Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0630c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0629c and Rv0630c overlap by 4 nucleotidesRv0630c and Rv0631c overlap by 1 nucleotides Rv0629c: Rv0629c - Probable exonuclease V (alpha chain) RecD (exodeoxyribonuclease V alpha chain) (exodeoxyribonuclease V polypeptide), at 720,005 to 721,732 Rv0629c Rv0630c: Rv0630c - Probable exonuclease V (beta chain) RecB (exodeoxyribonuclease V beta chain)(exodeoxyribonuclease V polypeptide) (chi-specific endonuclease), at 721,729 to 725,013 Rv0630c Rv0631c: Rv0631c - Probable exonuclease V (gamma chain) RecC (exodeoxyribonuclease V gamma chain)(exodeoxyribonuclease V polypeptide), at 725,013 to 728,306 Rv0631c Position (kb) 721 722 723 724 725 726Strain fitness (log2 ratio) -2 -1 0 1 2at 721.713 kb on + strandat 721.868 kb on + strandat 722.045 kb on + strandat 722.160 kb on - strand, within Rv0630cat 722.856 kb on + strand, within Rv0630cat 722.987 kb on + strand, within Rv0630cat 722.988 kb on - strand, within Rv0630cat 722.988 kb on - strand, within Rv0630cat 723.077 kb on + strand, within Rv0630cat 723.078 kb on - strand, within Rv0630cat 723.105 kb on - strand, within Rv0630cat 724.097 kb on + strand, within Rv0630cat 724.098 kb on - strand, within Rv0630cat 724.490 kb on + strand, within Rv0630cat 724.535 kb on + strand, within Rv0630cat 724.536 kb on - strand, within Rv0630cat 725.315 kb on - strandat 725.503 kb on + strand, within Rv0631cat 725.852 kb on - strand, within Rv0631c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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721,713 + +0.9
721,868 + -0.0
722,045 + +0.1
722,160 - Rv0630c 0.13 +0.3
722,856 + Rv0630c 0.34 +0.4
722,987 + Rv0630c 0.38 +0.9
722,988 - Rv0630c 0.38 -2.6
722,988 - Rv0630c 0.38 +0.4
723,077 + Rv0630c 0.41 +0.2
723,078 - Rv0630c 0.41 +0.9
723,105 - Rv0630c 0.42 -0.5
724,097 + Rv0630c 0.72 +0.0
724,098 - Rv0630c 0.72 -0.4
724,490 + Rv0630c 0.84 +2.5
724,535 + Rv0630c 0.85 -0.9
724,536 - Rv0630c 0.85 +0.6
725,315 - -0.2
725,503 + Rv0631c 0.15 -0.1
725,852 - Rv0631c 0.25 +0.7

Or see this region's nucleotide sequence