Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2922c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2921c and Rv2922c are separated by 49 nucleotidesRv2922c and Rv2922A are separated by 11 nucleotidesRv2922A and Rv2923c overlap by 14 nucleotidesRv2923c and Rv2924c are separated by 101 nucleotides Rv2921c: Rv2921c - Probable cell division protein FtsY (SRP receptor) (signal recognition particle receptor), at 3,232,871 to 3,234,139 Rv2921c Rv2922c: Rv2922c - Probable chromosome partition protein Smc, at 3,234,189 to 3,237,806 Rv2922c Rv2922A: Rv2922A - Probable acylphosphatase AcyP (acylphosphate phosphohydrolase), at 3,237,818 to 3,238,099 Rv2922A Rv2923c: Rv2923c - Conserved protein, at 3,238,086 to 3,238,499 Rv2923c Rv2924c: Rv2924c - Probable formamidopyrimidine-DNA glycosylase Fpg (FAPY-DNA glycosylase), at 3,238,601 to 3,239,470 Rv2924c Position (kb) 3234 3235 3236 3237 3238Strain fitness (log2 ratio) -2 -1 0 1at 3234.191 kb on - strandat 3234.277 kb on - strandat 3234.284 kb on - strandat 3234.284 kb on - strandat 3235.017 kb on + strand, within Rv2922cat 3235.018 kb on - strand, within Rv2922cat 3235.509 kb on - strand, within Rv2922cat 3235.530 kb on + strand, within Rv2922cat 3235.574 kb on + strand, within Rv2922cat 3236.019 kb on + strand, within Rv2922cat 3236.811 kb on + strand, within Rv2922cat 3236.900 kb on + strand, within Rv2922cat 3237.561 kb on - strandat 3238.256 kb on - strand, within Rv2923cat 3238.399 kb on - strand, within Rv2923cat 3238.636 kb on - strandat 3238.655 kb on - strandat 3238.670 kb on + strandat 3238.670 kb on + strandat 3238.764 kb on + strand, within Rv2924cat 3238.765 kb on - strand, within Rv2924cat 3238.765 kb on - strand, within Rv2924c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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3,234,191 - +0.2
3,234,277 - +0.8
3,234,284 - -1.4
3,234,284 - -0.0
3,235,017 + Rv2922c 0.23 -0.7
3,235,018 - Rv2922c 0.23 -0.0
3,235,509 - Rv2922c 0.36 -0.9
3,235,530 + Rv2922c 0.37 -2.1
3,235,574 + Rv2922c 0.38 -0.8
3,236,019 + Rv2922c 0.51 -0.8
3,236,811 + Rv2922c 0.72 -0.7
3,236,900 + Rv2922c 0.75 -0.8
3,237,561 - -0.3
3,238,256 - Rv2923c 0.41 -0.1
3,238,399 - Rv2923c 0.76 +0.0
3,238,636 - -1.6
3,238,655 - -0.8
3,238,670 + -0.2
3,238,670 + +0.3
3,238,764 + Rv2924c 0.19 -0.1
3,238,765 - Rv2924c 0.19 +0.2
3,238,765 - Rv2924c 0.19 -0.1

Or see this region's nucleotide sequence