Experiment: m.b. Cisplatin 0.025 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Dshi_0447 and Dshi_0448 are separated by 316 nucleotides Dshi_0448 and Dshi_0449 are separated by 54 nucleotides Dshi_0449 and Dshi_0450 are separated by 103 nucleotides Dshi_0450 and Dshi_0451 are separated by 26 nucleotides
Dshi_0447: Dshi_0447 - transcriptional regulator, Crp/Fnr family (RefSeq), at 434,981 to 435,769
_0447
Dshi_0448: Dshi_0448 - integral membrane sensor signal transduction histidine kinase (RefSeq), at 436,086 to 437,696
_0448
Dshi_0449: Dshi_0449 - two component transcriptional regulator, winged helix family (RefSeq), at 437,751 to 438,434
_0449
Dshi_0450: Dshi_0450 - coenzyme PQQ biosynthesis protein A (RefSeq), at 438,538 to 438,636
_0450
Dshi_0451: Dshi_0451 - coenzyme PQQ biosynthesis protein B (RefSeq), at 438,663 to 439,556
_0451
Position (kb)
436
437
438 Strain fitness (log2 ratio)
-3
-2
-1
0
1
2
3 at 435.139 kb on - strand, within Dshi_0447 at 435.251 kb on + strand, within Dshi_0447 at 435.259 kb on - strand, within Dshi_0447 at 435.278 kb on + strand, within Dshi_0447 at 435.301 kb on + strand, within Dshi_0447 at 435.301 kb on + strand, within Dshi_0447 at 435.301 kb on + strand, within Dshi_0447 at 435.309 kb on - strand, within Dshi_0447 at 435.309 kb on - strand, within Dshi_0447 at 435.424 kb on + strand, within Dshi_0447 at 435.427 kb on - strand, within Dshi_0447 at 435.427 kb on - strand, within Dshi_0447 at 435.427 kb on - strand, within Dshi_0447 at 435.462 kb on + strand, within Dshi_0447 at 435.462 kb on + strand, within Dshi_0447 at 435.462 kb on + strand, within Dshi_0447 at 435.470 kb on - strand, within Dshi_0447 at 435.549 kb on + strand, within Dshi_0447 at 435.587 kb on - strand, within Dshi_0447 at 435.600 kb on + strand, within Dshi_0447 at 435.601 kb on - strand, within Dshi_0447 at 435.653 kb on - strand, within Dshi_0447 at 435.653 kb on - strand, within Dshi_0447 at 435.718 kb on - strand at 435.758 kb on - strand at 435.789 kb on + strand at 435.789 kb on + strand at 435.789 kb on + strand at 435.789 kb on + strand at 435.791 kb on + strand at 435.797 kb on - strand at 435.797 kb on - strand at 435.840 kb on + strand at 435.840 kb on + strand at 435.841 kb on + strand at 435.848 kb on - strand at 435.867 kb on - strand at 435.880 kb on + strand at 435.884 kb on - strand at 435.885 kb on + strand at 435.891 kb on + strand at 435.893 kb on - strand at 435.899 kb on - strand at 435.933 kb on + strand at 435.933 kb on + strand at 435.935 kb on + strand at 435.941 kb on - strand at 435.941 kb on - strand at 435.941 kb on - strand at 435.941 kb on - strand at 435.943 kb on - strand at 435.948 kb on + strand at 435.956 kb on - strand at 435.956 kb on - strand at 435.956 kb on - strand at 435.985 kb on + strand at 436.019 kb on + strand at 436.025 kb on - strand at 436.027 kb on - strand at 436.073 kb on + strand at 436.076 kb on - strand at 436.076 kb on - strand at 436.078 kb on + strand at 436.106 kb on + strand at 436.109 kb on + strand at 436.141 kb on + strand at 436.151 kb on + strand at 436.167 kb on + strand at 436.212 kb on - strand at 436.220 kb on + strand at 436.228 kb on - strand at 436.243 kb on + strand at 436.251 kb on - strand, within Dshi_0448 at 436.258 kb on + strand, within Dshi_0448 at 436.301 kb on + strand, within Dshi_0448 at 436.311 kb on + strand, within Dshi_0448 at 436.311 kb on + strand, within Dshi_0448 at 436.320 kb on + strand, within Dshi_0448 at 436.320 kb on + strand, within Dshi_0448 at 436.391 kb on + strand, within Dshi_0448 at 436.401 kb on + strand, within Dshi_0448 at 436.401 kb on + strand, within Dshi_0448 at 436.401 kb on + strand, within Dshi_0448 at 436.401 kb on + strand, within Dshi_0448 at 436.498 kb on + strand, within Dshi_0448 at 436.543 kb on + strand, within Dshi_0448 at 436.550 kb on + strand, within Dshi_0448 at 436.563 kb on + strand, within Dshi_0448 at 436.582 kb on + strand, within Dshi_0448 at 436.615 kb on - strand, within Dshi_0448 at 436.620 kb on - strand, within Dshi_0448 at 436.620 kb on - strand, within Dshi_0448 at 436.622 kb on + strand, within Dshi_0448 at 436.632 kb on + strand, within Dshi_0448 at 436.649 kb on + strand, within Dshi_0448 at 436.676 kb on - strand, within Dshi_0448 at 436.678 kb on + strand at 436.688 kb on + strand, within Dshi_0448 at 436.690 kb on + strand, within Dshi_0448 at 436.690 kb on + strand, within Dshi_0448 at 436.697 kb on - strand, within Dshi_0448 at 436.700 kb on + strand, within Dshi_0448 at 436.707 kb on + strand, within Dshi_0448 at 436.707 kb on + strand, within Dshi_0448 at 436.708 kb on - strand, within Dshi_0448 at 436.708 kb on - strand, within Dshi_0448 at 436.715 kb on - strand, within Dshi_0448 at 436.749 kb on + strand, within Dshi_0448 at 436.751 kb on + strand, within Dshi_0448 at 436.751 kb on + strand, within Dshi_0448 at 436.767 kb on + strand, within Dshi_0448 at 436.850 kb on + strand, within Dshi_0448 at 436.857 kb on + strand, within Dshi_0448 at 436.884 kb on + strand, within Dshi_0448 at 436.893 kb on + strand, within Dshi_0448 at 436.898 kb on + strand, within Dshi_0448 at 436.957 kb on - strand, within Dshi_0448 at 436.978 kb on + strand, within Dshi_0448 at 437.024 kb on + strand, within Dshi_0448 at 437.027 kb on - strand, within Dshi_0448 at 437.043 kb on + strand, within Dshi_0448 at 437.052 kb on + strand, within Dshi_0448 at 437.075 kb on - strand, within Dshi_0448 at 437.106 kb on - strand, within Dshi_0448 at 437.170 kb on - strand, within Dshi_0448 at 437.170 kb on - strand, within Dshi_0448 at 437.176 kb on + strand, within Dshi_0448 at 437.177 kb on + strand, within Dshi_0448 at 437.184 kb on - strand, within Dshi_0448 at 437.196 kb on + strand, within Dshi_0448 at 437.201 kb on + strand, within Dshi_0448 at 437.209 kb on - strand, within Dshi_0448 at 437.209 kb on - strand, within Dshi_0448 at 437.224 kb on - strand, within Dshi_0448 at 437.227 kb on + strand, within Dshi_0448 at 437.235 kb on - strand, within Dshi_0448 at 437.235 kb on - strand, within Dshi_0448 at 437.235 kb on - strand, within Dshi_0448 at 437.253 kb on + strand, within Dshi_0448 at 437.260 kb on - strand, within Dshi_0448 at 437.262 kb on + strand, within Dshi_0448 at 437.315 kb on + strand, within Dshi_0448 at 437.318 kb on - strand, within Dshi_0448 at 437.323 kb on - strand, within Dshi_0448 at 437.323 kb on - strand, within Dshi_0448 at 437.323 kb on - strand, within Dshi_0448 at 437.325 kb on + strand, within Dshi_0448 at 437.329 kb on - strand, within Dshi_0448 at 437.389 kb on + strand, within Dshi_0448 at 437.410 kb on + strand, within Dshi_0448 at 437.410 kb on + strand, within Dshi_0448 at 437.432 kb on + strand, within Dshi_0448 at 437.537 kb on - strand at 437.542 kb on - strand at 437.612 kb on + strand at 437.617 kb on + strand at 437.648 kb on + strand at 437.650 kb on + strand at 437.735 kb on - strand at 437.735 kb on - strand at 437.772 kb on + strand at 437.909 kb on - strand, within Dshi_0449 at 437.995 kb on - strand, within Dshi_0449 at 438.112 kb on - strand, within Dshi_0449 at 438.125 kb on + strand, within Dshi_0449 at 438.151 kb on - strand, within Dshi_0449 at 438.152 kb on - strand, within Dshi_0449 at 438.179 kb on - strand, within Dshi_0449 at 438.181 kb on + strand, within Dshi_0449 at 438.189 kb on - strand, within Dshi_0449 at 438.272 kb on + strand, within Dshi_0449 at 438.280 kb on - strand, within Dshi_0449 at 438.298 kb on - strand, within Dshi_0449 at 438.309 kb on + strand, within Dshi_0449 at 438.322 kb on - strand, within Dshi_0449 at 438.373 kb on + strand at 438.378 kb on + strand at 438.386 kb on - strand at 438.420 kb on + strand at 438.420 kb on - strand at 438.428 kb on - strand at 438.428 kb on - strand at 438.430 kb on + strand at 438.430 kb on + strand at 438.430 kb on + strand at 438.462 kb on + strand at 438.471 kb on - strand at 438.486 kb on + strand at 438.490 kb on + strand at 438.525 kb on - strand at 438.553 kb on - strand, within Dshi_0450 at 438.553 kb on - strand at 438.561 kb on - strand, within Dshi_0450 at 438.591 kb on + strand, within Dshi_0450 at 438.599 kb on + strand, within Dshi_0450 at 438.606 kb on - strand, within Dshi_0450 at 438.608 kb on + strand, within Dshi_0450 at 438.616 kb on - strand, within Dshi_0450 at 438.616 kb on - strand, within Dshi_0450 at 438.625 kb on + strand, within Dshi_0450 at 438.625 kb on + strand, within Dshi_0450 at 438.625 kb on + strand, within Dshi_0450 at 438.625 kb on + strand, within Dshi_0450 at 438.625 kb on + strand, within Dshi_0450 at 438.630 kb on + strand at 438.633 kb on - strand at 438.633 kb on - strand at 438.633 kb on - strand at 438.651 kb on + strand at 438.659 kb on - strand
Per-strain Table
Position Strand Gene LocusTag Fraction m.b. Cisplatin 0.025 mg/ml remove 435,139 - Dshi_0447 0.20 +1.0 435,251 + Dshi_0447 0.34 -0.3 435,259 - Dshi_0447 0.35 -0.9 435,278 + Dshi_0447 0.38 +0.3 435,301 + Dshi_0447 0.41 -0.7 435,301 + Dshi_0447 0.41 +0.3 435,301 + Dshi_0447 0.41 +0.1 435,309 - Dshi_0447 0.42 +0.4 435,309 - Dshi_0447 0.42 +0.4 435,424 + Dshi_0447 0.56 +0.5 435,427 - Dshi_0447 0.57 -0.1 435,427 - Dshi_0447 0.57 +1.0 435,427 - Dshi_0447 0.57 -0.7 435,462 + Dshi_0447 0.61 +0.5 435,462 + Dshi_0447 0.61 -0.8 435,462 + Dshi_0447 0.61 -1.3 435,470 - Dshi_0447 0.62 -0.3 435,549 + Dshi_0447 0.72 +0.7 435,587 - Dshi_0447 0.77 -1.7 435,600 + Dshi_0447 0.78 +0.4 435,601 - Dshi_0447 0.79 +1.9 435,653 - Dshi_0447 0.85 -1.1 435,653 - Dshi_0447 0.85 +0.2 435,718 - -0.0 435,758 - -0.2 435,789 + -0.2 435,789 + -0.5 435,789 + -0.5 435,789 + +0.4 435,791 + +0.4 435,797 - -1.3 435,797 - -0.0 435,840 + +0.2 435,840 + -0.1 435,841 + -0.6 435,848 - -2.5 435,867 - +0.1 435,880 + -0.2 435,884 - -1.8 435,885 + -1.4 435,891 + +0.7 435,893 - +1.0 435,899 - +0.1 435,933 + +1.1 435,933 + +0.2 435,935 + +0.2 435,941 - -0.7 435,941 - -0.5 435,941 - -0.9 435,941 - +0.6 435,943 - +0.6 435,948 + +0.8 435,956 - -0.5 435,956 - +2.0 435,956 - +0.8 435,985 + -0.2 436,019 + +0.0 436,025 - -1.3 436,027 - -1.5 436,073 + -0.3 436,076 - -0.8 436,076 - -0.5 436,078 + -0.7 436,106 + +0.5 436,109 + -0.9 436,141 + -0.1 436,151 + +0.2 436,167 + -0.1 436,212 - -0.5 436,220 + +0.5 436,228 - +0.1 436,243 + -0.2 436,251 - Dshi_0448 0.10 +0.4 436,258 + Dshi_0448 0.11 +0.3 436,301 + Dshi_0448 0.13 -0.2 436,311 + Dshi_0448 0.14 +0.5 436,311 + Dshi_0448 0.14 +0.3 436,320 + Dshi_0448 0.15 +0.3 436,320 + Dshi_0448 0.15 +0.7 436,391 + Dshi_0448 0.19 +0.8 436,401 + Dshi_0448 0.20 +0.1 436,401 + Dshi_0448 0.20 -0.4 436,401 + Dshi_0448 0.20 +1.7 436,401 + Dshi_0448 0.20 -0.3 436,498 + Dshi_0448 0.26 +0.4 436,543 + Dshi_0448 0.28 -0.4 436,550 + Dshi_0448 0.29 -0.2 436,563 + Dshi_0448 0.30 +0.4 436,582 + Dshi_0448 0.31 -0.2 436,615 - Dshi_0448 0.33 -0.7 436,620 - Dshi_0448 0.33 -0.5 436,620 - Dshi_0448 0.33 +0.4 436,622 + Dshi_0448 0.33 +0.1 436,632 + Dshi_0448 0.34 -0.7 436,649 + Dshi_0448 0.35 -0.9 436,676 - Dshi_0448 0.37 -0.8 436,678 + +0.1 436,688 + Dshi_0448 0.37 +0.1 436,690 + Dshi_0448 0.37 -0.9 436,690 + Dshi_0448 0.37 +0.7 436,697 - Dshi_0448 0.38 +1.4 436,700 + Dshi_0448 0.38 +0.1 436,707 + Dshi_0448 0.39 +0.3 436,707 + Dshi_0448 0.39 -0.4 436,708 - Dshi_0448 0.39 +0.2 436,708 - Dshi_0448 0.39 +0.2 436,715 - Dshi_0448 0.39 +0.3 436,749 + Dshi_0448 0.41 -0.7 436,751 + Dshi_0448 0.41 +0.1 436,751 + Dshi_0448 0.41 +0.4 436,767 + Dshi_0448 0.42 +0.2 436,850 + Dshi_0448 0.47 +0.1 436,857 + Dshi_0448 0.48 -1.1 436,884 + Dshi_0448 0.50 -0.9 436,893 + Dshi_0448 0.50 -0.9 436,898 + Dshi_0448 0.50 -0.7 436,957 - Dshi_0448 0.54 -0.6 436,978 + Dshi_0448 0.55 +2.2 437,024 + Dshi_0448 0.58 +0.6 437,027 - Dshi_0448 0.58 -0.1 437,043 + Dshi_0448 0.59 +0.1 437,052 + Dshi_0448 0.60 -1.7 437,075 - Dshi_0448 0.61 -0.2 437,106 - Dshi_0448 0.63 -0.1 437,170 - Dshi_0448 0.67 -0.3 437,170 - Dshi_0448 0.67 +0.7 437,176 + Dshi_0448 0.68 +0.7 437,177 + Dshi_0448 0.68 -0.4 437,184 - Dshi_0448 0.68 +0.4 437,196 + Dshi_0448 0.69 -0.1 437,201 + Dshi_0448 0.69 +0.1 437,209 - Dshi_0448 0.70 -0.9 437,209 - Dshi_0448 0.70 +0.6 437,224 - Dshi_0448 0.71 +0.5 437,227 + Dshi_0448 0.71 -1.9 437,235 - Dshi_0448 0.71 -0.2 437,235 - Dshi_0448 0.71 -0.2 437,235 - Dshi_0448 0.71 +0.3 437,253 + Dshi_0448 0.72 +1.4 437,260 - Dshi_0448 0.73 -0.6 437,262 + Dshi_0448 0.73 -0.0 437,315 + Dshi_0448 0.76 +1.1 437,318 - Dshi_0448 0.76 +0.3 437,323 - Dshi_0448 0.77 -0.6 437,323 - Dshi_0448 0.77 -0.1 437,323 - Dshi_0448 0.77 +0.8 437,325 + Dshi_0448 0.77 -0.8 437,329 - Dshi_0448 0.77 -1.5 437,389 + Dshi_0448 0.81 -3.0 437,410 + Dshi_0448 0.82 +0.1 437,410 + Dshi_0448 0.82 +0.4 437,432 + Dshi_0448 0.84 -0.4 437,537 - +0.5 437,542 - -0.1 437,612 + +2.5 437,617 + -0.9 437,648 + -0.4 437,650 + -0.3 437,735 - -0.5 437,735 - +0.1 437,772 + -0.9 437,909 - Dshi_0449 0.23 -0.8 437,995 - Dshi_0449 0.36 -0.1 438,112 - Dshi_0449 0.53 -0.6 438,125 + Dshi_0449 0.55 +2.1 438,151 - Dshi_0449 0.58 +0.6 438,152 - Dshi_0449 0.59 -1.5 438,179 - Dshi_0449 0.63 -0.8 438,181 + Dshi_0449 0.63 -0.2 438,189 - Dshi_0449 0.64 -0.8 438,272 + Dshi_0449 0.76 +3.2 438,280 - Dshi_0449 0.77 -0.7 438,298 - Dshi_0449 0.80 -0.7 438,309 + Dshi_0449 0.82 -0.2 438,322 - Dshi_0449 0.83 +0.3 438,373 + +0.5 438,378 + -0.2 438,386 - +0.4 438,420 + +0.1 438,420 - -0.2 438,428 - -0.0 438,428 - -0.8 438,430 + -0.2 438,430 + -0.7 438,430 + +0.4 438,462 + -0.6 438,471 - -1.8 438,486 + -0.4 438,490 + -2.4 438,525 - +0.4 438,553 - Dshi_0450 0.15 +0.1 438,553 - +0.1 438,561 - Dshi_0450 0.23 +0.4 438,591 + Dshi_0450 0.54 +1.8 438,599 + Dshi_0450 0.62 -0.0 438,606 - Dshi_0450 0.69 -0.5 438,608 + Dshi_0450 0.71 -0.1 438,616 - Dshi_0450 0.79 +0.4 438,616 - Dshi_0450 0.79 -0.0 438,625 + Dshi_0450 0.88 +0.3 438,625 + Dshi_0450 0.88 -0.6 438,625 + Dshi_0450 0.88 -0.8 438,625 + Dshi_0450 0.88 +0.5 438,625 + Dshi_0450 0.88 +1.7 438,630 + -0.3 438,633 - -0.1 438,633 - +0.4 438,633 - +0.4 438,651 + -1.2 438,659 - -0.5
Or see this region's nucleotide sequence