Experiment: Doxycycline hyclate 0.000025 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_2156 and Ac3H11_2157 overlap by 4 nucleotides Ac3H11_2157 and Ac3H11_2158 are separated by 514 nucleotides Ac3H11_2158 and Ac3H11_2159 overlap by 4 nucleotides Ac3H11_2159 and Ac3H11_2160 are separated by 166 nucleotides
Ac3H11_2156 - Two-component response regulator CreC, at 384,978 to 386,444
_2156
Ac3H11_2157 - hypothetical protein, at 386,441 to 386,605
_2157
Ac3H11_2158 - Inner membrane protein CreD, at 387,120 to 388,625
_2158
Ac3H11_2159 - hypothetical protein, at 388,622 to 388,990
_2159
Ac3H11_2160 - sensory box histidine kinase/response regulator, at 389,157 to 389,822
_2160
Position (kb) 387
388
389 Strain fitness (log2 ratio) -3
-2
-1
0
1
2
3
4 at 386.442 kb on + strand at 386.442 kb on + strand at 386.443 kb on - strand at 386.443 kb on - strand at 386.443 kb on - strand at 386.518 kb on - strand, within Ac3H11_2157 at 386.577 kb on - strand, within Ac3H11_2157 at 386.577 kb on - strand, within Ac3H11_2157 at 386.664 kb on + strand at 386.664 kb on + strand at 386.667 kb on + strand at 386.668 kb on - strand at 386.668 kb on - strand at 386.668 kb on - strand at 386.685 kb on + strand at 386.686 kb on - strand at 386.686 kb on - strand at 386.686 kb on - strand at 386.686 kb on - strand at 386.707 kb on + strand at 386.708 kb on - strand at 386.708 kb on - strand at 386.728 kb on + strand at 386.810 kb on + strand at 386.810 kb on + strand at 386.811 kb on - strand at 386.811 kb on - strand at 386.811 kb on - strand at 386.882 kb on + strand at 386.882 kb on + strand at 386.883 kb on - strand at 386.883 kb on - strand at 386.883 kb on - strand at 386.883 kb on - strand at 386.883 kb on - strand at 386.883 kb on - strand at 386.883 kb on - strand at 386.883 kb on - strand at 386.903 kb on + strand at 386.903 kb on + strand at 386.939 kb on + strand at 386.939 kb on + strand at 386.940 kb on - strand at 386.942 kb on - strand at 386.942 kb on - strand at 387.061 kb on + strand at 387.062 kb on - strand at 387.062 kb on - strand at 387.468 kb on + strand, within Ac3H11_2158 at 387.468 kb on + strand, within Ac3H11_2158 at 387.468 kb on + strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.469 kb on - strand, within Ac3H11_2158 at 387.669 kb on + strand, within Ac3H11_2158 at 387.669 kb on + strand, within Ac3H11_2158 at 387.669 kb on + strand, within Ac3H11_2158 at 387.669 kb on + strand, within Ac3H11_2158 at 387.670 kb on - strand, within Ac3H11_2158 at 387.670 kb on - strand, within Ac3H11_2158 at 387.670 kb on - strand, within Ac3H11_2158 at 387.670 kb on - strand, within Ac3H11_2158 at 387.670 kb on - strand, within Ac3H11_2158 at 388.056 kb on + strand, within Ac3H11_2158 at 388.056 kb on + strand, within Ac3H11_2158 at 388.057 kb on - strand, within Ac3H11_2158 at 388.083 kb on + strand, within Ac3H11_2158 at 388.084 kb on - strand, within Ac3H11_2158 at 388.167 kb on + strand, within Ac3H11_2158 at 388.168 kb on - strand, within Ac3H11_2158 at 388.168 kb on - strand, within Ac3H11_2158 at 388.248 kb on + strand, within Ac3H11_2158 at 388.287 kb on + strand, within Ac3H11_2158 at 388.288 kb on - strand, within Ac3H11_2158 at 388.288 kb on - strand, within Ac3H11_2158 at 388.290 kb on + strand, within Ac3H11_2158 at 388.290 kb on + strand, within Ac3H11_2158 at 388.290 kb on + strand, within Ac3H11_2158 at 388.290 kb on + strand, within Ac3H11_2158 at 388.291 kb on - strand, within Ac3H11_2158 at 388.291 kb on - strand, within Ac3H11_2158 at 388.291 kb on - strand, within Ac3H11_2158 at 388.291 kb on - strand, within Ac3H11_2158 at 388.325 kb on + strand, within Ac3H11_2158 at 388.326 kb on - strand, within Ac3H11_2158 at 388.356 kb on + strand, within Ac3H11_2158 at 388.356 kb on + strand, within Ac3H11_2158 at 388.356 kb on + strand, within Ac3H11_2158 at 388.356 kb on + strand, within Ac3H11_2158 at 388.356 kb on + strand, within Ac3H11_2158 at 388.356 kb on + strand, within Ac3H11_2158 at 388.357 kb on - strand, within Ac3H11_2158 at 388.357 kb on - strand, within Ac3H11_2158 at 388.357 kb on - strand, within Ac3H11_2158 at 388.368 kb on + strand, within Ac3H11_2158 at 388.368 kb on + strand, within Ac3H11_2158 at 388.368 kb on + strand, within Ac3H11_2158 at 388.368 kb on + strand, within Ac3H11_2158 at 388.368 kb on + strand, within Ac3H11_2158 at 388.368 kb on + strand, within Ac3H11_2158 at 388.368 kb on + strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.369 kb on - strand, within Ac3H11_2158 at 388.470 kb on + strand, within Ac3H11_2158 at 388.470 kb on + strand, within Ac3H11_2158 at 389.061 kb on + strand at 389.061 kb on + strand at 389.061 kb on + strand at 389.061 kb on + strand at 389.062 kb on - strand at 389.062 kb on - strand at 389.062 kb on - strand at 389.062 kb on - strand at 389.062 kb on - strand at 389.062 kb on - strand at 389.063 kb on + strand at 389.063 kb on + strand at 389.063 kb on + strand at 389.064 kb on - strand at 389.064 kb on - strand at 389.064 kb on - strand at 389.104 kb on - strand at 389.111 kb on - strand at 389.123 kb on + strand at 389.123 kb on + strand at 389.124 kb on - strand at 389.127 kb on + strand at 389.127 kb on + strand at 389.127 kb on + strand at 389.127 kb on + strand at 389.127 kb on + strand at 389.127 kb on + strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.128 kb on - strand at 389.132 kb on - strand at 389.132 kb on - strand at 389.137 kb on + strand at 389.137 kb on + strand at 389.138 kb on - strand at 389.150 kb on + strand at 389.150 kb on + strand at 389.150 kb on + strand at 389.150 kb on + strand at 389.150 kb on + strand at 389.151 kb on - strand at 389.151 kb on - strand at 389.151 kb on - strand at 389.151 kb on - strand at 389.158 kb on + strand at 389.158 kb on + strand at 389.158 kb on + strand at 389.158 kb on + strand at 389.158 kb on + strand at 389.159 kb on - strand at 389.200 kb on + strand at 389.201 kb on - strand at 389.201 kb on - strand at 389.201 kb on - strand at 389.201 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction Doxycycline hyclate 0.000025 mg/ml remove 386,442 + -0.8 386,442 + -2.2 386,443 - +0.0 386,443 - +1.5 386,443 - +0.3 386,518 - Ac3H11_2157 0.47 -0.5 386,577 - Ac3H11_2157 0.82 +0.0 386,577 - Ac3H11_2157 0.82 +1.3 386,664 + -1.4 386,664 + -0.9 386,667 + -0.7 386,668 - -0.5 386,668 - +0.5 386,668 - -1.3 386,685 + +0.8 386,686 - -0.1 386,686 - -0.3 386,686 - +0.6 386,686 - -0.3 386,707 + +3.8 386,708 - -0.0 386,708 - -0.0 386,728 + -0.2 386,810 + +0.5 386,810 + +0.3 386,811 - -0.8 386,811 - +0.1 386,811 - +0.3 386,882 + +1.1 386,882 + -0.7 386,883 - -0.1 386,883 - -0.9 386,883 - -0.2 386,883 - -0.2 386,883 - -0.0 386,883 - -0.6 386,883 - -0.5 386,883 - +0.3 386,903 + -0.7 386,903 + +0.4 386,939 + -1.1 386,939 + +1.3 386,940 - +0.4 386,942 - +0.3 386,942 - -1.5 387,061 + +0.5 387,062 - -1.0 387,062 - -0.9 387,468 + Ac3H11_2158 0.23 -0.1 387,468 + Ac3H11_2158 0.23 -0.1 387,468 + Ac3H11_2158 0.23 +0.4 387,469 - Ac3H11_2158 0.23 -0.2 387,469 - Ac3H11_2158 0.23 +0.6 387,469 - Ac3H11_2158 0.23 -0.5 387,469 - Ac3H11_2158 0.23 -0.1 387,469 - Ac3H11_2158 0.23 -0.1 387,469 - Ac3H11_2158 0.23 -0.4 387,469 - Ac3H11_2158 0.23 -0.5 387,469 - Ac3H11_2158 0.23 -0.3 387,669 + Ac3H11_2158 0.36 +0.0 387,669 + Ac3H11_2158 0.36 -0.5 387,669 + Ac3H11_2158 0.36 -0.9 387,669 + Ac3H11_2158 0.36 -0.5 387,670 - Ac3H11_2158 0.37 +1.5 387,670 - Ac3H11_2158 0.37 -0.2 387,670 - Ac3H11_2158 0.37 -0.8 387,670 - Ac3H11_2158 0.37 +0.3 387,670 - Ac3H11_2158 0.37 -0.5 388,056 + Ac3H11_2158 0.62 -0.4 388,056 + Ac3H11_2158 0.62 -1.1 388,057 - Ac3H11_2158 0.62 -0.5 388,083 + Ac3H11_2158 0.64 +0.2 388,084 - Ac3H11_2158 0.64 -0.9 388,167 + Ac3H11_2158 0.70 +0.5 388,168 - Ac3H11_2158 0.70 +0.5 388,168 - Ac3H11_2158 0.70 -0.8 388,248 + Ac3H11_2158 0.75 +0.1 388,287 + Ac3H11_2158 0.77 +0.4 388,288 - Ac3H11_2158 0.78 -1.0 388,288 - Ac3H11_2158 0.78 +0.5 388,290 + Ac3H11_2158 0.78 -0.5 388,290 + Ac3H11_2158 0.78 -0.3 388,290 + Ac3H11_2158 0.78 +0.3 388,290 + Ac3H11_2158 0.78 -0.7 388,291 - Ac3H11_2158 0.78 -1.1 388,291 - Ac3H11_2158 0.78 -0.9 388,291 - Ac3H11_2158 0.78 -0.4 388,291 - Ac3H11_2158 0.78 -1.0 388,325 + Ac3H11_2158 0.80 -0.1 388,326 - Ac3H11_2158 0.80 -0.3 388,356 + Ac3H11_2158 0.82 -0.6 388,356 + Ac3H11_2158 0.82 +0.3 388,356 + Ac3H11_2158 0.82 -0.0 388,356 + Ac3H11_2158 0.82 -2.9 388,356 + Ac3H11_2158 0.82 +0.5 388,356 + Ac3H11_2158 0.82 -0.4 388,357 - Ac3H11_2158 0.82 -0.2 388,357 - Ac3H11_2158 0.82 +0.8 388,357 - Ac3H11_2158 0.82 +0.3 388,368 + Ac3H11_2158 0.83 +0.3 388,368 + Ac3H11_2158 0.83 -0.7 388,368 + Ac3H11_2158 0.83 +1.0 388,368 + Ac3H11_2158 0.83 -0.5 388,368 + Ac3H11_2158 0.83 +0.5 388,368 + Ac3H11_2158 0.83 +0.3 388,368 + Ac3H11_2158 0.83 +0.0 388,369 - Ac3H11_2158 0.83 +0.9 388,369 - Ac3H11_2158 0.83 -0.2 388,369 - Ac3H11_2158 0.83 -0.5 388,369 - Ac3H11_2158 0.83 +0.0 388,369 - Ac3H11_2158 0.83 -1.2 388,369 - Ac3H11_2158 0.83 -0.3 388,369 - Ac3H11_2158 0.83 +0.0 388,369 - Ac3H11_2158 0.83 -0.1 388,470 + Ac3H11_2158 0.90 -0.3 388,470 + Ac3H11_2158 0.90 -0.7 389,061 + -0.4 389,061 + -1.6 389,061 + -1.1 389,061 + +0.1 389,062 - -0.9 389,062 - +0.6 389,062 - -1.1 389,062 - -0.7 389,062 - +1.2 389,062 - -1.2 389,063 + +0.5 389,063 + -0.9 389,063 + -0.3 389,064 - -0.2 389,064 - -1.0 389,064 - -1.8 389,104 - -1.0 389,111 - -0.6 389,123 + +0.9 389,123 + -0.6 389,124 - +0.7 389,127 + -1.0 389,127 + -1.5 389,127 + -0.7 389,127 + -0.1 389,127 + +0.7 389,127 + -0.5 389,128 - +0.0 389,128 - -0.2 389,128 - -1.4 389,128 - -0.1 389,128 - -1.9 389,128 - -1.7 389,128 - -1.5 389,128 - -0.8 389,128 - -0.7 389,128 - -0.4 389,128 - +0.9 389,132 - -0.8 389,132 - +1.0 389,137 + -0.1 389,137 + -0.9 389,138 - -1.1 389,150 + -0.6 389,150 + +0.3 389,150 + -0.7 389,150 + -1.9 389,150 + +0.5 389,151 - -0.1 389,151 - -0.8 389,151 - -0.6 389,151 - -1.1 389,158 + -0.7 389,158 + -0.5 389,158 + -0.2 389,158 + -0.5 389,158 + +0.0 389,159 - -0.4 389,200 + -1.4 389,201 - +0.7 389,201 - -0.1 389,201 - -0.2 389,201 - +0.5
Or see this region's nucleotide sequence