Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3762c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3761c and Rv3762c are separated by 78 nucleotidesRv3762c and Rv3763 are separated by 170 nucleotidesRv3763 and Rv3764c are separated by 55 nucleotides Rv3761c: Rv3761c - Possible acyl-CoA dehydrogenase FadE36, at 4,205,862 to 4,206,917 Rv3761c Rv3762c: Rv3762c - Possible hydrolase, at 4,206,996 to 4,208,876 Rv3762c Rv3763: Rv3763 - 19 kDa lipoprotein antigen precursor LpqH, at 4,209,047 to 4,209,526 Rv3763 Rv3764c: Rv3764c - Possible two component sensor kinase TcrY, at 4,209,582 to 4,211,009 Rv3764c Position (kb) 4206 4207 4208 4209Strain fitness (log2 ratio) -2 -1 0 1at 4206.049 kb on - strand, within Rv3761cat 4206.073 kb on + strand, within Rv3761cat 4206.074 kb on - strand, within Rv3761cat 4206.141 kb on + strand, within Rv3761cat 4206.142 kb on - strand, within Rv3761cat 4206.142 kb on - strand, within Rv3761cat 4206.165 kb on + strand, within Rv3761cat 4206.166 kb on - strand, within Rv3761cat 4206.483 kb on - strand, within Rv3761cat 4206.778 kb on + strand, within Rv3761cat 4206.929 kb on - strandat 4206.953 kb on - strandat 4207.101 kb on - strandat 4207.191 kb on + strand, within Rv3762cat 4207.192 kb on - strand, within Rv3762cat 4207.192 kb on - strand, within Rv3762cat 4207.613 kb on - strand, within Rv3762cat 4207.681 kb on + strand, within Rv3762cat 4207.681 kb on + strand, within Rv3762cat 4207.681 kb on + strand, within Rv3762cat 4207.682 kb on - strand, within Rv3762cat 4207.798 kb on + strand, within Rv3762cat 4207.838 kb on - strand, within Rv3762cat 4207.838 kb on - strand, within Rv3762cat 4207.838 kb on - strand, within Rv3762cat 4207.843 kb on + strand, within Rv3762cat 4207.843 kb on + strand, within Rv3762cat 4207.843 kb on + strand, within Rv3762cat 4207.844 kb on - strand, within Rv3762cat 4207.844 kb on - strand, within Rv3762cat 4208.027 kb on + strand, within Rv3762cat 4208.075 kb on - strand, within Rv3762cat 4208.269 kb on + strand, within Rv3762cat 4208.270 kb on - strand, within Rv3762cat 4208.270 kb on - strand, within Rv3762cat 4208.270 kb on - strand, within Rv3762cat 4208.270 kb on - strand, within Rv3762cat 4208.270 kb on - strand, within Rv3762cat 4208.270 kb on - strand, within Rv3762cat 4208.276 kb on - strand, within Rv3762cat 4208.438 kb on - strand, within Rv3762cat 4208.482 kb on + strand, within Rv3762cat 4208.483 kb on - strand, within Rv3762cat 4208.702 kb on - strandat 4208.888 kb on + strandat 4208.888 kb on + strandat 4208.889 kb on - strandat 4208.892 kb on - strandat 4208.906 kb on + strandat 4208.907 kb on - strandat 4208.963 kb on + strandat 4208.981 kb on - strandat 4208.989 kb on + strandat 4208.989 kb on + strandat 4208.989 kb on + strandat 4209.381 kb on - strand, within Rv3763at 4209.529 kb on + strandat 4209.529 kb on + strandat 4209.530 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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4,206,049 - Rv3761c 0.18 -0.3
4,206,073 + Rv3761c 0.20 +0.9
4,206,074 - Rv3761c 0.20 +0.2
4,206,141 + Rv3761c 0.26 -0.1
4,206,142 - Rv3761c 0.27 -1.8
4,206,142 - Rv3761c 0.27 +0.5
4,206,165 + Rv3761c 0.29 -0.1
4,206,166 - Rv3761c 0.29 -0.7
4,206,483 - Rv3761c 0.59 -0.1
4,206,778 + Rv3761c 0.87 -0.3
4,206,929 - +0.9
4,206,953 - -0.2
4,207,101 - +0.6
4,207,191 + Rv3762c 0.10 -0.3
4,207,192 - Rv3762c 0.10 -0.2
4,207,192 - Rv3762c 0.10 +0.9
4,207,613 - Rv3762c 0.33 -0.3
4,207,681 + Rv3762c 0.36 +0.2
4,207,681 + Rv3762c 0.36 -0.0
4,207,681 + Rv3762c 0.36 -0.6
4,207,682 - Rv3762c 0.36 -0.3
4,207,798 + Rv3762c 0.43 -1.4
4,207,838 - Rv3762c 0.45 +0.1
4,207,838 - Rv3762c 0.45 +0.9
4,207,838 - Rv3762c 0.45 -0.3
4,207,843 + Rv3762c 0.45 -0.1
4,207,843 + Rv3762c 0.45 -0.9
4,207,843 + Rv3762c 0.45 -0.8
4,207,844 - Rv3762c 0.45 -1.3
4,207,844 - Rv3762c 0.45 -0.7
4,208,027 + Rv3762c 0.55 -0.3
4,208,075 - Rv3762c 0.57 -0.3
4,208,269 + Rv3762c 0.68 -0.1
4,208,270 - Rv3762c 0.68 -1.1
4,208,270 - Rv3762c 0.68 +0.0
4,208,270 - Rv3762c 0.68 -0.3
4,208,270 - Rv3762c 0.68 -0.3
4,208,270 - Rv3762c 0.68 -0.0
4,208,270 - Rv3762c 0.68 -0.7
4,208,276 - Rv3762c 0.68 -0.9
4,208,438 - Rv3762c 0.77 -1.6
4,208,482 + Rv3762c 0.79 -0.1
4,208,483 - Rv3762c 0.79 -1.9
4,208,702 - +0.6
4,208,888 + +0.8
4,208,888 + -1.2
4,208,889 - -0.5
4,208,892 - -1.1
4,208,906 + +0.6
4,208,907 - -0.2
4,208,963 + -0.4
4,208,981 - -0.5
4,208,989 + +0.3
4,208,989 + -0.3
4,208,989 + +0.1
4,209,381 - Rv3763 0.70 -0.1
4,209,529 + +0.3
4,209,529 + -0.7
4,209,530 - -0.1

Or see this region's nucleotide sequence