Experiment: Doxycycline hyclate 0.000025 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_1156 and Ac3H11_1157 are separated by 142 nucleotides Ac3H11_1157 and Ac3H11_1158 are separated by 88 nucleotides Ac3H11_1158 and Ac3H11_1159 are separated by 133 nucleotides
Ac3H11_1156 - Tryptophan 2,3-dioxygenase (EC 1.13.11.11), at 108,323 to 109,219
_1156
Ac3H11_1157 - Kynureninase (EC 3.7.1.3), at 109,362 to 110,672
_1157
Ac3H11_1158 - Kynurenine formamidase, bacterial (EC 3.5.1.9), at 110,761 to 111,414
_1158
Ac3H11_1159 - Sensory histidine kinase QseC, at 111,548 to 112,969
_1159
Position (kb)
109
110
111 Strain fitness (log2 ratio)
-2
-1
0
1
2 at 108.387 kb on + strand at 108.387 kb on + strand at 108.388 kb on - strand at 108.525 kb on + strand, within Ac3H11_1156 at 108.525 kb on + strand, within Ac3H11_1156 at 108.544 kb on - strand, within Ac3H11_1156 at 108.583 kb on + strand, within Ac3H11_1156 at 108.585 kb on + strand, within Ac3H11_1156 at 108.585 kb on + strand, within Ac3H11_1156 at 108.585 kb on + strand, within Ac3H11_1156 at 108.585 kb on + strand, within Ac3H11_1156 at 108.585 kb on + strand, within Ac3H11_1156 at 108.585 kb on + strand, within Ac3H11_1156 at 108.586 kb on - strand, within Ac3H11_1156 at 108.586 kb on - strand, within Ac3H11_1156 at 108.586 kb on - strand, within Ac3H11_1156 at 108.586 kb on - strand, within Ac3H11_1156 at 108.586 kb on - strand, within Ac3H11_1156 at 108.667 kb on - strand, within Ac3H11_1156 at 108.786 kb on + strand, within Ac3H11_1156 at 108.786 kb on + strand, within Ac3H11_1156 at 108.786 kb on + strand, within Ac3H11_1156 at 108.786 kb on + strand, within Ac3H11_1156 at 108.787 kb on - strand, within Ac3H11_1156 at 108.787 kb on - strand, within Ac3H11_1156 at 108.816 kb on + strand, within Ac3H11_1156 at 108.816 kb on + strand, within Ac3H11_1156 at 108.835 kb on - strand, within Ac3H11_1156 at 109.095 kb on + strand, within Ac3H11_1156 at 109.095 kb on + strand, within Ac3H11_1156 at 109.096 kb on - strand, within Ac3H11_1156 at 109.105 kb on - strand, within Ac3H11_1156 at 109.340 kb on + strand at 109.360 kb on + strand at 109.464 kb on + strand at 109.464 kb on + strand at 109.465 kb on - strand at 109.465 kb on - strand at 109.468 kb on + strand at 109.468 kb on + strand at 109.469 kb on - strand at 109.478 kb on + strand at 109.580 kb on - strand, within Ac3H11_1157 at 109.580 kb on - strand, within Ac3H11_1157 at 109.846 kb on + strand, within Ac3H11_1157 at 109.873 kb on + strand, within Ac3H11_1157 at 109.873 kb on + strand, within Ac3H11_1157 at 109.873 kb on + strand, within Ac3H11_1157 at 109.996 kb on + strand, within Ac3H11_1157 at 109.997 kb on - strand, within Ac3H11_1157 at 109.997 kb on - strand, within Ac3H11_1157 at 110.152 kb on + strand, within Ac3H11_1157 at 110.152 kb on + strand, within Ac3H11_1157 at 110.152 kb on + strand, within Ac3H11_1157 at 110.269 kb on + strand, within Ac3H11_1157 at 110.269 kb on + strand, within Ac3H11_1157 at 110.270 kb on - strand, within Ac3H11_1157 at 110.270 kb on - strand, within Ac3H11_1157 at 110.270 kb on - strand, within Ac3H11_1157 at 110.270 kb on - strand, within Ac3H11_1157 at 110.270 kb on - strand, within Ac3H11_1157 at 110.365 kb on + strand, within Ac3H11_1157 at 110.365 kb on + strand, within Ac3H11_1157 at 110.365 kb on + strand, within Ac3H11_1157 at 110.366 kb on - strand, within Ac3H11_1157 at 110.366 kb on - strand, within Ac3H11_1157 at 110.366 kb on - strand, within Ac3H11_1157 at 110.578 kb on + strand at 110.578 kb on + strand at 110.579 kb on - strand at 110.710 kb on + strand at 110.762 kb on + strand at 110.762 kb on + strand at 110.762 kb on + strand at 110.762 kb on + strand at 110.763 kb on - strand at 110.763 kb on - strand at 110.763 kb on - strand at 111.012 kb on - strand, within Ac3H11_1158 at 111.056 kb on + strand, within Ac3H11_1158 at 111.056 kb on + strand, within Ac3H11_1158 at 111.056 kb on + strand, within Ac3H11_1158 at 111.057 kb on - strand, within Ac3H11_1158 at 111.057 kb on - strand, within Ac3H11_1158 at 111.057 kb on - strand, within Ac3H11_1158 at 111.057 kb on - strand, within Ac3H11_1158 at 111.057 kb on - strand, within Ac3H11_1158 at 111.215 kb on + strand, within Ac3H11_1158 at 111.215 kb on + strand, within Ac3H11_1158 at 111.216 kb on - strand, within Ac3H11_1158 at 111.216 kb on - strand, within Ac3H11_1158 at 111.216 kb on - strand, within Ac3H11_1158 at 111.320 kb on + strand, within Ac3H11_1158 at 111.320 kb on + strand, within Ac3H11_1158 at 111.491 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction Doxycycline hyclate 0.000025 mg/ml remove 108,387 + +0.3 108,387 + +0.4 108,388 - +0.4 108,525 + Ac3H11_1156 0.23 -0.7 108,525 + Ac3H11_1156 0.23 +0.9 108,544 - Ac3H11_1156 0.25 -0.9 108,583 + Ac3H11_1156 0.29 -0.1 108,585 + Ac3H11_1156 0.29 +0.9 108,585 + Ac3H11_1156 0.29 +1.2 108,585 + Ac3H11_1156 0.29 -0.3 108,585 + Ac3H11_1156 0.29 -0.3 108,585 + Ac3H11_1156 0.29 -0.8 108,585 + Ac3H11_1156 0.29 -0.1 108,586 - Ac3H11_1156 0.29 +0.2 108,586 - Ac3H11_1156 0.29 +1.2 108,586 - Ac3H11_1156 0.29 -0.0 108,586 - Ac3H11_1156 0.29 +0.5 108,586 - Ac3H11_1156 0.29 +0.2 108,667 - Ac3H11_1156 0.38 +0.6 108,786 + Ac3H11_1156 0.52 -0.6 108,786 + Ac3H11_1156 0.52 -0.9 108,786 + Ac3H11_1156 0.52 -1.0 108,786 + Ac3H11_1156 0.52 +1.3 108,787 - Ac3H11_1156 0.52 +0.4 108,787 - Ac3H11_1156 0.52 +0.7 108,816 + Ac3H11_1156 0.55 +1.3 108,816 + Ac3H11_1156 0.55 +0.1 108,835 - Ac3H11_1156 0.57 -0.9 109,095 + Ac3H11_1156 0.86 -0.5 109,095 + Ac3H11_1156 0.86 +0.3 109,096 - Ac3H11_1156 0.86 -0.5 109,105 - Ac3H11_1156 0.87 +1.7 109,340 + +0.4 109,360 + +0.2 109,464 + -0.1 109,464 + +1.0 109,465 - +0.3 109,465 - -0.6 109,468 + +1.7 109,468 + -0.4 109,469 - +0.5 109,478 + -0.1 109,580 - Ac3H11_1157 0.17 +0.4 109,580 - Ac3H11_1157 0.17 +0.8 109,846 + Ac3H11_1157 0.37 +0.0 109,873 + Ac3H11_1157 0.39 -0.0 109,873 + Ac3H11_1157 0.39 +0.5 109,873 + Ac3H11_1157 0.39 +0.6 109,996 + Ac3H11_1157 0.48 +0.6 109,997 - Ac3H11_1157 0.48 -0.4 109,997 - Ac3H11_1157 0.48 +0.4 110,152 + Ac3H11_1157 0.60 -0.0 110,152 + Ac3H11_1157 0.60 +1.6 110,152 + Ac3H11_1157 0.60 +0.1 110,269 + Ac3H11_1157 0.69 -1.5 110,269 + Ac3H11_1157 0.69 -0.4 110,270 - Ac3H11_1157 0.69 +1.2 110,270 - Ac3H11_1157 0.69 -1.1 110,270 - Ac3H11_1157 0.69 -0.2 110,270 - Ac3H11_1157 0.69 -0.5 110,270 - Ac3H11_1157 0.69 +1.1 110,365 + Ac3H11_1157 0.77 -0.1 110,365 + Ac3H11_1157 0.77 -0.4 110,365 + Ac3H11_1157 0.77 +0.8 110,366 - Ac3H11_1157 0.77 -0.2 110,366 - Ac3H11_1157 0.77 +0.4 110,366 - Ac3H11_1157 0.77 +0.2 110,578 + -0.4 110,578 + -1.1 110,579 - +0.2 110,710 + +0.4 110,762 + +0.8 110,762 + +0.2 110,762 + +1.0 110,762 + -2.7 110,763 - +2.0 110,763 - +1.2 110,763 - -0.4 111,012 - Ac3H11_1158 0.38 +0.3 111,056 + Ac3H11_1158 0.45 +0.4 111,056 + Ac3H11_1158 0.45 +0.3 111,056 + Ac3H11_1158 0.45 -2.4 111,057 - Ac3H11_1158 0.45 +0.6 111,057 - Ac3H11_1158 0.45 +0.4 111,057 - Ac3H11_1158 0.45 -1.9 111,057 - Ac3H11_1158 0.45 +2.0 111,057 - Ac3H11_1158 0.45 -1.4 111,215 + Ac3H11_1158 0.69 -0.2 111,215 + Ac3H11_1158 0.69 -0.2 111,216 - Ac3H11_1158 0.70 +0.8 111,216 - Ac3H11_1158 0.70 +1.3 111,216 - Ac3H11_1158 0.70 -1.1 111,320 + Ac3H11_1158 0.85 +0.8 111,320 + Ac3H11_1158 0.85 +0.6 111,491 + +0.4
Or see this region's nucleotide sequence