Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1448c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1447c and Rv1448c overlap by 4 nucleotidesRv1448c and Rv1449c are separated by 16 nucleotides Rv1447c: Rv1447c - Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD), at 1,625,418 to 1,626,962 Rv1447c Rv1448c: Rv1448c - Probable transaldolase Tal, at 1,626,959 to 1,628,080 Rv1448c Rv1449c: Rv1449c - Transketolase Tkt (TK), at 1,628,097 to 1,630,199 Rv1449c Position (kb) 1626 1627 1628 1629Strain fitness (log2 ratio) -1 0 1 2at 1626.542 kb on - strand, within Rv1447cat 1626.542 kb on - strand, within Rv1447cat 1626.719 kb on - strand, within Rv1447cat 1626.719 kb on - strand, within Rv1447cat 1627.002 kb on - strandat 1627.002 kb on - strandat 1627.227 kb on + strand, within Rv1448cat 1627.228 kb on - strand, within Rv1448cat 1627.357 kb on - strand, within Rv1448cat 1627.854 kb on - strand, within Rv1448cat 1627.896 kb on + strand, within Rv1448cat 1628.034 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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1,626,542 - Rv1447c 0.73 +0.9
1,626,542 - Rv1447c 0.73 -0.7
1,626,719 - Rv1447c 0.84 +0.4
1,626,719 - Rv1447c 0.84 +0.4
1,627,002 - +0.3
1,627,002 - +1.3
1,627,227 + Rv1448c 0.24 +2.3
1,627,228 - Rv1448c 0.24 +0.7
1,627,357 - Rv1448c 0.35 +0.2
1,627,854 - Rv1448c 0.80 +0.2
1,627,896 + Rv1448c 0.84 +0.4
1,628,034 - +0.3

Or see this region's nucleotide sequence