Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2591

Experiment: 7H9 with Streptomycin 0.178 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Streptomycin 0.178 ug/mL
2,920,586	+		Rv2590	0.77	-0.3
2,920,586	+		Rv2590	0.77	-0.7
2,920,586	+		Rv2590	0.77	-0.3
2,920,586	+		Rv2590	0.77	-0.1
2,920,587	-		Rv2590	0.77	+0.2
2,920,587	-		Rv2590	0.77	-0.4
2,920,587	-		Rv2590	0.77	+1.3
2,920,592	+		Rv2590	0.78	-0.1
2,920,592	+		Rv2590	0.78	-1.5
2,920,592	+		Rv2590	0.78	+0.1
2,920,592	+		Rv2590	0.78	-0.6
2,920,592	+		Rv2590	0.78	-0.6
2,920,593	-		Rv2590	0.78	+0.0
2,920,695	-		Rv2590	0.81	-0.4
2,920,695	-		Rv2590	0.81	-0.5
2,920,706	+		Rv2590	0.81	+0.5
2,920,814	+		Rv2590	0.84	+0.8
2,920,816	+		Rv2590	0.84	-0.1
2,920,817	-		Rv2590	0.84	-1.5
2,920,898	+		Rv2590	0.86	-0.0
2,920,898	+		Rv2590	0.86	+0.1
2,920,898	+		Rv2590	0.86	+0.6
2,920,899	-		Rv2590	0.86	+0.4
2,920,937	+		Rv2590	0.87	-0.1
2,920,937	+		Rv2590	0.87	+1.0
2,920,937	+		Rv2590	0.87	-0.1
2,920,938	-		Rv2590	0.87	-1.1
2,920,993	+		Rv2590	0.89	-0.7
2,920,993	+		Rv2590	0.89	-0.1
2,920,993	+		Rv2590	0.89	-0.3
2,920,994	-		Rv2590	0.89	+0.5
2,920,994	-		Rv2590	0.89	-0.4
2,920,994	-		Rv2590	0.89	-0.3
2,920,994	-		Rv2590	0.89	-0.3
2,920,994	-		Rv2590	0.89	+0.2
2,921,015	+		Rv2590	0.90	+0.3
2,921,015	+		Rv2590	0.90	-0.3
2,921,015	+		Rv2590	0.90	-0.1
2,921,086	+				+0.3
2,921,123	+				-0.1
2,921,213	+				+0.6
2,921,214	-				-0.6
2,921,342	+				-0.4
2,921,343	-				-0.2
2,921,343	-				+1.9
2,921,343	-				-0.1
2,921,420	+				+2.0
2,921,448	+				-0.7
2,921,448	+				+0.2
2,921,690	+				-0.2
2,921,690	+				-0.8
2,921,691	-				+0.6
2,921,691	-				-0.1
2,921,700	+				+1.6
2,921,701	-				+0.0
2,921,735	-		Rv2591	0.11	+0.1
2,921,809	+		Rv2591	0.16	+1.3
2,922,389	+		Rv2591	0.51	-0.1
2,922,390	-		Rv2591	0.51	+0.5
2,922,390	-		Rv2591	0.51	-0.8
2,922,390	-		Rv2591	0.51	-2.0
2,922,631	-		Rv2591	0.66	+0.4
2,922,969	+		Rv2591	0.87	+0.2
2,922,969	+		Rv2591	0.87	-0.9
2,922,969	+		Rv2591	0.87	+0.0
2,922,969	+		Rv2591	0.87	-0.8
2,922,969	+		Rv2591	0.87	+0.2
2,922,969	+		Rv2591	0.87	+0.1
2,922,969	+		Rv2591	0.87	+0.5
2,923,200	+				+0.6