Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0751c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0749 and Rv0749A are separated by 80 nucleotidesRv0749A and Rv0750 are separated by 158 nucleotidesRv0750 and Rv0751c are separated by 68 nucleotidesRv0751c and Rv0752c are separated by 10 nucleotides Rv0749: Rv0749 - Possible toxin VapC31. Contains PIN domain., at 841,228 to 841,656 Rv0749 Rv0749A: Rv0749A - Hypothetical protein (fragment), at 841,737 to 841,874 Rv0749A Rv0750: Rv0750 - Conserved hypothetical protein, at 842,033 to 842,278 Rv0750 Rv0751c: Rv0751c - Probable 3-hydroxyisobutyrate dehydrogenase MmsB (hibadh), at 842,347 to 843,231 Rv0751c Rv0752c: Rv0752c - Probable acyl-CoA dehydrogenase FadE9, at 843,242 to 844,414 Rv0752c Position (kb) 842 843 844Strain fitness (log2 ratio) -1 0 1 2at 841.544 kb on + strand, within Rv0749at 841.568 kb on + strand, within Rv0749at 841.568 kb on + strand, within Rv0749at 841.672 kb on + strandat 841.738 kb on + strandat 841.739 kb on - strandat 841.996 kb on - strandat 842.021 kb on + strandat 842.021 kb on + strandat 842.021 kb on + strandat 842.021 kb on + strandat 842.022 kb on - strandat 842.022 kb on - strandat 842.043 kb on + strandat 842.044 kb on - strandat 842.348 kb on + strandat 842.791 kb on + strand, within Rv0751cat 843.008 kb on + strand, within Rv0751cat 843.008 kb on + strand, within Rv0751cat 843.211 kb on + strandat 843.211 kb on + strandat 843.212 kb on - strandat 843.243 kb on + strandat 843.372 kb on + strand, within Rv0752cat 843.912 kb on + strand, within Rv0752cat 843.912 kb on + strand, within Rv0752cat 843.913 kb on - strand, within Rv0752c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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841,544 + Rv0749 0.74 -0.7
841,568 + Rv0749 0.79 -0.1
841,568 + Rv0749 0.79 -0.0
841,672 + -0.2
841,738 + -1.0
841,739 - +0.9
841,996 - +0.3
842,021 + +1.9
842,021 + -0.1
842,021 + +0.4
842,021 + +1.2
842,022 - +0.6
842,022 - +0.9
842,043 + -0.7
842,044 - -0.3
842,348 + -0.2
842,791 + Rv0751c 0.50 +0.9
843,008 + Rv0751c 0.75 +0.1
843,008 + Rv0751c 0.75 +0.3
843,211 + -0.0
843,211 + +0.2
843,212 - -0.4
843,243 + -0.7
843,372 + Rv0752c 0.11 +0.2
843,912 + Rv0752c 0.57 -0.1
843,912 + Rv0752c 0.57 +1.3
843,913 - Rv0752c 0.57 +0.4

Or see this region's nucleotide sequence