Experiment: D-Cycloserine 0.03125 mg/ml
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Sama_0756 and Sama_0757 are separated by 542 nucleotides Sama_0757 and metH are separated by 328 nucleotides
Sama_0756: Sama_0756 - hypothetical protein (RefSeq), at 935,916 to 936,875
_0756
Sama_0757: Sama_0757 - no description, at 937,418 to 937,861
_0757
Sama_0758: metH - B12-dependent methionine synthase (RefSeq), at 938,190 to 941,930
metH
Position (kb) 937
938 Strain fitness (log2 ratio) -3
-2
-1
0
1
2 at 936.434 kb on + strand, within Sama_0756 at 936.435 kb on - strand, within Sama_0756 at 936.435 kb on - strand, within Sama_0756 at 936.436 kb on + strand, within Sama_0756 at 936.445 kb on + strand, within Sama_0756 at 936.446 kb on - strand, within Sama_0756 at 936.460 kb on + strand, within Sama_0756 at 936.461 kb on - strand, within Sama_0756 at 936.490 kb on - strand, within Sama_0756 at 936.553 kb on + strand, within Sama_0756 at 936.553 kb on + strand, within Sama_0756 at 936.553 kb on + strand, within Sama_0756 at 936.554 kb on - strand, within Sama_0756 at 936.554 kb on - strand, within Sama_0756 at 936.554 kb on - strand, within Sama_0756 at 936.554 kb on - strand, within Sama_0756 at 936.585 kb on - strand, within Sama_0756 at 936.611 kb on + strand, within Sama_0756 at 936.612 kb on - strand, within Sama_0756 at 936.613 kb on + strand, within Sama_0756 at 936.655 kb on + strand, within Sama_0756 at 936.655 kb on + strand, within Sama_0756 at 936.655 kb on + strand, within Sama_0756 at 936.655 kb on + strand, within Sama_0756 at 936.655 kb on + strand, within Sama_0756 at 936.656 kb on - strand, within Sama_0756 at 936.656 kb on - strand, within Sama_0756 at 936.656 kb on - strand, within Sama_0756 at 936.656 kb on - strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.659 kb on + strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.660 kb on - strand, within Sama_0756 at 936.778 kb on + strand, within Sama_0756 at 936.779 kb on - strand, within Sama_0756 at 936.779 kb on - strand, within Sama_0756 at 936.804 kb on + strand at 936.805 kb on - strand at 936.805 kb on - strand at 936.827 kb on + strand at 936.827 kb on + strand at 936.827 kb on + strand at 936.828 kb on - strand at 936.828 kb on - strand at 936.828 kb on - strand at 936.837 kb on + strand at 936.837 kb on + strand at 936.838 kb on - strand at 936.838 kb on - strand at 936.855 kb on + strand at 936.875 kb on + strand at 936.875 kb on + strand at 936.875 kb on + strand at 936.875 kb on + strand at 936.875 kb on + strand at 936.875 kb on + strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.876 kb on - strand at 936.891 kb on - strand at 936.893 kb on + strand at 936.893 kb on + strand at 936.894 kb on - strand at 936.894 kb on - strand at 936.921 kb on + strand at 936.922 kb on - strand at 936.922 kb on - strand at 936.947 kb on + strand at 936.947 kb on + strand at 936.948 kb on - strand at 936.972 kb on + strand at 936.972 kb on + strand at 937.003 kb on + strand at 937.007 kb on + strand at 937.008 kb on - strand at 937.008 kb on - strand at 937.016 kb on + strand at 937.016 kb on + strand at 937.016 kb on + strand at 937.016 kb on + strand at 937.017 kb on - strand at 937.017 kb on - strand at 937.017 kb on - strand at 937.017 kb on - strand at 937.017 kb on - strand at 937.030 kb on + strand at 937.030 kb on + strand at 937.031 kb on - strand at 937.031 kb on - strand at 937.031 kb on - strand at 937.031 kb on - strand at 937.037 kb on - strand at 937.037 kb on - strand at 937.052 kb on + strand at 937.117 kb on + strand at 937.118 kb on - strand at 937.118 kb on - strand at 937.118 kb on - strand at 937.188 kb on - strand at 937.268 kb on + strand at 937.268 kb on + strand at 937.268 kb on + strand at 937.268 kb on + strand at 937.268 kb on + strand at 937.269 kb on - strand at 937.269 kb on - strand at 937.269 kb on - strand at 937.269 kb on - strand at 937.269 kb on - strand at 937.275 kb on + strand at 937.275 kb on + strand at 937.275 kb on + strand at 937.275 kb on + strand at 937.276 kb on - strand at 937.276 kb on - strand at 937.276 kb on - strand at 937.276 kb on - strand at 937.298 kb on - strand at 937.301 kb on + strand at 937.301 kb on + strand at 937.301 kb on + strand at 937.301 kb on + strand at 937.301 kb on + strand at 937.302 kb on - strand at 937.302 kb on - strand at 937.302 kb on - strand at 937.302 kb on - strand at 937.355 kb on + strand at 937.355 kb on + strand at 937.356 kb on - strand at 937.377 kb on + strand at 937.389 kb on + strand at 937.390 kb on - strand at 937.397 kb on + strand at 937.397 kb on + strand at 937.397 kb on + strand at 937.397 kb on + strand at 937.398 kb on - strand at 937.398 kb on - strand at 937.532 kb on + strand, within Sama_0757 at 937.532 kb on + strand, within Sama_0757 at 937.532 kb on + strand, within Sama_0757 at 937.532 kb on + strand, within Sama_0757 at 937.533 kb on - strand, within Sama_0757 at 937.533 kb on - strand, within Sama_0757 at 937.550 kb on + strand, within Sama_0757 at 937.646 kb on + strand, within Sama_0757 at 937.646 kb on + strand, within Sama_0757 at 937.646 kb on + strand, within Sama_0757 at 937.646 kb on + strand, within Sama_0757 at 937.647 kb on - strand, within Sama_0757 at 937.647 kb on - strand, within Sama_0757 at 937.647 kb on - strand, within Sama_0757 at 937.647 kb on - strand, within Sama_0757 at 937.742 kb on + strand, within Sama_0757 at 937.742 kb on + strand, within Sama_0757 at 937.742 kb on + strand, within Sama_0757 at 937.743 kb on - strand, within Sama_0757 at 937.743 kb on - strand, within Sama_0757 at 937.791 kb on + strand, within Sama_0757 at 937.791 kb on + strand, within Sama_0757 at 937.792 kb on - strand, within Sama_0757 at 937.792 kb on - strand, within Sama_0757 at 937.825 kb on + strand at 937.825 kb on + strand at 937.826 kb on - strand at 937.826 kb on - strand at 937.826 kb on - strand at 937.826 kb on - strand at 937.839 kb on + strand at 937.839 kb on + strand at 937.840 kb on - strand at 937.840 kb on - strand at 937.844 kb on + strand at 937.844 kb on + strand at 937.845 kb on - strand at 937.845 kb on - strand at 937.845 kb on - strand at 937.871 kb on + strand at 937.872 kb on - strand at 937.872 kb on - strand at 937.872 kb on - strand at 937.886 kb on + strand at 937.886 kb on + strand at 937.886 kb on + strand at 937.887 kb on - strand at 937.893 kb on + strand at 937.893 kb on + strand at 937.893 kb on + strand at 937.893 kb on + strand at 937.894 kb on - strand at 937.894 kb on - strand at 937.894 kb on - strand at 937.894 kb on - strand at 937.913 kb on + strand at 937.913 kb on + strand at 937.915 kb on + strand at 937.915 kb on + strand at 937.915 kb on + strand at 937.915 kb on + strand at 937.915 kb on + strand at 937.916 kb on - strand at 937.916 kb on - strand at 937.931 kb on + strand at 937.931 kb on + strand at 937.932 kb on - strand at 937.936 kb on + strand at 937.936 kb on + strand at 937.937 kb on - strand at 937.937 kb on - strand at 937.954 kb on - strand at 937.992 kb on + strand at 937.993 kb on - strand at 937.993 kb on - strand at 938.085 kb on + strand at 938.086 kb on - strand at 938.092 kb on + strand at 938.092 kb on + strand at 938.092 kb on + strand at 938.093 kb on - strand at 938.093 kb on - strand at 938.093 kb on - strand at 938.102 kb on + strand at 938.103 kb on - strand at 938.103 kb on - strand at 938.108 kb on - strand at 938.176 kb on - strand at 938.176 kb on - strand at 938.192 kb on - strand at 938.192 kb on - strand at 938.192 kb on - strand at 938.203 kb on + strand at 938.204 kb on - strand at 938.204 kb on - strand at 938.255 kb on + strand at 938.256 kb on - strand at 938.267 kb on - strand at 938.267 kb on - strand at 938.291 kb on + strand at 938.291 kb on + strand at 938.291 kb on + strand at 938.294 kb on + strand at 938.294 kb on + strand at 938.294 kb on + strand at 938.294 kb on + strand at 938.309 kb on - strand at 938.309 kb on - strand at 938.309 kb on - strand at 938.332 kb on + strand at 938.359 kb on + strand at 938.360 kb on - strand at 938.360 kb on - strand at 938.360 kb on - strand at 938.381 kb on + strand at 938.382 kb on - strand at 938.384 kb on + strand at 938.384 kb on + strand at 938.384 kb on + strand at 938.384 kb on + strand at 938.384 kb on + strand at 938.385 kb on - strand at 938.385 kb on - strand at 938.385 kb on - strand at 938.385 kb on - strand at 938.385 kb on - strand at 938.385 kb on - strand at 938.549 kb on + strand at 938.550 kb on - strand at 938.550 kb on - strand at 938.604 kb on + strand, within metH at 938.626 kb on + strand, within metH at 938.626 kb on + strand, within metH at 938.704 kb on + strand, within metH at 938.756 kb on + strand, within metH at 938.756 kb on + strand, within metH at 938.757 kb on - strand, within metH at 938.808 kb on + strand, within metH at 938.809 kb on - strand, within metH at 938.833 kb on + strand, within metH at 938.833 kb on + strand, within metH at 938.833 kb on + strand, within metH at 938.834 kb on - strand, within metH at 938.834 kb on - strand, within metH at 938.834 kb on - strand, within metH at 938.843 kb on + strand, within metH at 938.856 kb on + strand, within metH at 938.856 kb on + strand, within metH
Per-strain Table
Position Strand Gene LocusTag Fraction D-Cycloserine 0.03125 mg/ml remove 936,434 + Sama_0756 0.54 +0.3 936,435 - Sama_0756 0.54 +0.2 936,435 - Sama_0756 0.54 -0.0 936,436 + Sama_0756 0.54 -0.4 936,445 + Sama_0756 0.55 -1.1 936,446 - Sama_0756 0.55 +0.6 936,460 + Sama_0756 0.57 -1.2 936,461 - Sama_0756 0.57 +0.5 936,490 - Sama_0756 0.60 -0.1 936,553 + Sama_0756 0.66 +0.1 936,553 + Sama_0756 0.66 +0.3 936,553 + Sama_0756 0.66 -0.8 936,554 - Sama_0756 0.66 -0.8 936,554 - Sama_0756 0.66 +1.1 936,554 - Sama_0756 0.66 +0.3 936,554 - Sama_0756 0.66 -0.4 936,585 - Sama_0756 0.70 +0.9 936,611 + Sama_0756 0.72 +0.3 936,612 - Sama_0756 0.72 -1.2 936,613 + Sama_0756 0.73 -0.4 936,655 + Sama_0756 0.77 -0.5 936,655 + Sama_0756 0.77 -1.0 936,655 + Sama_0756 0.77 +0.6 936,655 + Sama_0756 0.77 +0.4 936,655 + Sama_0756 0.77 +1.3 936,656 - Sama_0756 0.77 -1.0 936,656 - Sama_0756 0.77 -1.2 936,656 - Sama_0756 0.77 +0.0 936,656 - Sama_0756 0.77 -0.2 936,659 + Sama_0756 0.77 -0.6 936,659 + Sama_0756 0.77 +0.9 936,659 + Sama_0756 0.77 +0.2 936,659 + Sama_0756 0.77 -0.3 936,659 + Sama_0756 0.77 +0.3 936,659 + Sama_0756 0.77 +0.3 936,659 + Sama_0756 0.77 -0.4 936,659 + Sama_0756 0.77 -1.2 936,659 + Sama_0756 0.77 -0.5 936,660 - Sama_0756 0.78 -0.1 936,660 - Sama_0756 0.78 +0.0 936,660 - Sama_0756 0.78 +0.1 936,660 - Sama_0756 0.78 -0.6 936,660 - Sama_0756 0.78 +1.6 936,660 - Sama_0756 0.78 +0.5 936,660 - Sama_0756 0.78 +1.4 936,660 - Sama_0756 0.78 -0.6 936,660 - Sama_0756 0.78 -0.1 936,660 - Sama_0756 0.78 +0.6 936,660 - Sama_0756 0.78 -0.4 936,660 - Sama_0756 0.78 -0.0 936,778 + Sama_0756 0.90 -0.1 936,779 - Sama_0756 0.90 +0.2 936,779 - Sama_0756 0.90 +0.9 936,804 + +0.3 936,805 - +1.3 936,805 - -0.4 936,827 + -0.8 936,827 + +1.0 936,827 + +0.9 936,828 - -0.5 936,828 - +0.7 936,828 - -0.4 936,837 + -1.5 936,837 + -1.0 936,838 - -3.4 936,838 - +0.0 936,855 + -0.7 936,875 + +0.7 936,875 + -0.8 936,875 + -0.5 936,875 + -0.4 936,875 + +0.3 936,875 + -1.8 936,876 - +0.6 936,876 - -0.4 936,876 - +0.7 936,876 - -1.2 936,876 - +0.6 936,876 - -0.7 936,876 - +0.8 936,876 - -0.5 936,876 - +0.5 936,891 - +0.0 936,893 + -0.8 936,893 + +0.5 936,894 - +1.1 936,894 - +0.4 936,921 + -0.5 936,922 - -0.2 936,922 - -0.3 936,947 + -0.2 936,947 + -0.7 936,948 - +0.6 936,972 + -0.7 936,972 + -0.5 937,003 + -0.4 937,007 + +0.2 937,008 - +0.1 937,008 - -1.2 937,016 + -0.7 937,016 + -1.7 937,016 + +0.8 937,016 + +0.8 937,017 - -0.2 937,017 - +0.0 937,017 - -0.8 937,017 - +0.6 937,017 - +0.9 937,030 + +0.9 937,030 + +1.9 937,031 - +1.0 937,031 - +0.0 937,031 - -1.2 937,031 - -1.1 937,037 - -0.4 937,037 - -0.8 937,052 + -1.0 937,117 + -0.1 937,118 - -0.9 937,118 - -0.6 937,118 - -0.5 937,188 - -0.5 937,268 + -0.5 937,268 + -0.7 937,268 + +0.0 937,268 + +0.8 937,268 + -0.9 937,269 - -0.2 937,269 - -0.8 937,269 - +0.5 937,269 - -1.7 937,269 - -0.5 937,275 + -1.2 937,275 + -0.3 937,275 + -1.7 937,275 + +0.2 937,276 - -0.8 937,276 - -0.4 937,276 - -0.7 937,276 - +0.4 937,298 - -0.4 937,301 + -0.5 937,301 + +0.5 937,301 + -0.6 937,301 + +0.8 937,301 + +1.3 937,302 - -1.2 937,302 - -1.8 937,302 - -1.8 937,302 - +0.4 937,355 + +0.1 937,355 + +0.3 937,356 - +0.4 937,377 + -0.4 937,389 + -0.6 937,390 - -0.5 937,397 + +0.6 937,397 + +0.4 937,397 + -0.2 937,397 + +0.3 937,398 - -1.3 937,398 - -0.2 937,532 + Sama_0757 0.26 -0.6 937,532 + Sama_0757 0.26 +1.3 937,532 + Sama_0757 0.26 -0.6 937,532 + Sama_0757 0.26 -0.7 937,533 - Sama_0757 0.26 +0.6 937,533 - Sama_0757 0.26 -0.3 937,550 + Sama_0757 0.30 -0.4 937,646 + Sama_0757 0.51 +0.2 937,646 + Sama_0757 0.51 -0.7 937,646 + Sama_0757 0.51 +0.0 937,646 + Sama_0757 0.51 +0.6 937,647 - Sama_0757 0.52 +0.5 937,647 - Sama_0757 0.52 +0.2 937,647 - Sama_0757 0.52 -0.4 937,647 - Sama_0757 0.52 +0.3 937,742 + Sama_0757 0.73 +0.6 937,742 + Sama_0757 0.73 -0.3 937,742 + Sama_0757 0.73 +0.0 937,743 - Sama_0757 0.73 -1.5 937,743 - Sama_0757 0.73 +0.4 937,791 + Sama_0757 0.84 -0.5 937,791 + Sama_0757 0.84 +2.2 937,792 - Sama_0757 0.84 -0.7 937,792 - Sama_0757 0.84 +0.6 937,825 + +1.0 937,825 + -2.3 937,826 - +0.2 937,826 - -0.2 937,826 - +0.8 937,826 - -0.7 937,839 + -0.2 937,839 + -0.7 937,840 - +0.5 937,840 - -0.0 937,844 + +0.6 937,844 + -1.8 937,845 - +2.0 937,845 - -0.2 937,845 - +0.4 937,871 + +0.0 937,872 - -0.4 937,872 - +1.0 937,872 - +0.0 937,886 + +0.4 937,886 + +0.2 937,886 + +1.2 937,887 - -1.4 937,893 + -1.2 937,893 + -2.3 937,893 + -0.3 937,893 + -0.2 937,894 - +0.2 937,894 - -0.7 937,894 - -0.1 937,894 - -1.0 937,913 + -0.4 937,913 + -0.2 937,915 + -0.0 937,915 + -0.7 937,915 + -1.0 937,915 + -0.6 937,915 + -0.5 937,916 - -0.4 937,916 - +0.6 937,931 + -0.3 937,931 + -1.1 937,932 - -0.4 937,936 + +0.5 937,936 + -1.4 937,937 - -0.8 937,937 - -1.2 937,954 - +0.3 937,992 + -0.7 937,993 - +0.3 937,993 - -0.7 938,085 + +0.4 938,086 - -0.4 938,092 + +2.0 938,092 + -0.3 938,092 + +0.5 938,093 - -0.1 938,093 - -0.6 938,093 - -2.4 938,102 + -0.3 938,103 - +1.3 938,103 - +0.0 938,108 - -0.1 938,176 - +0.0 938,176 - +0.0 938,192 - -1.7 938,192 - -1.0 938,192 - -0.8 938,203 + -1.2 938,204 - -1.6 938,204 - -0.2 938,255 + -0.5 938,256 - +0.5 938,267 - -1.6 938,267 - -0.6 938,291 + +0.9 938,291 + -0.1 938,291 + -0.2 938,294 + -0.5 938,294 + -0.9 938,294 + +1.6 938,294 + +1.1 938,309 - +0.3 938,309 - +1.0 938,309 - -1.1 938,332 + -0.6 938,359 + -1.0 938,360 - -1.9 938,360 - -1.7 938,360 - -1.2 938,381 + -1.3 938,382 - +0.1 938,384 + -0.6 938,384 + -2.3 938,384 + +0.7 938,384 + -0.2 938,384 + -1.1 938,385 - -0.6 938,385 - +0.4 938,385 - -0.5 938,385 - +0.9 938,385 - -0.8 938,385 - -1.0 938,549 + +0.2 938,550 - +0.1 938,550 - -1.6 938,604 + metH Sama_0758 0.11 -0.1 938,626 + metH Sama_0758 0.12 +0.0 938,626 + metH Sama_0758 0.12 -0.2 938,704 + metH Sama_0758 0.14 -1.0 938,756 + metH Sama_0758 0.15 -0.2 938,756 + metH Sama_0758 0.15 -0.3 938,757 - metH Sama_0758 0.15 +1.1 938,808 + metH Sama_0758 0.17 -1.1 938,809 - metH Sama_0758 0.17 -0.1 938,833 + metH Sama_0758 0.17 +2.0 938,833 + metH Sama_0758 0.17 +0.4 938,833 + metH Sama_0758 0.17 +0.2 938,834 - metH Sama_0758 0.17 -1.1 938,834 - metH Sama_0758 0.17 +0.1 938,834 - metH Sama_0758 0.17 -0.7 938,843 + metH Sama_0758 0.17 -1.5 938,856 + metH Sama_0758 0.18 +0.5 938,856 + metH Sama_0758 0.18 +0.0
Or see this region's nucleotide sequence