Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1911c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1909c and Rv1910c are separated by 113 nucleotidesRv1910c and Rv1911c are separated by 82 nucleotidesRv1911c and Rv1912c are separated by 99 nucleotides Rv1909c: Rv1909c - Ferric uptake regulation protein FurA (fur), at 2,156,149 to 2,156,592 Rv1909c Rv1910c: Rv1910c - Probable exported protein, at 2,156,706 to 2,157,299 Rv1910c Rv1911c: Rv1911c - Probable lipoprotein LppC, at 2,157,382 to 2,157,987 Rv1911c Rv1912c: Rv1912c - Possible oxidoreductase FadB5, at 2,158,087 to 2,159,091 Rv1912c Position (kb) 2157 2158Strain fitness (log2 ratio) -1 0 1at 2156.423 kb on + strand, within Rv1909cat 2156.440 kb on + strand, within Rv1909cat 2156.584 kb on - strandat 2156.595 kb on + strandat 2156.596 kb on - strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.602 kb on + strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.603 kb on - strandat 2156.716 kb on + strandat 2156.716 kb on + strandat 2156.716 kb on + strandat 2156.717 kb on - strandat 2156.876 kb on - strand, within Rv1910cat 2156.983 kb on + strand, within Rv1910cat 2156.983 kb on + strand, within Rv1910cat 2156.984 kb on - strand, within Rv1910cat 2157.063 kb on - strand, within Rv1910cat 2157.082 kb on + strand, within Rv1910cat 2157.082 kb on + strand, within Rv1910cat 2157.082 kb on + strand, within Rv1910cat 2157.135 kb on + strand, within Rv1910cat 2157.162 kb on - strand, within Rv1910cat 2157.162 kb on - strand, within Rv1910cat 2157.555 kb on - strand, within Rv1911cat 2157.663 kb on - strand, within Rv1911cat 2157.663 kb on - strand, within Rv1911cat 2157.878 kb on + strand, within Rv1911cat 2157.878 kb on + strand, within Rv1911cat 2157.959 kb on - strandat 2158.010 kb on + strandat 2158.010 kb on + strandat 2158.011 kb on - strandat 2158.013 kb on + strandat 2158.436 kb on + strand, within Rv1912cat 2158.436 kb on + strand, within Rv1912cat 2158.437 kb on - strand, within Rv1912cat 2158.688 kb on + strand, within Rv1912c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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2,156,423 + Rv1909c 0.62 +0.9
2,156,440 + Rv1909c 0.66 -0.1
2,156,584 - -0.2
2,156,595 + -0.5
2,156,596 - -0.3
2,156,602 + -0.6
2,156,602 + +0.9
2,156,602 + -0.9
2,156,602 + -0.6
2,156,602 + +0.5
2,156,603 - +0.3
2,156,603 - +0.1
2,156,603 - +0.4
2,156,603 - -0.4
2,156,603 - -0.8
2,156,716 + -0.3
2,156,716 + -0.1
2,156,716 + -0.1
2,156,717 - -1.2
2,156,876 - Rv1910c 0.29 +1.0
2,156,983 + Rv1910c 0.47 -0.6
2,156,983 + Rv1910c 0.47 +0.5
2,156,984 - Rv1910c 0.47 -0.1
2,157,063 - Rv1910c 0.60 -0.3
2,157,082 + Rv1910c 0.63 -0.4
2,157,082 + Rv1910c 0.63 +0.0
2,157,082 + Rv1910c 0.63 +0.9
2,157,135 + Rv1910c 0.72 -0.3
2,157,162 - Rv1910c 0.77 +0.2
2,157,162 - Rv1910c 0.77 -0.6
2,157,555 - Rv1911c 0.29 -0.3
2,157,663 - Rv1911c 0.46 +0.6
2,157,663 - Rv1911c 0.46 +0.8
2,157,878 + Rv1911c 0.82 +0.1
2,157,878 + Rv1911c 0.82 +0.8
2,157,959 - +0.9
2,158,010 + -0.4
2,158,010 + -0.3
2,158,011 - +0.9
2,158,013 + -0.3
2,158,436 + Rv1912c 0.35 -0.1
2,158,436 + Rv1912c 0.35 -0.1
2,158,437 - Rv1912c 0.35 -0.0
2,158,688 + Rv1912c 0.60 -0.5

Or see this region's nucleotide sequence