Experiment: L-Isoleucine (C)
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Pf1N1B4_651 and Pf1N1B4_652 are separated by 45 nucleotides Pf1N1B4_652 and Pf1N1B4_653 are separated by 2 nucleotides Pf1N1B4_653 and Pf1N1B4_654 are separated by 134 nucleotides
Pf1N1B4_651 - 2-dehydropantoate 2-reductase (EC 1.1.1.169), at 744,679 to 745,596
_651
Pf1N1B4_652 - Sensory box histidine kinase, at 745,642 to 747,678
_652
Pf1N1B4_653 - ATP:Cob(I)alamin adenosyltransferase (EC 2.5.1.17), at 747,681 to 748,262
_653
Pf1N1B4_654 - Mutator mutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) (EC 3.6.1.-) / Thiamin-phosphate pyrophosphorylase-like protein, at 748,397 to 749,341
_654
Position (kb)
745
746
747
748 Strain fitness (log2 ratio)
-4
-3
-2
-1
0
1
2
3 at 744.696 kb on + strand at 744.696 kb on + strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.697 kb on - strand at 744.791 kb on + strand, within Pf1N1B4_651 at 744.792 kb on - strand, within Pf1N1B4_651 at 744.792 kb on - strand, within Pf1N1B4_651 at 744.792 kb on - strand at 744.850 kb on + strand, within Pf1N1B4_651 at 744.850 kb on + strand, within Pf1N1B4_651 at 744.903 kb on - strand, within Pf1N1B4_651 at 744.903 kb on - strand, within Pf1N1B4_651 at 744.919 kb on + strand, within Pf1N1B4_651 at 744.919 kb on + strand, within Pf1N1B4_651 at 745.114 kb on + strand, within Pf1N1B4_651 at 745.115 kb on - strand, within Pf1N1B4_651 at 745.182 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.438 kb on + strand, within Pf1N1B4_651 at 745.439 kb on - strand, within Pf1N1B4_651 at 745.439 kb on - strand, within Pf1N1B4_651 at 745.477 kb on + strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.478 kb on - strand, within Pf1N1B4_651 at 745.490 kb on - strand, within Pf1N1B4_651 at 745.629 kb on - strand at 745.747 kb on - strand at 745.759 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.762 kb on + strand at 745.763 kb on - strand at 745.763 kb on - strand at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.894 kb on + strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.895 kb on - strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand at 745.896 kb on + strand, within Pf1N1B4_652 at 745.896 kb on + strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.897 kb on - strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.921 kb on + strand, within Pf1N1B4_652 at 745.922 kb on - strand at 745.922 kb on - strand, within Pf1N1B4_652 at 745.922 kb on - strand, within Pf1N1B4_652 at 745.976 kb on + strand, within Pf1N1B4_652 at 746.113 kb on + strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.114 kb on - strand, within Pf1N1B4_652 at 746.166 kb on - strand, within Pf1N1B4_652 at 746.260 kb on + strand, within Pf1N1B4_652 at 746.260 kb on + strand, within Pf1N1B4_652 at 746.261 kb on - strand, within Pf1N1B4_652 at 746.261 kb on - strand, within Pf1N1B4_652 at 746.261 kb on - strand, within Pf1N1B4_652 at 746.504 kb on - strand, within Pf1N1B4_652 at 746.504 kb on - strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.563 kb on + strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.564 kb on - strand, within Pf1N1B4_652 at 746.567 kb on + strand, within Pf1N1B4_652 at 746.756 kb on - strand, within Pf1N1B4_652 at 746.916 kb on + strand, within Pf1N1B4_652 at 746.916 kb on + strand, within Pf1N1B4_652 at 746.916 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.945 kb on + strand, within Pf1N1B4_652 at 746.946 kb on - strand, within Pf1N1B4_652 at 747.037 kb on + strand at 747.038 kb on - strand, within Pf1N1B4_652 at 747.361 kb on - strand, within Pf1N1B4_652 at 747.396 kb on + strand, within Pf1N1B4_652 at 747.396 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.474 kb on + strand, within Pf1N1B4_652 at 747.475 kb on - strand at 747.475 kb on - strand at 747.541 kb on + strand at 747.541 kb on + strand at 747.676 kb on + strand at 747.705 kb on + strand at 747.706 kb on - strand at 747.706 kb on - strand at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.854 kb on + strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.855 kb on - strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.858 kb on + strand, within Pf1N1B4_653 at 747.945 kb on + strand, within Pf1N1B4_653 at 747.946 kb on - strand, within Pf1N1B4_653 at 747.946 kb on - strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.072 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.155 kb on + strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.156 kb on - strand, within Pf1N1B4_653 at 748.157 kb on + strand, within Pf1N1B4_653 at 748.157 kb on + strand, within Pf1N1B4_653 at 748.157 kb on + strand, within Pf1N1B4_653 at 748.158 kb on - strand, within Pf1N1B4_653 at 748.158 kb on - strand, within Pf1N1B4_653 at 748.260 kb on + strand at 748.320 kb on + strand at 748.508 kb on - strand, within Pf1N1B4_654 at 748.525 kb on + strand, within Pf1N1B4_654 at 748.525 kb on + strand, within Pf1N1B4_654 at 748.525 kb on + strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654 at 748.526 kb on - strand, within Pf1N1B4_654
Per-strain Table
Position Strand Gene LocusTag Fraction L-Isoleucine (C) remove 744,696 + -0.3 744,696 + -1.2 744,697 - -0.8 744,697 - -0.0 744,697 - -1.2 744,697 - -1.6 744,697 - -1.0 744,697 - -2.0 744,697 - +0.6 744,791 + Pf1N1B4_651 0.12 -0.8 744,792 - Pf1N1B4_651 0.12 +0.3 744,792 - Pf1N1B4_651 0.12 -1.0 744,792 - +0.6 744,850 + Pf1N1B4_651 0.19 -0.0 744,850 + Pf1N1B4_651 0.19 +2.0 744,903 - Pf1N1B4_651 0.24 +2.0 744,903 - Pf1N1B4_651 0.24 -2.3 744,919 + Pf1N1B4_651 0.26 -0.0 744,919 + Pf1N1B4_651 0.26 -1.8 745,114 + Pf1N1B4_651 0.47 -0.9 745,115 - Pf1N1B4_651 0.47 -0.8 745,182 + Pf1N1B4_651 0.55 -1.0 745,438 + Pf1N1B4_651 0.83 -1.0 745,438 + Pf1N1B4_651 0.83 -0.3 745,438 + Pf1N1B4_651 0.83 +1.5 745,438 + Pf1N1B4_651 0.83 -1.4 745,439 - Pf1N1B4_651 0.83 -0.8 745,439 - Pf1N1B4_651 0.83 -0.4 745,477 + Pf1N1B4_651 0.87 -0.0 745,478 - Pf1N1B4_651 0.87 -0.0 745,478 - Pf1N1B4_651 0.87 +1.0 745,478 - Pf1N1B4_651 0.87 -0.4 745,478 - Pf1N1B4_651 0.87 -0.4 745,490 - Pf1N1B4_651 0.88 -0.5 745,629 - -2.0 745,747 - -2.0 745,759 + -2.8 745,762 + -1.6 745,762 + -1.0 745,762 + -2.3 745,762 + -1.0 745,762 + +0.4 745,762 + -2.3 745,762 + -2.3 745,763 - -1.6 745,763 - -1.0 745,894 + Pf1N1B4_652 0.12 -2.0 745,894 + -2.0 745,894 + Pf1N1B4_652 0.12 -2.8 745,894 + Pf1N1B4_652 0.12 -2.0 745,894 + Pf1N1B4_652 0.12 -3.0 745,894 + Pf1N1B4_652 0.12 -0.0 745,894 + Pf1N1B4_652 0.12 -0.0 745,895 - Pf1N1B4_652 0.12 -2.0 745,895 - Pf1N1B4_652 0.12 -2.0 745,895 - Pf1N1B4_652 0.12 -2.3 745,895 - Pf1N1B4_652 0.12 -1.0 745,895 - Pf1N1B4_652 0.12 +1.6 745,895 - Pf1N1B4_652 0.12 -1.6 745,896 + Pf1N1B4_652 0.12 -1.0 745,896 + Pf1N1B4_652 0.12 -2.0 745,896 + Pf1N1B4_652 0.12 -2.6 745,896 + Pf1N1B4_652 0.12 -1.0 745,896 + Pf1N1B4_652 0.12 -1.0 745,896 + -1.0 745,896 + Pf1N1B4_652 0.12 -0.6 745,896 + Pf1N1B4_652 0.12 -1.6 745,897 - Pf1N1B4_652 0.13 -2.0 745,897 - Pf1N1B4_652 0.13 -2.9 745,897 - Pf1N1B4_652 0.13 -2.3 745,897 - Pf1N1B4_652 0.13 -2.0 745,897 - -1.0 745,897 - Pf1N1B4_652 0.13 -1.8 745,897 - Pf1N1B4_652 0.13 -2.6 745,897 - Pf1N1B4_652 0.13 -2.8 745,897 - Pf1N1B4_652 0.13 -2.0 745,897 - -1.0 745,897 - Pf1N1B4_652 0.13 -1.6 745,897 - Pf1N1B4_652 0.13 -2.0 745,897 - Pf1N1B4_652 0.13 -0.0 745,921 + Pf1N1B4_652 0.14 -2.6 745,921 + Pf1N1B4_652 0.14 -2.6 745,921 + Pf1N1B4_652 0.14 -0.0 745,921 + Pf1N1B4_652 0.14 +1.0 745,922 - -0.0 745,922 - Pf1N1B4_652 0.14 -2.0 745,922 - Pf1N1B4_652 0.14 -2.0 745,976 + Pf1N1B4_652 0.16 -2.8 746,113 + Pf1N1B4_652 0.23 -2.0 746,114 - Pf1N1B4_652 0.23 -2.6 746,114 - Pf1N1B4_652 0.23 -0.6 746,114 - Pf1N1B4_652 0.23 -2.6 746,114 - Pf1N1B4_652 0.23 -2.0 746,166 - Pf1N1B4_652 0.26 -2.0 746,260 + Pf1N1B4_652 0.30 -1.0 746,260 + Pf1N1B4_652 0.30 -2.0 746,261 - Pf1N1B4_652 0.30 -2.0 746,261 - Pf1N1B4_652 0.30 -1.0 746,261 - Pf1N1B4_652 0.30 -2.6 746,504 - Pf1N1B4_652 0.42 -1.6 746,504 - Pf1N1B4_652 0.42 -1.6 746,563 + Pf1N1B4_652 0.45 -0.6 746,563 + Pf1N1B4_652 0.45 -2.3 746,563 + Pf1N1B4_652 0.45 -1.8 746,563 + Pf1N1B4_652 0.45 -0.6 746,563 + Pf1N1B4_652 0.45 +1.0 746,564 - Pf1N1B4_652 0.45 -2.3 746,564 - Pf1N1B4_652 0.45 -3.6 746,564 - Pf1N1B4_652 0.45 -2.0 746,564 - Pf1N1B4_652 0.45 -2.3 746,567 + Pf1N1B4_652 0.45 +1.0 746,756 - Pf1N1B4_652 0.55 -1.0 746,916 + Pf1N1B4_652 0.63 -2.6 746,916 + Pf1N1B4_652 0.63 -2.9 746,916 + Pf1N1B4_652 0.63 -1.0 746,945 + Pf1N1B4_652 0.64 -1.8 746,945 + Pf1N1B4_652 0.64 -4.4 746,945 + Pf1N1B4_652 0.64 -1.0 746,945 + Pf1N1B4_652 0.64 -0.6 746,946 - Pf1N1B4_652 0.64 -1.0 747,037 + +1.6 747,038 - Pf1N1B4_652 0.69 -1.6 747,361 - Pf1N1B4_652 0.84 -1.3 747,396 + Pf1N1B4_652 0.86 -1.6 747,396 + Pf1N1B4_652 0.86 -1.0 747,474 + Pf1N1B4_652 0.90 -1.6 747,474 + Pf1N1B4_652 0.90 -2.3 747,474 + Pf1N1B4_652 0.90 -2.0 747,474 + Pf1N1B4_652 0.90 -1.0 747,474 + Pf1N1B4_652 0.90 -1.0 747,474 + Pf1N1B4_652 0.90 -0.0 747,475 - -2.8 747,475 - -1.0 747,541 + -3.2 747,541 + -1.3 747,676 + -0.8 747,705 + -0.6 747,706 - -0.2 747,706 - -0.4 747,854 + Pf1N1B4_653 0.30 -0.0 747,854 + Pf1N1B4_653 0.30 +1.0 747,854 + Pf1N1B4_653 0.30 -0.2 747,854 + Pf1N1B4_653 0.30 -1.6 747,854 + Pf1N1B4_653 0.30 -0.6 747,854 + Pf1N1B4_653 0.30 -0.3 747,854 + Pf1N1B4_653 0.30 -0.3 747,854 + Pf1N1B4_653 0.30 -1.6 747,854 + Pf1N1B4_653 0.30 -0.3 747,855 - Pf1N1B4_653 0.30 -0.4 747,855 - Pf1N1B4_653 0.30 +0.1 747,855 - Pf1N1B4_653 0.30 +0.4 747,855 - Pf1N1B4_653 0.30 -0.6 747,858 + Pf1N1B4_653 0.30 +2.0 747,858 + Pf1N1B4_653 0.30 -1.6 747,858 + Pf1N1B4_653 0.30 -1.0 747,858 + Pf1N1B4_653 0.30 +0.6 747,945 + Pf1N1B4_653 0.45 +0.2 747,946 - Pf1N1B4_653 0.46 -2.0 747,946 - Pf1N1B4_653 0.46 -0.6 748,072 + Pf1N1B4_653 0.67 +0.3 748,072 + Pf1N1B4_653 0.67 -0.0 748,072 + Pf1N1B4_653 0.67 -1.0 748,072 + Pf1N1B4_653 0.67 +2.8 748,155 + Pf1N1B4_653 0.81 +0.6 748,155 + Pf1N1B4_653 0.81 -1.4 748,155 + Pf1N1B4_653 0.81 -0.8 748,155 + Pf1N1B4_653 0.81 +0.1 748,155 + Pf1N1B4_653 0.81 -2.3 748,155 + Pf1N1B4_653 0.81 -0.0 748,155 + Pf1N1B4_653 0.81 -1.0 748,156 - Pf1N1B4_653 0.82 -0.0 748,156 - Pf1N1B4_653 0.82 -1.0 748,156 - Pf1N1B4_653 0.82 +0.5 748,156 - Pf1N1B4_653 0.82 +0.4 748,157 + Pf1N1B4_653 0.82 +0.6 748,157 + Pf1N1B4_653 0.82 -0.0 748,157 + Pf1N1B4_653 0.82 -0.2 748,158 - Pf1N1B4_653 0.82 -0.5 748,158 - Pf1N1B4_653 0.82 -1.8 748,260 + -1.0 748,320 + -0.0 748,508 - Pf1N1B4_654 0.12 -0.8 748,525 + Pf1N1B4_654 0.14 -2.6 748,525 + Pf1N1B4_654 0.14 -1.6 748,525 + Pf1N1B4_654 0.14 -0.0 748,526 - Pf1N1B4_654 0.14 -0.9 748,526 - Pf1N1B4_654 0.14 -1.6 748,526 - Pf1N1B4_654 0.14 -0.3 748,526 - Pf1N1B4_654 0.14 -0.6
Or see this region's nucleotide sequence