Experiment: Doxycycline hyclate 0.00078125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt ligA and hoxE are separated by 124 nucleotides hoxE and hoxF overlap by 1 nucleotides hoxF and cinA are separated by 9 nucleotides
Synpcc7942_0277: ligA - NAD-dependent DNA ligase LigA, at 271,493 to 273,532
ligA
Synpcc7942_0278: hoxE - bidirectional hydrogenase complex protein HoxE, at 273,657 to 274,154
hoxE
Synpcc7942_0279: hoxF - NADH dehydrogenase (quinone), at 274,154 to 275,758
hoxF
Synpcc7942_0280: cinA - competence damage-inducible protein A, at 275,768 to 277,033
cinA
Position (kb) 274
275
276 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3 at 273.533 kb on + strand at 273.536 kb on - strand at 273.557 kb on - strand at 273.622 kb on + strand at 273.622 kb on + strand at 273.623 kb on - strand at 273.628 kb on - strand at 273.641 kb on - strand at 273.644 kb on - strand at 273.648 kb on + strand at 273.656 kb on - strand at 273.656 kb on - strand at 273.656 kb on - strand at 273.677 kb on + strand at 273.682 kb on + strand at 273.725 kb on - strand, within hoxE at 273.747 kb on - strand, within hoxE at 273.776 kb on + strand, within hoxE at 273.777 kb on + strand, within hoxE at 273.777 kb on + strand, within hoxE at 273.784 kb on - strand, within hoxE at 273.784 kb on - strand, within hoxE at 273.790 kb on - strand, within hoxE at 273.811 kb on + strand, within hoxE at 273.828 kb on + strand, within hoxE at 273.853 kb on - strand, within hoxE at 273.853 kb on - strand, within hoxE at 273.862 kb on + strand, within hoxE at 273.865 kb on + strand, within hoxE at 273.873 kb on - strand, within hoxE at 273.875 kb on + strand, within hoxE at 273.883 kb on - strand, within hoxE at 273.964 kb on + strand, within hoxE at 273.972 kb on - strand, within hoxE at 273.975 kb on + strand, within hoxE at 273.993 kb on + strand, within hoxE at 274.001 kb on - strand, within hoxE at 274.002 kb on + strand, within hoxE at 274.010 kb on - strand, within hoxE at 274.022 kb on + strand, within hoxE at 274.022 kb on + strand, within hoxE at 274.029 kb on + strand, within hoxE at 274.035 kb on - strand, within hoxE at 274.037 kb on + strand, within hoxE at 274.037 kb on - strand, within hoxE at 274.039 kb on + strand at 274.039 kb on + strand, within hoxE at 274.039 kb on + strand, within hoxE at 274.039 kb on + strand, within hoxE at 274.039 kb on + strand, within hoxE at 274.039 kb on + strand, within hoxE at 274.039 kb on + strand, within hoxE at 274.041 kb on + strand, within hoxE at 274.045 kb on - strand, within hoxE at 274.047 kb on - strand, within hoxE at 274.047 kb on - strand, within hoxE at 274.047 kb on - strand, within hoxE at 274.081 kb on - strand, within hoxE at 274.083 kb on - strand, within hoxE at 274.086 kb on + strand, within hoxE at 274.094 kb on - strand, within hoxE at 274.125 kb on - strand at 274.133 kb on - strand at 274.139 kb on + strand at 274.147 kb on - strand at 274.151 kb on + strand at 274.156 kb on + strand at 274.166 kb on + strand at 274.174 kb on - strand at 274.175 kb on + strand at 274.208 kb on - strand at 274.231 kb on + strand at 274.238 kb on + strand at 274.239 kb on - strand at 274.285 kb on - strand at 274.285 kb on - strand at 274.285 kb on - strand at 274.315 kb on + strand, within hoxF at 274.338 kb on + strand, within hoxF at 274.343 kb on + strand at 274.353 kb on - strand, within hoxF at 274.353 kb on - strand, within hoxF at 274.356 kb on - strand, within hoxF at 274.362 kb on + strand, within hoxF at 274.364 kb on + strand, within hoxF at 274.376 kb on + strand, within hoxF at 274.388 kb on + strand, within hoxF at 274.388 kb on + strand, within hoxF at 274.397 kb on + strand, within hoxF at 274.398 kb on - strand, within hoxF at 274.398 kb on - strand, within hoxF at 274.402 kb on + strand, within hoxF at 274.402 kb on + strand, within hoxF at 274.410 kb on - strand, within hoxF at 274.415 kb on - strand, within hoxF at 274.446 kb on - strand, within hoxF at 274.447 kb on - strand, within hoxF at 274.459 kb on - strand, within hoxF at 274.485 kb on - strand, within hoxF at 274.488 kb on + strand, within hoxF at 274.509 kb on - strand, within hoxF at 274.534 kb on - strand, within hoxF at 274.544 kb on - strand, within hoxF at 274.554 kb on - strand, within hoxF at 274.595 kb on + strand, within hoxF at 274.603 kb on - strand, within hoxF at 274.646 kb on - strand, within hoxF at 274.689 kb on - strand, within hoxF at 274.761 kb on + strand, within hoxF at 274.769 kb on - strand, within hoxF at 274.769 kb on - strand, within hoxF at 274.778 kb on + strand, within hoxF at 274.778 kb on + strand, within hoxF at 274.778 kb on + strand, within hoxF at 274.778 kb on + strand, within hoxF at 274.778 kb on + strand, within hoxF at 274.786 kb on - strand, within hoxF at 274.786 kb on - strand, within hoxF at 274.786 kb on - strand, within hoxF at 274.786 kb on - strand, within hoxF at 274.791 kb on + strand, within hoxF at 274.794 kb on + strand, within hoxF at 274.799 kb on - strand, within hoxF at 274.802 kb on + strand, within hoxF at 274.839 kb on + strand, within hoxF at 274.898 kb on + strand, within hoxF at 274.946 kb on + strand, within hoxF at 274.946 kb on + strand, within hoxF at 274.946 kb on + strand, within hoxF at 274.946 kb on + strand, within hoxF at 274.954 kb on - strand, within hoxF at 274.987 kb on - strand, within hoxF at 275.065 kb on - strand, within hoxF at 275.065 kb on - strand, within hoxF at 275.078 kb on - strand, within hoxF at 275.103 kb on + strand, within hoxF at 275.103 kb on + strand, within hoxF at 275.103 kb on + strand, within hoxF at 275.111 kb on - strand, within hoxF at 275.111 kb on - strand, within hoxF at 275.111 kb on - strand, within hoxF at 275.113 kb on + strand, within hoxF at 275.139 kb on + strand, within hoxF at 275.150 kb on + strand, within hoxF at 275.226 kb on + strand, within hoxF at 275.314 kb on - strand, within hoxF at 275.350 kb on - strand, within hoxF at 275.356 kb on + strand, within hoxF at 275.381 kb on - strand, within hoxF at 275.382 kb on - strand, within hoxF at 275.405 kb on - strand, within hoxF at 275.407 kb on + strand, within hoxF at 275.441 kb on - strand, within hoxF at 275.455 kb on - strand, within hoxF at 275.457 kb on + strand, within hoxF at 275.457 kb on + strand, within hoxF at 275.501 kb on + strand, within hoxF at 275.543 kb on + strand, within hoxF at 275.550 kb on + strand, within hoxF at 275.551 kb on - strand, within hoxF at 275.569 kb on + strand, within hoxF at 275.569 kb on - strand, within hoxF at 275.579 kb on + strand, within hoxF at 275.579 kb on + strand, within hoxF at 275.587 kb on - strand, within hoxF at 275.598 kb on + strand at 275.598 kb on + strand at 275.606 kb on - strand at 275.606 kb on - strand at 275.609 kb on + strand at 275.616 kb on - strand at 275.660 kb on - strand at 275.661 kb on + strand at 275.680 kb on + strand at 275.682 kb on + strand at 275.692 kb on + strand at 275.710 kb on - strand at 275.715 kb on + strand at 275.735 kb on - strand at 275.751 kb on + strand at 275.759 kb on - strand at 275.789 kb on + strand at 275.856 kb on + strand at 275.864 kb on - strand at 275.864 kb on - strand at 275.864 kb on - strand at 275.866 kb on + strand at 275.871 kb on + strand at 275.893 kb on - strand at 275.912 kb on - strand, within cinA at 275.912 kb on - strand, within cinA at 275.973 kb on + strand, within cinA at 275.993 kb on + strand, within cinA at 276.003 kb on - strand, within cinA at 276.016 kb on + strand, within cinA at 276.016 kb on + strand, within cinA at 276.020 kb on + strand, within cinA at 276.024 kb on - strand, within cinA at 276.025 kb on + strand, within cinA at 276.069 kb on + strand, within cinA at 276.095 kb on + strand, within cinA at 276.103 kb on - strand, within cinA at 276.116 kb on + strand, within cinA at 276.145 kb on - strand, within cinA at 276.182 kb on + strand, within cinA at 276.220 kb on + strand, within cinA at 276.228 kb on - strand, within cinA at 276.251 kb on + strand, within cinA at 276.271 kb on - strand, within cinA at 276.292 kb on + strand, within cinA at 276.292 kb on + strand, within cinA at 276.300 kb on - strand, within cinA at 276.300 kb on - strand, within cinA at 276.316 kb on + strand, within cinA at 276.319 kb on - strand, within cinA at 276.338 kb on - strand, within cinA at 276.348 kb on + strand, within cinA at 276.376 kb on + strand, within cinA at 276.386 kb on + strand, within cinA at 276.409 kb on + strand, within cinA at 276.417 kb on - strand, within cinA at 276.514 kb on + strand, within cinA at 276.521 kb on - strand, within cinA at 276.521 kb on - strand, within cinA at 276.531 kb on - strand, within cinA at 276.572 kb on + strand, within cinA at 276.589 kb on - strand, within cinA at 276.638 kb on - strand, within cinA at 276.695 kb on - strand, within cinA at 276.695 kb on - strand, within cinA at 276.750 kb on + strand, within cinA at 276.751 kb on - strand, within cinA
Per-strain Table
Position Strand Gene LocusTag Fraction Doxycycline hyclate 0.00078125 mg/ml remove 273,533 + -0.4 273,536 - +1.5 273,557 - +0.2 273,622 + +0.9 273,622 + +0.3 273,623 - -0.1 273,628 - +0.6 273,641 - +0.9 273,644 - -2.3 273,648 + -0.1 273,656 - -2.1 273,656 - -0.1 273,656 - +0.8 273,677 + -1.1 273,682 + +0.5 273,725 - hoxE Synpcc7942_0278 0.14 -0.7 273,747 - hoxE Synpcc7942_0278 0.18 -1.7 273,776 + hoxE Synpcc7942_0278 0.24 +0.7 273,777 + hoxE Synpcc7942_0278 0.24 +0.7 273,777 + hoxE Synpcc7942_0278 0.24 +0.3 273,784 - hoxE Synpcc7942_0278 0.26 +0.8 273,784 - hoxE Synpcc7942_0278 0.26 +1.0 273,790 - hoxE Synpcc7942_0278 0.27 +0.1 273,811 + hoxE Synpcc7942_0278 0.31 -0.1 273,828 + hoxE Synpcc7942_0278 0.34 -0.3 273,853 - hoxE Synpcc7942_0278 0.39 +0.5 273,853 - hoxE Synpcc7942_0278 0.39 +1.6 273,862 + hoxE Synpcc7942_0278 0.41 +0.2 273,865 + hoxE Synpcc7942_0278 0.42 +0.8 273,873 - hoxE Synpcc7942_0278 0.43 +1.1 273,875 + hoxE Synpcc7942_0278 0.44 +0.1 273,883 - hoxE Synpcc7942_0278 0.45 +0.1 273,964 + hoxE Synpcc7942_0278 0.62 +1.3 273,972 - hoxE Synpcc7942_0278 0.63 -0.5 273,975 + hoxE Synpcc7942_0278 0.64 -1.7 273,993 + hoxE Synpcc7942_0278 0.67 -0.7 274,001 - hoxE Synpcc7942_0278 0.69 +0.6 274,002 + hoxE Synpcc7942_0278 0.69 -0.6 274,010 - hoxE Synpcc7942_0278 0.71 +0.3 274,022 + hoxE Synpcc7942_0278 0.73 -0.1 274,022 + hoxE Synpcc7942_0278 0.73 +0.1 274,029 + hoxE Synpcc7942_0278 0.75 +0.1 274,035 - hoxE Synpcc7942_0278 0.76 +1.2 274,037 + hoxE Synpcc7942_0278 0.76 -0.6 274,037 - hoxE Synpcc7942_0278 0.76 +0.8 274,039 + +1.5 274,039 + hoxE Synpcc7942_0278 0.77 +1.9 274,039 + hoxE Synpcc7942_0278 0.77 +0.1 274,039 + hoxE Synpcc7942_0278 0.77 -1.7 274,039 + hoxE Synpcc7942_0278 0.77 -0.1 274,039 + hoxE Synpcc7942_0278 0.77 -0.5 274,039 + hoxE Synpcc7942_0278 0.77 -0.5 274,041 + hoxE Synpcc7942_0278 0.77 +0.6 274,045 - hoxE Synpcc7942_0278 0.78 +1.2 274,047 - hoxE Synpcc7942_0278 0.78 +0.9 274,047 - hoxE Synpcc7942_0278 0.78 +0.5 274,047 - hoxE Synpcc7942_0278 0.78 +1.1 274,081 - hoxE Synpcc7942_0278 0.85 +0.3 274,083 - hoxE Synpcc7942_0278 0.86 +2.3 274,086 + hoxE Synpcc7942_0278 0.86 +0.5 274,094 - hoxE Synpcc7942_0278 0.88 -0.9 274,125 - +1.9 274,133 - -0.4 274,139 + +0.4 274,147 - -0.1 274,151 + -2.4 274,156 + -0.1 274,166 + +1.1 274,174 - -0.3 274,175 + +1.5 274,208 - +1.1 274,231 + +1.1 274,238 + +0.9 274,239 - -0.3 274,285 - +0.3 274,285 - +0.2 274,285 - -0.8 274,315 + hoxF Synpcc7942_0279 0.10 -0.1 274,338 + hoxF Synpcc7942_0279 0.11 +1.2 274,343 + +0.9 274,353 - hoxF Synpcc7942_0279 0.12 -0.3 274,353 - hoxF Synpcc7942_0279 0.12 +0.8 274,356 - hoxF Synpcc7942_0279 0.13 +1.5 274,362 + hoxF Synpcc7942_0279 0.13 +1.7 274,364 + hoxF Synpcc7942_0279 0.13 -2.1 274,376 + hoxF Synpcc7942_0279 0.14 +0.5 274,388 + hoxF Synpcc7942_0279 0.15 -0.8 274,388 + hoxF Synpcc7942_0279 0.15 -0.1 274,397 + hoxF Synpcc7942_0279 0.15 -1.1 274,398 - hoxF Synpcc7942_0279 0.15 +0.9 274,398 - hoxF Synpcc7942_0279 0.15 +0.1 274,402 + hoxF Synpcc7942_0279 0.15 -0.2 274,402 + hoxF Synpcc7942_0279 0.15 +1.3 274,410 - hoxF Synpcc7942_0279 0.16 +1.2 274,415 - hoxF Synpcc7942_0279 0.16 +1.6 274,446 - hoxF Synpcc7942_0279 0.18 +0.4 274,447 - hoxF Synpcc7942_0279 0.18 -2.1 274,459 - hoxF Synpcc7942_0279 0.19 +1.1 274,485 - hoxF Synpcc7942_0279 0.21 +0.5 274,488 + hoxF Synpcc7942_0279 0.21 -0.9 274,509 - hoxF Synpcc7942_0279 0.22 +0.8 274,534 - hoxF Synpcc7942_0279 0.24 +1.4 274,544 - hoxF Synpcc7942_0279 0.24 +0.1 274,554 - hoxF Synpcc7942_0279 0.25 +1.5 274,595 + hoxF Synpcc7942_0279 0.27 -2.4 274,603 - hoxF Synpcc7942_0279 0.28 -0.8 274,646 - hoxF Synpcc7942_0279 0.31 +0.6 274,689 - hoxF Synpcc7942_0279 0.33 -0.4 274,761 + hoxF Synpcc7942_0279 0.38 -1.0 274,769 - hoxF Synpcc7942_0279 0.38 +1.3 274,769 - hoxF Synpcc7942_0279 0.38 +1.5 274,778 + hoxF Synpcc7942_0279 0.39 -1.4 274,778 + hoxF Synpcc7942_0279 0.39 -0.8 274,778 + hoxF Synpcc7942_0279 0.39 -1.2 274,778 + hoxF Synpcc7942_0279 0.39 +0.2 274,778 + hoxF Synpcc7942_0279 0.39 +1.1 274,786 - hoxF Synpcc7942_0279 0.39 -2.3 274,786 - hoxF Synpcc7942_0279 0.39 +1.7 274,786 - hoxF Synpcc7942_0279 0.39 -1.0 274,786 - hoxF Synpcc7942_0279 0.39 -0.1 274,791 + hoxF Synpcc7942_0279 0.40 +0.2 274,794 + hoxF Synpcc7942_0279 0.40 +1.7 274,799 - hoxF Synpcc7942_0279 0.40 +0.5 274,802 + hoxF Synpcc7942_0279 0.40 +0.5 274,839 + hoxF Synpcc7942_0279 0.43 -0.6 274,898 + hoxF Synpcc7942_0279 0.46 -0.4 274,946 + hoxF Synpcc7942_0279 0.49 -0.5 274,946 + hoxF Synpcc7942_0279 0.49 -1.1 274,946 + hoxF Synpcc7942_0279 0.49 +0.9 274,946 + hoxF Synpcc7942_0279 0.49 -0.2 274,954 - hoxF Synpcc7942_0279 0.50 -0.1 274,987 - hoxF Synpcc7942_0279 0.52 +0.4 275,065 - hoxF Synpcc7942_0279 0.57 +1.3 275,065 - hoxF Synpcc7942_0279 0.57 -3.7 275,078 - hoxF Synpcc7942_0279 0.58 +2.9 275,103 + hoxF Synpcc7942_0279 0.59 +0.9 275,103 + hoxF Synpcc7942_0279 0.59 -0.1 275,103 + hoxF Synpcc7942_0279 0.59 +1.4 275,111 - hoxF Synpcc7942_0279 0.60 +0.4 275,111 - hoxF Synpcc7942_0279 0.60 +0.9 275,111 - hoxF Synpcc7942_0279 0.60 +1.0 275,113 + hoxF Synpcc7942_0279 0.60 +1.0 275,139 + hoxF Synpcc7942_0279 0.61 +0.3 275,150 + hoxF Synpcc7942_0279 0.62 -0.1 275,226 + hoxF Synpcc7942_0279 0.67 +0.8 275,314 - hoxF Synpcc7942_0279 0.72 +1.5 275,350 - hoxF Synpcc7942_0279 0.75 -0.1 275,356 + hoxF Synpcc7942_0279 0.75 +0.2 275,381 - hoxF Synpcc7942_0279 0.76 +0.5 275,382 - hoxF Synpcc7942_0279 0.77 +0.6 275,405 - hoxF Synpcc7942_0279 0.78 -0.1 275,407 + hoxF Synpcc7942_0279 0.78 +0.8 275,441 - hoxF Synpcc7942_0279 0.80 -0.4 275,455 - hoxF Synpcc7942_0279 0.81 +1.4 275,457 + hoxF Synpcc7942_0279 0.81 +0.9 275,457 + hoxF Synpcc7942_0279 0.81 +0.6 275,501 + hoxF Synpcc7942_0279 0.84 -0.8 275,543 + hoxF Synpcc7942_0279 0.87 +0.1 275,550 + hoxF Synpcc7942_0279 0.87 +1.0 275,551 - hoxF Synpcc7942_0279 0.87 +0.6 275,569 + hoxF Synpcc7942_0279 0.88 -2.0 275,569 - hoxF Synpcc7942_0279 0.88 +1.3 275,579 + hoxF Synpcc7942_0279 0.89 -0.3 275,579 + hoxF Synpcc7942_0279 0.89 -0.3 275,587 - hoxF Synpcc7942_0279 0.89 +2.1 275,598 + +1.6 275,598 + -0.5 275,606 - +0.9 275,606 - -1.7 275,609 + -1.7 275,616 - -0.8 275,660 - +0.5 275,661 + +1.7 275,680 + +0.5 275,682 + +0.1 275,692 + +0.6 275,710 - +1.0 275,715 + +1.1 275,735 - +1.1 275,751 + +0.7 275,759 - -0.1 275,789 + +1.9 275,856 + -0.1 275,864 - -0.4 275,864 - -0.4 275,864 - -0.2 275,866 + +0.5 275,871 + -0.5 275,893 - +2.5 275,912 - cinA Synpcc7942_0280 0.11 -0.2 275,912 - cinA Synpcc7942_0280 0.11 +0.6 275,973 + cinA Synpcc7942_0280 0.16 -0.7 275,993 + cinA Synpcc7942_0280 0.18 +1.5 276,003 - cinA Synpcc7942_0280 0.19 -0.7 276,016 + cinA Synpcc7942_0280 0.20 +0.6 276,016 + cinA Synpcc7942_0280 0.20 +0.9 276,020 + cinA Synpcc7942_0280 0.20 +1.4 276,024 - cinA Synpcc7942_0280 0.20 +3.2 276,025 + cinA Synpcc7942_0280 0.20 +0.3 276,069 + cinA Synpcc7942_0280 0.24 -0.1 276,095 + cinA Synpcc7942_0280 0.26 +0.9 276,103 - cinA Synpcc7942_0280 0.26 +0.3 276,116 + cinA Synpcc7942_0280 0.27 -0.1 276,145 - cinA Synpcc7942_0280 0.30 +0.4 276,182 + cinA Synpcc7942_0280 0.33 -0.6 276,220 + cinA Synpcc7942_0280 0.36 +0.5 276,228 - cinA Synpcc7942_0280 0.36 +1.5 276,251 + cinA Synpcc7942_0280 0.38 -1.0 276,271 - cinA Synpcc7942_0280 0.40 -0.5 276,292 + cinA Synpcc7942_0280 0.41 +0.1 276,292 + cinA Synpcc7942_0280 0.41 +1.0 276,300 - cinA Synpcc7942_0280 0.42 -0.3 276,300 - cinA Synpcc7942_0280 0.42 +0.8 276,316 + cinA Synpcc7942_0280 0.43 -1.1 276,319 - cinA Synpcc7942_0280 0.44 +0.3 276,338 - cinA Synpcc7942_0280 0.45 -0.1 276,348 + cinA Synpcc7942_0280 0.46 -0.1 276,376 + cinA Synpcc7942_0280 0.48 -2.4 276,386 + cinA Synpcc7942_0280 0.49 +0.4 276,409 + cinA Synpcc7942_0280 0.51 +0.4 276,417 - cinA Synpcc7942_0280 0.51 +0.6 276,514 + cinA Synpcc7942_0280 0.59 +0.1 276,521 - cinA Synpcc7942_0280 0.59 +1.2 276,521 - cinA Synpcc7942_0280 0.59 +0.9 276,531 - cinA Synpcc7942_0280 0.60 +0.7 276,572 + cinA Synpcc7942_0280 0.64 +0.6 276,589 - cinA Synpcc7942_0280 0.65 +0.4 276,638 - cinA Synpcc7942_0280 0.69 +0.1 276,695 - cinA Synpcc7942_0280 0.73 -0.4 276,695 - cinA Synpcc7942_0280 0.73 +0.6 276,750 + cinA Synpcc7942_0280 0.78 +2.2 276,751 - cinA Synpcc7942_0280 0.78 -1.1
Or see this region's nucleotide sequence