Experiment: D-Cycloserine 0.05 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Ac3H11_919 and Ac3H11_920 are separated by 131 nucleotides Ac3H11_920 and Ac3H11_921 are separated by 128 nucleotides Ac3H11_921 and Ac3H11_922 are separated by 321 nucleotides
Ac3H11_919 - Transcriptional regulator, LysR family, at 32,465 to 33,412
_919
Ac3H11_920 - FMN-dependent NADH-azoreductase, at 33,544 to 34,188
_920
Ac3H11_921 - diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s), at 34,317 to 36,647
_921
Ac3H11_922 - Mobile element protein, at 36,969 to 37,949
_922
Position (kb)
34
35
36
37 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2 at 33.387 kb on + strand at 33.387 kb on + strand at 33.387 kb on + strand at 33.387 kb on + strand at 33.387 kb on + strand at 33.387 kb on + strand at 33.387 kb on + strand at 33.388 kb on - strand at 33.388 kb on - strand at 33.388 kb on - strand at 33.388 kb on - strand at 33.412 kb on + strand at 33.412 kb on + strand at 33.412 kb on + strand at 33.412 kb on + strand at 33.413 kb on - strand at 33.413 kb on - strand at 33.413 kb on - strand at 33.413 kb on - strand at 33.433 kb on + strand at 33.658 kb on + strand, within Ac3H11_920 at 33.658 kb on + strand, within Ac3H11_920 at 33.658 kb on + strand, within Ac3H11_920 at 33.826 kb on + strand, within Ac3H11_920 at 33.826 kb on + strand, within Ac3H11_920 at 33.826 kb on + strand, within Ac3H11_920 at 33.826 kb on + strand, within Ac3H11_920 at 33.826 kb on + strand, within Ac3H11_920 at 33.827 kb on - strand, within Ac3H11_920 at 33.827 kb on - strand, within Ac3H11_920 at 33.827 kb on - strand, within Ac3H11_920 at 33.898 kb on + strand, within Ac3H11_920 at 33.898 kb on + strand, within Ac3H11_920 at 33.899 kb on - strand, within Ac3H11_920 at 33.970 kb on + strand, within Ac3H11_920 at 33.970 kb on + strand, within Ac3H11_920 at 33.970 kb on + strand, within Ac3H11_920 at 33.971 kb on - strand, within Ac3H11_920 at 34.015 kb on + strand, within Ac3H11_920 at 34.015 kb on + strand, within Ac3H11_920 at 34.015 kb on + strand, within Ac3H11_920 at 34.016 kb on - strand, within Ac3H11_920 at 34.016 kb on - strand, within Ac3H11_920 at 34.016 kb on - strand, within Ac3H11_920 at 34.016 kb on - strand, within Ac3H11_920 at 34.172 kb on + strand at 34.173 kb on - strand at 34.173 kb on - strand at 34.186 kb on + strand at 34.186 kb on + strand at 34.186 kb on + strand at 34.186 kb on + strand at 34.187 kb on - strand at 34.187 kb on - strand at 34.187 kb on - strand at 34.319 kb on - strand at 34.477 kb on - strand at 34.702 kb on + strand, within Ac3H11_921 at 34.702 kb on + strand, within Ac3H11_921 at 34.702 kb on + strand, within Ac3H11_921 at 34.702 kb on + strand, within Ac3H11_921 at 34.703 kb on - strand, within Ac3H11_921 at 34.703 kb on - strand, within Ac3H11_921 at 34.703 kb on - strand, within Ac3H11_921 at 34.703 kb on - strand, within Ac3H11_921 at 34.703 kb on - strand, within Ac3H11_921 at 34.703 kb on - strand, within Ac3H11_921 at 34.703 kb on - strand, within Ac3H11_921 at 35.050 kb on + strand, within Ac3H11_921 at 35.050 kb on + strand, within Ac3H11_921 at 35.050 kb on + strand, within Ac3H11_921 at 35.051 kb on - strand, within Ac3H11_921 at 35.143 kb on + strand, within Ac3H11_921 at 35.144 kb on - strand, within Ac3H11_921 at 35.269 kb on + strand, within Ac3H11_921 at 35.269 kb on + strand, within Ac3H11_921 at 35.269 kb on + strand, within Ac3H11_921 at 35.270 kb on - strand, within Ac3H11_921 at 35.270 kb on - strand, within Ac3H11_921 at 35.270 kb on - strand, within Ac3H11_921 at 35.270 kb on - strand, within Ac3H11_921 at 35.270 kb on - strand, within Ac3H11_921 at 35.483 kb on - strand, within Ac3H11_921 at 35.483 kb on - strand, within Ac3H11_921 at 35.603 kb on - strand, within Ac3H11_921 at 35.651 kb on - strand, within Ac3H11_921 at 35.863 kb on + strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.864 kb on - strand, within Ac3H11_921 at 35.894 kb on - strand, within Ac3H11_921 at 36.139 kb on + strand, within Ac3H11_921 at 36.139 kb on + strand, within Ac3H11_921 at 36.140 kb on - strand, within Ac3H11_921 at 36.140 kb on - strand, within Ac3H11_921 at 36.140 kb on - strand, within Ac3H11_921 at 36.152 kb on - strand, within Ac3H11_921 at 36.206 kb on - strand, within Ac3H11_921 at 36.206 kb on - strand, within Ac3H11_921 at 36.206 kb on - strand, within Ac3H11_921 at 36.269 kb on - strand, within Ac3H11_921 at 36.738 kb on - strand at 36.738 kb on - strand at 36.765 kb on - strand at 36.774 kb on - strand at 36.784 kb on + strand at 36.797 kb on + strand at 36.901 kb on - strand at 36.901 kb on - strand at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.108 kb on + strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.109 kb on - strand, within Ac3H11_922 at 37.132 kb on + strand, within Ac3H11_922 at 37.132 kb on + strand, within Ac3H11_922 at 37.133 kb on - strand, within Ac3H11_922 at 37.133 kb on - strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.159 kb on + strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.160 kb on - strand, within Ac3H11_922 at 37.173 kb on + strand, within Ac3H11_922 at 37.173 kb on + strand, within Ac3H11_922 at 37.173 kb on + strand, within Ac3H11_922 at 37.173 kb on + strand, within Ac3H11_922 at 37.173 kb on + strand, within Ac3H11_922 at 37.174 kb on - strand, within Ac3H11_922 at 37.174 kb on - strand, within Ac3H11_922 at 37.174 kb on - strand, within Ac3H11_922 at 37.174 kb on - strand, within Ac3H11_922 at 37.174 kb on - strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.372 kb on + strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.373 kb on - strand, within Ac3H11_922 at 37.404 kb on + strand, within Ac3H11_922 at 37.404 kb on + strand, within Ac3H11_922 at 37.404 kb on + strand, within Ac3H11_922 at 37.404 kb on + strand, within Ac3H11_922 at 37.405 kb on - strand, within Ac3H11_922 at 37.405 kb on - strand, within Ac3H11_922 at 37.405 kb on - strand, within Ac3H11_922 at 37.405 kb on - strand, within Ac3H11_922 at 37.405 kb on - strand, within Ac3H11_922 at 37.603 kb on + strand, within Ac3H11_922 at 37.603 kb on + strand, within Ac3H11_922 at 37.603 kb on + strand, within Ac3H11_922 at 37.603 kb on + strand, within Ac3H11_922 at 37.603 kb on + strand, within Ac3H11_922 at 37.603 kb on + strand, within Ac3H11_922 at 37.604 kb on - strand, within Ac3H11_922
Per-strain Table
Position Strand Gene LocusTag Fraction D-Cycloserine 0.05 mg/ml remove 33,387 + +0.9 33,387 + -1.9 33,387 + +0.7 33,387 + -0.6 33,387 + -2.9 33,387 + +2.4 33,387 + +0.3 33,388 - +0.3 33,388 - -0.5 33,388 - +1.1 33,388 - +2.4 33,412 + +0.7 33,412 + -1.3 33,412 + -0.8 33,412 + +0.6 33,413 - -0.7 33,413 - -0.6 33,413 - +0.7 33,413 - -0.3 33,433 + +0.8 33,658 + Ac3H11_920 0.18 -1.3 33,658 + Ac3H11_920 0.18 -1.1 33,658 + Ac3H11_920 0.18 +1.1 33,826 + Ac3H11_920 0.44 -1.9 33,826 + Ac3H11_920 0.44 +1.0 33,826 + Ac3H11_920 0.44 +0.7 33,826 + Ac3H11_920 0.44 +1.3 33,826 + Ac3H11_920 0.44 -0.2 33,827 - Ac3H11_920 0.44 +0.3 33,827 - Ac3H11_920 0.44 +1.0 33,827 - Ac3H11_920 0.44 +0.0 33,898 + Ac3H11_920 0.55 -1.3 33,898 + Ac3H11_920 0.55 -0.0 33,899 - Ac3H11_920 0.55 +0.7 33,970 + Ac3H11_920 0.66 +0.2 33,970 + Ac3H11_920 0.66 +0.3 33,970 + Ac3H11_920 0.66 +0.0 33,971 - Ac3H11_920 0.66 +0.2 34,015 + Ac3H11_920 0.73 -0.2 34,015 + Ac3H11_920 0.73 +1.3 34,015 + Ac3H11_920 0.73 +0.7 34,016 - Ac3H11_920 0.73 -1.2 34,016 - Ac3H11_920 0.73 -1.3 34,016 - Ac3H11_920 0.73 +1.0 34,016 - Ac3H11_920 0.73 -0.5 34,172 + +0.1 34,173 - +0.2 34,173 - +0.0 34,186 + +0.8 34,186 + +0.0 34,186 + -0.1 34,186 + -1.1 34,187 - +0.1 34,187 - -0.7 34,187 - -1.9 34,319 - -0.3 34,477 - +0.9 34,702 + Ac3H11_921 0.17 +0.5 34,702 + Ac3H11_921 0.17 -0.9 34,702 + Ac3H11_921 0.17 +0.5 34,702 + Ac3H11_921 0.17 -1.8 34,703 - Ac3H11_921 0.17 -0.6 34,703 - Ac3H11_921 0.17 +0.1 34,703 - Ac3H11_921 0.17 +0.9 34,703 - Ac3H11_921 0.17 -0.0 34,703 - Ac3H11_921 0.17 +2.1 34,703 - Ac3H11_921 0.17 +0.8 34,703 - Ac3H11_921 0.17 +0.2 35,050 + Ac3H11_921 0.31 +0.4 35,050 + Ac3H11_921 0.31 +0.7 35,050 + Ac3H11_921 0.31 -0.2 35,051 - Ac3H11_921 0.31 -0.4 35,143 + Ac3H11_921 0.35 +2.6 35,144 - Ac3H11_921 0.35 -0.4 35,269 + Ac3H11_921 0.41 +1.3 35,269 + Ac3H11_921 0.41 -0.6 35,269 + Ac3H11_921 0.41 -1.0 35,270 - Ac3H11_921 0.41 -0.2 35,270 - Ac3H11_921 0.41 +0.3 35,270 - Ac3H11_921 0.41 -0.1 35,270 - Ac3H11_921 0.41 -0.4 35,270 - Ac3H11_921 0.41 +0.4 35,483 - Ac3H11_921 0.50 +1.2 35,483 - Ac3H11_921 0.50 -1.4 35,603 - Ac3H11_921 0.55 +1.1 35,651 - Ac3H11_921 0.57 -0.8 35,863 + Ac3H11_921 0.66 +0.5 35,864 - Ac3H11_921 0.66 +0.3 35,864 - Ac3H11_921 0.66 +1.4 35,864 - Ac3H11_921 0.66 -0.9 35,864 - Ac3H11_921 0.66 -1.3 35,864 - Ac3H11_921 0.66 -1.3 35,864 - Ac3H11_921 0.66 -1.2 35,864 - Ac3H11_921 0.66 +0.2 35,864 - Ac3H11_921 0.66 -1.1 35,864 - Ac3H11_921 0.66 +1.1 35,864 - Ac3H11_921 0.66 -2.3 35,864 - Ac3H11_921 0.66 -0.5 35,864 - Ac3H11_921 0.66 -0.7 35,864 - Ac3H11_921 0.66 +0.7 35,894 - Ac3H11_921 0.68 +0.1 36,139 + Ac3H11_921 0.78 -1.9 36,139 + Ac3H11_921 0.78 +0.1 36,140 - Ac3H11_921 0.78 +0.2 36,140 - Ac3H11_921 0.78 +1.0 36,140 - Ac3H11_921 0.78 -1.4 36,152 - Ac3H11_921 0.79 -1.3 36,206 - Ac3H11_921 0.81 -0.1 36,206 - Ac3H11_921 0.81 +0.6 36,206 - Ac3H11_921 0.81 +1.7 36,269 - Ac3H11_921 0.84 -0.1 36,738 - +1.1 36,738 - +1.3 36,765 - -0.9 36,774 - -0.5 36,784 + -1.4 36,797 + -0.3 36,901 - +0.9 36,901 - -0.3 37,108 + Ac3H11_922 0.14 +0.5 37,108 + Ac3H11_922 0.14 +0.0 37,108 + Ac3H11_922 0.14 +1.4 37,108 + Ac3H11_922 0.14 -0.4 37,108 + Ac3H11_922 0.14 +0.9 37,108 + Ac3H11_922 0.14 +1.2 37,108 + Ac3H11_922 0.14 +0.2 37,108 + Ac3H11_922 0.14 +0.6 37,108 + Ac3H11_922 0.14 +0.6 37,108 + Ac3H11_922 0.14 +1.4 37,108 + Ac3H11_922 0.14 +0.1 37,108 + Ac3H11_922 0.14 -0.5 37,108 + Ac3H11_922 0.14 -1.0 37,109 - Ac3H11_922 0.14 -1.5 37,109 - Ac3H11_922 0.14 -1.3 37,109 - Ac3H11_922 0.14 -0.3 37,109 - Ac3H11_922 0.14 +0.7 37,109 - Ac3H11_922 0.14 -0.0 37,109 - Ac3H11_922 0.14 -0.6 37,109 - Ac3H11_922 0.14 +0.8 37,109 - Ac3H11_922 0.14 +0.2 37,109 - Ac3H11_922 0.14 -1.0 37,109 - Ac3H11_922 0.14 -0.2 37,132 + Ac3H11_922 0.17 -2.0 37,132 + Ac3H11_922 0.17 -0.9 37,133 - Ac3H11_922 0.17 -0.6 37,133 - Ac3H11_922 0.17 -1.4 37,159 + Ac3H11_922 0.19 -1.7 37,159 + Ac3H11_922 0.19 -0.1 37,159 + Ac3H11_922 0.19 -0.3 37,159 + Ac3H11_922 0.19 +0.8 37,159 + Ac3H11_922 0.19 +0.1 37,159 + Ac3H11_922 0.19 -0.2 37,159 + Ac3H11_922 0.19 -1.2 37,159 + Ac3H11_922 0.19 -0.3 37,159 + Ac3H11_922 0.19 -0.9 37,159 + Ac3H11_922 0.19 -0.4 37,159 + Ac3H11_922 0.19 -0.7 37,159 + Ac3H11_922 0.19 +0.5 37,159 + Ac3H11_922 0.19 -1.2 37,160 - Ac3H11_922 0.19 +1.0 37,160 - Ac3H11_922 0.19 +0.4 37,160 - Ac3H11_922 0.19 -0.6 37,160 - Ac3H11_922 0.19 +0.2 37,160 - Ac3H11_922 0.19 -0.4 37,160 - Ac3H11_922 0.19 -0.9 37,160 - Ac3H11_922 0.19 +0.0 37,160 - Ac3H11_922 0.19 -1.7 37,160 - Ac3H11_922 0.19 -2.3 37,160 - Ac3H11_922 0.19 +0.3 37,160 - Ac3H11_922 0.19 -1.0 37,160 - Ac3H11_922 0.19 -0.8 37,160 - Ac3H11_922 0.19 -1.2 37,160 - Ac3H11_922 0.19 -1.2 37,160 - Ac3H11_922 0.19 -0.8 37,173 + Ac3H11_922 0.21 -0.3 37,173 + Ac3H11_922 0.21 -0.8 37,173 + Ac3H11_922 0.21 +0.1 37,173 + Ac3H11_922 0.21 +1.1 37,173 + Ac3H11_922 0.21 -0.4 37,174 - Ac3H11_922 0.21 -0.2 37,174 - Ac3H11_922 0.21 +0.8 37,174 - Ac3H11_922 0.21 -1.7 37,174 - Ac3H11_922 0.21 -1.2 37,174 - Ac3H11_922 0.21 +0.2 37,372 + Ac3H11_922 0.41 +1.7 37,372 + Ac3H11_922 0.41 +0.6 37,372 + Ac3H11_922 0.41 -1.4 37,372 + Ac3H11_922 0.41 +0.4 37,372 + Ac3H11_922 0.41 -1.0 37,372 + Ac3H11_922 0.41 +1.1 37,372 + Ac3H11_922 0.41 -0.0 37,372 + Ac3H11_922 0.41 -0.2 37,372 + Ac3H11_922 0.41 -0.1 37,372 + Ac3H11_922 0.41 +0.1 37,372 + Ac3H11_922 0.41 -0.6 37,372 + Ac3H11_922 0.41 +0.8 37,373 - Ac3H11_922 0.41 -1.3 37,373 - Ac3H11_922 0.41 -0.4 37,373 - Ac3H11_922 0.41 +0.2 37,373 - Ac3H11_922 0.41 +0.8 37,373 - Ac3H11_922 0.41 -0.7 37,373 - Ac3H11_922 0.41 -0.6 37,373 - Ac3H11_922 0.41 -1.0 37,373 - Ac3H11_922 0.41 +0.1 37,373 - Ac3H11_922 0.41 -0.3 37,373 - Ac3H11_922 0.41 -0.6 37,373 - Ac3H11_922 0.41 +0.2 37,373 - Ac3H11_922 0.41 +0.1 37,404 + Ac3H11_922 0.44 +1.0 37,404 + Ac3H11_922 0.44 +2.5 37,404 + Ac3H11_922 0.44 -1.1 37,404 + Ac3H11_922 0.44 +1.3 37,405 - Ac3H11_922 0.44 -0.7 37,405 - Ac3H11_922 0.44 -0.7 37,405 - Ac3H11_922 0.44 -0.2 37,405 - Ac3H11_922 0.44 -0.1 37,405 - Ac3H11_922 0.44 +0.0 37,603 + Ac3H11_922 0.65 -0.6 37,603 + Ac3H11_922 0.65 -0.7 37,603 + Ac3H11_922 0.65 +0.0 37,603 + Ac3H11_922 0.65 +0.8 37,603 + Ac3H11_922 0.65 -0.9 37,603 + Ac3H11_922 0.65 +1.1 37,604 - Ac3H11_922 0.65 -0.4
Or see this region's nucleotide sequence