Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2657c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2655c and Rv2656c are separated by 1 nucleotidesRv2656c and Rv2657c overlap by 4 nucleotidesRv2657c and Rv2658c are separated by 16 nucleotidesRv2658c and Rv2659c are separated by 2 nucleotides Rv2655c: Rv2655c - Possible PhiRv2 prophage protein, at 2,977,231 to 2,978,658 Rv2655c Rv2656c: Rv2656c - Possible PhiRv2 prophage protein, at 2,978,660 to 2,979,052 Rv2656c Rv2657c: Rv2657c - Probable PhiRv2 prophage protein, at 2,979,049 to 2,979,309 Rv2657c Rv2658c: Rv2658c - Possible prophage protein, at 2,979,326 to 2,979,688 Rv2658c Rv2659c: Rv2659c - Probable PhiRv2 prophage integrase, at 2,979,691 to 2,980,818 Rv2659c Position (kb) 2979 2980Strain fitness (log2 ratio) -1 0 1 2at 2978.339 kb on + strand, within Rv2655cat 2978.528 kb on + strandat 2978.529 kb on - strandat 2978.533 kb on + strandat 2978.533 kb on + strandat 2978.534 kb on - strandat 2978.556 kb on + strandat 2978.682 kb on + strandat 2978.741 kb on + strand, within Rv2656cat 2978.916 kb on + strand, within Rv2656cat 2978.916 kb on + strand, within Rv2656cat 2978.916 kb on + strand, within Rv2656cat 2979.188 kb on + strand, within Rv2657cat 2979.188 kb on + strand, within Rv2657cat 2979.335 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.356 kb on + strandat 2979.374 kb on + strand, within Rv2658cat 2979.392 kb on + strand, within Rv2658cat 2979.393 kb on - strand, within Rv2658cat 2979.393 kb on - strand, within Rv2658cat 2979.498 kb on + strand, within Rv2658cat 2979.584 kb on + strand, within Rv2658cat 2979.584 kb on + strand, within Rv2658cat 2979.584 kb on + strand, within Rv2658cat 2979.585 kb on - strand, within Rv2658cat 2979.585 kb on - strand, within Rv2658cat 2979.585 kb on - strand, within Rv2658cat 2979.662 kb on - strandat 2979.662 kb on - strandat 2979.662 kb on - strandat 2979.665 kb on + strandat 2979.665 kb on + strandat 2979.665 kb on + strandat 2979.674 kb on - strandat 2979.914 kb on + strand, within Rv2659cat 2979.914 kb on + strand, within Rv2659cat 2979.926 kb on + strand, within Rv2659cat 2979.943 kb on + strand, within Rv2659cat 2979.943 kb on + strand, within Rv2659cat 2979.943 kb on + strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2979.944 kb on - strand, within Rv2659cat 2980.051 kb on - strand, within Rv2659cat 2980.171 kb on + strand, within Rv2659c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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2,978,339 + Rv2655c 0.78 -0.1
2,978,528 + -0.4
2,978,529 - +0.7
2,978,533 + +0.2
2,978,533 + +0.9
2,978,534 - +1.1
2,978,556 + -1.1
2,978,682 + +0.2
2,978,741 + Rv2656c 0.21 -0.4
2,978,916 + Rv2656c 0.65 -0.3
2,978,916 + Rv2656c 0.65 +0.1
2,978,916 + Rv2656c 0.65 +0.0
2,979,188 + Rv2657c 0.53 -1.7
2,979,188 + Rv2657c 0.53 +1.3
2,979,335 + -0.4
2,979,356 + -0.2
2,979,356 + +0.9
2,979,356 + -0.1
2,979,356 + +0.3
2,979,356 + +0.4
2,979,374 + Rv2658c 0.13 -0.3
2,979,392 + Rv2658c 0.18 +0.0
2,979,393 - Rv2658c 0.18 +0.1
2,979,393 - Rv2658c 0.18 -0.3
2,979,498 + Rv2658c 0.47 +0.2
2,979,584 + Rv2658c 0.71 -0.3
2,979,584 + Rv2658c 0.71 +0.1
2,979,584 + Rv2658c 0.71 +0.1
2,979,585 - Rv2658c 0.71 +0.1
2,979,585 - Rv2658c 0.71 -0.9
2,979,585 - Rv2658c 0.71 -0.1
2,979,662 - +0.9
2,979,662 - -0.7
2,979,662 - -0.2
2,979,665 + +0.6
2,979,665 + -0.6
2,979,665 + +1.6
2,979,674 - -0.7
2,979,914 + Rv2659c 0.20 -0.3
2,979,914 + Rv2659c 0.20 -0.6
2,979,926 + Rv2659c 0.21 +1.5
2,979,943 + Rv2659c 0.22 -1.0
2,979,943 + Rv2659c 0.22 +0.1
2,979,943 + Rv2659c 0.22 -0.3
2,979,944 - Rv2659c 0.22 +1.9
2,979,944 - Rv2659c 0.22 -1.7
2,979,944 - Rv2659c 0.22 -0.9
2,979,944 - Rv2659c 0.22 -1.1
2,979,944 - Rv2659c 0.22 -0.3
2,980,051 - Rv2659c 0.32 -1.1
2,980,171 + Rv2659c 0.43 -0.3

Or see this region's nucleotide sequence