Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3363c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3361c and Rv3362c are separated by 6 nucleotidesRv3362c and Rv3363c overlap by 20 nucleotidesRv3363c and Rv3364c overlap by 23 nucleotidesRv3364c and Rv3365c overlap by 4 nucleotides Rv3361c: Rv3361c - Conserved protein, at 3,773,016 to 3,773,567 Rv3361c Rv3362c: Rv3362c - Probable ATP/GTP-binding protein, at 3,773,574 to 3,774,155 Rv3362c Rv3363c: Rv3363c - Conserved hypothetical protein, at 3,774,136 to 3,774,504 Rv3363c Rv3364c: Rv3364c - Conserved protein, at 3,774,482 to 3,774,874 Rv3364c Rv3365c: Rv3365c - Conserved protein, at 3,774,871 to 3,777,501 Rv3365c Position (kb) 3774 3775Strain fitness (log2 ratio) -1 0 1at 3774.436 kb on - strand, within Rv3363cat 3774.436 kb on - strand, within Rv3363cat 3774.455 kb on + strand, within Rv3363cat 3774.456 kb on - strand, within Rv3363cat 3774.484 kb on - strandat 3774.746 kb on + strand, within Rv3364cat 3774.746 kb on + strand, within Rv3364cat 3775.088 kb on - strandat 3775.122 kb on - strandat 3775.368 kb on + strand, within Rv3365cat 3775.368 kb on + strand, within Rv3365cat 3775.368 kb on + strand, within Rv3365cat 3775.369 kb on - strand, within Rv3365c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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3,774,436 - Rv3363c 0.81 +0.4
3,774,436 - Rv3363c 0.81 +0.2
3,774,455 + Rv3363c 0.86 +0.9
3,774,456 - Rv3363c 0.87 +0.9
3,774,484 - -0.7
3,774,746 + Rv3364c 0.67 -0.5
3,774,746 + Rv3364c 0.67 -0.1
3,775,088 - -0.4
3,775,122 - -0.9
3,775,368 + Rv3365c 0.19 +0.5
3,775,368 + Rv3365c 0.19 +0.0
3,775,368 + Rv3365c 0.19 -1.1
3,775,369 - Rv3365c 0.19 -0.3

Or see this region's nucleotide sequence