Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1146

Experiment: 7H9 with Streptomycin 0.178 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with Streptomycin 0.178 ug/mL
1,272,361	+				-0.3
1,272,362	-				+0.3
1,272,362	-				-0.8
1,272,723	+		Rv1145	0.33	-0.6
1,272,723	+		Rv1145	0.33	-0.5
1,272,724	-		Rv1145	0.33	-0.0
1,272,922	-		Rv1145	0.55	+0.2
1,273,094	+		Rv1145	0.74	+0.5
1,273,136	+		Rv1145	0.78	-0.0
1,273,136	+		Rv1145	0.78	-0.8
1,273,137	-		Rv1145	0.78	+0.1
1,273,168	-		Rv1145	0.82	-0.1
1,273,168	-		Rv1145	0.82	-0.1
1,273,326	-				-0.5
1,273,419	+				-0.4
1,273,420	-				-1.3
1,273,420	-				+0.2
1,273,675	+		Rv1146	0.23	-0.1
1,273,716	+		Rv1146	0.26	+0.9
1,273,717	-		Rv1146	0.26	-0.3
1,273,769	+		Rv1146	0.29	+0.5
1,273,769	+		Rv1146	0.29	-0.1
1,273,770	-		Rv1146	0.29	-0.2
1,273,770	-		Rv1146	0.29	+0.4
1,273,770	-		Rv1146	0.29	-0.3
1,273,800	+		Rv1146	0.31	-0.3
1,273,801	-		Rv1146	0.32	-0.7
1,274,062	-		Rv1146	0.50	-2.0
1,274,062	-		Rv1146	0.50	+0.0
1,274,068	-		Rv1146	0.50	+0.3
1,274,084	+		Rv1146	0.52	-0.1
1,274,084	+		Rv1146	0.52	-0.2
1,274,084	+		Rv1146	0.52	+0.6
1,274,084	+		Rv1146	0.52	-0.1
1,274,084	+		Rv1146	0.52	-0.2
1,274,084	+		Rv1146	0.52	+0.1
1,274,084	+		Rv1146	0.52	-1.5
1,274,085	-		Rv1146	0.52	-1.4
1,274,085	-		Rv1146	0.52	-0.1
1,274,085	-		Rv1146	0.52	-0.4
1,274,085	-		Rv1146	0.52	-0.3
1,274,085	-		Rv1146	0.52	-0.1
1,274,088	+		Rv1146	0.52	-0.7
1,274,088	+		Rv1146	0.52	-0.3
1,274,088	+		Rv1146	0.52	-0.2
1,274,088	+		Rv1146	0.52	-0.5
1,274,088	+		Rv1146	0.52	-1.0
1,274,089	-		Rv1146	0.52	-0.3
1,274,089	-		Rv1146	0.52	-0.2
1,274,144	-		Rv1146	0.56	-0.1
1,274,152	-		Rv1146	0.56	-0.7
1,274,248	+		Rv1146	0.63	-0.1
1,274,248	+		Rv1146	0.63	+0.3
1,274,249	-		Rv1146	0.63	+0.3
1,274,249	-		Rv1146	0.63	-1.1
1,274,259	+		Rv1146	0.64	+0.3
1,274,259	+		Rv1146	0.64	-0.3
1,274,295	-		Rv1146	0.67	-0.1
1,274,327	+		Rv1146	0.69	+0.3
1,274,824	+				-0.1
1,274,825	-				+0.5
1,274,994	+		Rv1147	0.14	-0.8
1,274,994	+		Rv1147	0.14	-0.2
1,274,995	-		Rv1147	0.15	-0.6
1,275,078	-		Rv1147	0.27	-0.1
1,275,080	+		Rv1147	0.28	-0.2
1,275,298	-		Rv1147	0.61	-0.9
1,275,298	-		Rv1147	0.61	+0.3
1,275,298	-		Rv1147	0.61	-0.3
1,275,300	+		Rv1147	0.61	-0.5
1,275,301	-		Rv1147	0.62	+0.6
1,275,324	-		Rv1147	0.65	-0.0
1,275,548	+				+0.7
1,275,549	-				-0.1
1,275,549	-				+0.5
1,275,552	+				+0.8
1,275,552	+				-0.0
1,275,552	+				+0.3
1,275,553	-				-0.5
1,275,553	-				+0.7
1,275,553	-				-0.8
1,275,553	-				+1.1
1,275,553	-				-0.5
1,275,553	-				-0.1
1,275,554	+				+0.2
1,275,554	+				+0.1
1,275,554	+				+1.2
1,275,554	+				-0.5
1,275,554	+				-0.1
1,275,554	+				-0.2
1,275,554	+				+1.0
1,275,554	+				-0.5
1,275,555	-				+0.9
1,275,555	-				-1.7
1,275,555	-				+0.8
1,275,555	-				+0.9
1,275,555	-				+0.8
1,275,555	-				-0.4
1,275,555	-				-0.5
1,275,555	-				+0.8
1,275,555	-				-0.1
1,275,558	+				+1.2
1,275,558	+				-1.8
1,275,558	+				-0.5
1,275,558	+				+0.5
1,275,559	-				-0.5
1,275,559	-				+0.5
1,275,577	-				+0.2
1,275,577	-				-0.0
1,275,577	-				+0.7
1,275,680	+				-1.1
1,275,680	+				+0.3
1,275,685	+				+0.1
1,275,685	+				-0.1
1,275,685	+				+0.0
1,275,685	+				+1.4
1,275,685	+				+0.1
1,275,686	-				-1.5
1,275,686	-				-0.2
1,275,686	-				-0.3