353_26605 0.86 -0.9 5,826,958 - AO353_26605 0.86 -1.2 5,826,958 - AO353_26605 0.86 -2.3 5,826,958 - AO353_26605 0.86 -1.0 5,826,958 - AO353_26605 0.86 -3.0 5,826,958 - AO353_26605 0.86 +1.4 5,827,014 + AO353_26605 0.90 -0.2 5,827,014 + AO353_26605 0.90 -2.6 5,827,086 + +0.4 5,827,087 - +2.4 5,827,087 - -0.6 5,827,112 + +1.4 5,827,112 + +0.4 5,827,113 - -1.4 5,827,113 - +1.4 5,827,218 + -2.0 5,827,219 - -0.2 5,827,289 + -0.7 5,827,289 + +0.6 5,827,289 + +0.8 5,827,398 + AO353_26610 0.16 +0.4 5,827,398 + AO353_26610 0.16 +1.4 5,827,513 + AO353_26610 0.30 -0.6 5,827,513 + AO353_26610 0.30 -0.8 5,827,513 + AO353_26610 0.30 -1.6 5,827,513 + AO353_26610 0.30 -0.9 5,827,514 - AO353_26610 0.30 -1.9 5,827,514 - AO353_26610 0.30 +2.7 5,827,514 - AO353_26610 0.30 -0.2 5,827,514 - AO353_26610 0.30 -0.2 5,827,514 - AO353_26610 0.30 +2.1 5,827,514 - AO353_26610 0.30 -1.5 5,827,811 + AO353_26610 0.68 +2.3 5,827,811 + AO353_26610 0.68 -0.9 5,827,811 + AO353_26610 0.68 -2.5 5,827,812 - AO353_26610 0.68 -0.2 5,827,812 - AO353_26610 0.68 -0.7 5,827,812 - AO353_26610 0.68 -1.4 5,827,812 - AO353_26610 0.68 -0.6 5,827,812 - AO353_26610 0.68 +0.3 5,827,812 - AO353_26610 0.68 -0.4 5,827,812 - AO353_26610 0.68 +1.1 5,827,812 - AO353_26610 0.68 -1.6 5,827,812 - AO353_26610 0.68 -1.4 5,828,071 - +0.9 5,828,071 - -0.7 5,828,071 - -1.4
Or see this region's nucleotide sequence