Experiment: 7H9 with Streptomycin 0.178 ug/mL
Only strains with sufficient reads to estimate fitness are shown,
but the strain fitness values are still rather noisy and may be biased towards zero.
Strains near the edge of a gene are not shown as being associated with that
gene (they are in grey).
Strains in the central 10-90% of a gene are color coded by the insertion's strand.
Usually, "+" means that the selectable marker is encoded on the forward strand,
i.e., transcribed rightward.
500 nt Rv0505c and Rv0506 are separated by 173 nucleotides Rv0506 and Rv0507 overlap by 4 nucleotides Rv0507 and Rv0508 overlap by 8 nucleotides Rv0508 and Rv0509 are separated by 49 nucleotides
Rv0505c: Rv0505c - Possible phosphoserine phosphatase SerB1 (PSP) (O-phosphoserine phosphohydrolase) (pspase), at 595,464 to 596,585
Rv0505c
Rv0506: Rv0506 - Probable conserved membrane protein MmpS2, at 596,759 to 597,202
Rv0506
Rv0507: Rv0507 - Probable conserved transmembrane transport protein MmpL2, at 597,199 to 600,105
Rv0507
Rv0508: Rv0508 - Conserved hypothetical protein, at 600,098 to 600,391
Rv0508
Rv0509: Rv0509 - Probable glutamyl-tRNA reductase HemA (GLUTR), at 600,441 to 601,847
Rv0509
Position (kb) 597
598
599
600
601 Strain fitness (log2 ratio) -2
-1
0
1
2 at 596.650 kb on - strand at 596.654 kb on + strand at 596.659 kb on - strand at 596.682 kb on + strand at 596.683 kb on - strand at 596.683 kb on - strand at 596.691 kb on + strand at 596.692 kb on - strand at 596.708 kb on + strand at 596.720 kb on + strand at 596.721 kb on - strand at 596.730 kb on + strand at 596.731 kb on - strand at 596.731 kb on - strand at 596.845 kb on + strand, within Rv0506 at 596.846 kb on - strand, within Rv0506 at 596.846 kb on - strand, within Rv0506 at 596.846 kb on - strand, within Rv0506 at 596.846 kb on - strand, within Rv0506 at 596.846 kb on - strand, within Rv0506 at 596.945 kb on + strand, within Rv0506 at 596.945 kb on + strand, within Rv0506 at 596.946 kb on - strand, within Rv0506 at 596.946 kb on - strand, within Rv0506 at 596.946 kb on - strand, within Rv0506 at 596.946 kb on - strand, within Rv0506 at 596.946 kb on - strand, within Rv0506 at 596.985 kb on - strand, within Rv0506 at 597.357 kb on - strand at 597.444 kb on - strand at 597.496 kb on + strand, within Rv0507 at 597.496 kb on + strand, within Rv0507 at 597.497 kb on - strand, within Rv0507 at 597.497 kb on - strand, within Rv0507 at 597.497 kb on - strand, within Rv0507 at 597.497 kb on - strand, within Rv0507 at 597.498 kb on + strand, within Rv0507 at 597.613 kb on + strand, within Rv0507 at 597.614 kb on - strand, within Rv0507 at 597.625 kb on + strand, within Rv0507 at 597.625 kb on + strand, within Rv0507 at 597.626 kb on - strand, within Rv0507 at 597.655 kb on + strand, within Rv0507 at 597.721 kb on + strand, within Rv0507 at 597.721 kb on + strand, within Rv0507 at 597.777 kb on + strand, within Rv0507 at 597.778 kb on - strand, within Rv0507 at 597.778 kb on - strand, within Rv0507 at 597.778 kb on - strand, within Rv0507 at 597.778 kb on - strand, within Rv0507 at 597.783 kb on + strand, within Rv0507 at 597.828 kb on - strand, within Rv0507 at 597.830 kb on - strand, within Rv0507 at 597.997 kb on + strand, within Rv0507 at 598.005 kb on - strand, within Rv0507 at 598.132 kb on + strand, within Rv0507 at 598.132 kb on + strand, within Rv0507 at 598.133 kb on - strand, within Rv0507 at 598.408 kb on + strand, within Rv0507 at 598.408 kb on + strand, within Rv0507 at 598.409 kb on - strand, within Rv0507 at 598.409 kb on - strand, within Rv0507 at 598.731 kb on - strand, within Rv0507 at 598.783 kb on + strand, within Rv0507 at 599.124 kb on + strand, within Rv0507 at 599.125 kb on - strand, within Rv0507 at 599.392 kb on - strand, within Rv0507 at 599.403 kb on - strand, within Rv0507 at 599.434 kb on + strand, within Rv0507 at 599.434 kb on + strand, within Rv0507 at 599.776 kb on - strand, within Rv0507 at 599.871 kb on + strand at 599.872 kb on - strand at 599.872 kb on - strand at 599.887 kb on - strand at 600.103 kb on + strand at 600.103 kb on + strand at 600.104 kb on - strand at 600.104 kb on - strand at 600.308 kb on + strand, within Rv0508 at 600.308 kb on + strand, within Rv0508 at 600.309 kb on - strand, within Rv0508 at 600.309 kb on - strand, within Rv0508 at 600.346 kb on - strand, within Rv0508 at 600.376 kb on + strand at 600.384 kb on + strand at 600.402 kb on + strand
Per-strain Table
Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL remove 596,650 - -0.7 596,654 + -0.9 596,659 - -0.5 596,682 + -0.7 596,683 - -0.1 596,683 - +0.1 596,691 + -1.1 596,692 - -0.0 596,708 + -1.2 596,720 + -0.4 596,721 - -0.8 596,730 + -0.7 596,731 - -0.3 596,731 - -0.5 596,845 + Rv0506 0.19 +1.1 596,846 - Rv0506 0.20 -0.2 596,846 - Rv0506 0.20 -0.8 596,846 - Rv0506 0.20 -0.3 596,846 - Rv0506 0.20 +0.1 596,846 - Rv0506 0.20 -2.6 596,945 + Rv0506 0.42 +0.6 596,945 + Rv0506 0.42 -0.2 596,946 - Rv0506 0.42 +0.3 596,946 - Rv0506 0.42 -0.1 596,946 - Rv0506 0.42 -0.1 596,946 - Rv0506 0.42 +0.1 596,946 - Rv0506 0.42 -0.1 596,985 - Rv0506 0.51 +1.2 597,357 - -0.9 597,444 - +0.2 597,496 + Rv0507 0.10 -0.1 597,496 + Rv0507 0.10 -0.3 597,497 - Rv0507 0.10 -0.1 597,497 - Rv0507 0.10 -0.2 597,497 - Rv0507 0.10 +1.9 597,497 - Rv0507 0.10 +0.1 597,498 + Rv0507 0.10 -0.4 597,613 + Rv0507 0.14 +0.9 597,614 - Rv0507 0.14 +0.1 597,625 + Rv0507 0.15 -0.1 597,625 + Rv0507 0.15 -0.7 597,626 - Rv0507 0.15 +0.7 597,655 + Rv0507 0.16 -0.3 597,721 + Rv0507 0.18 +0.7 597,721 + Rv0507 0.18 +0.9 597,777 + Rv0507 0.20 -0.4 597,778 - Rv0507 0.20 -0.2 597,778 - Rv0507 0.20 -0.1 597,778 - Rv0507 0.20 +0.1 597,778 - Rv0507 0.20 -0.3 597,783 + Rv0507 0.20 +0.0 597,828 - Rv0507 0.22 +0.2 597,830 - Rv0507 0.22 -0.1 597,997 + Rv0507 0.27 -0.1 598,005 - Rv0507 0.28 +0.1 598,132 + Rv0507 0.32 -0.9 598,132 + Rv0507 0.32 -0.3 598,133 - Rv0507 0.32 -0.3 598,408 + Rv0507 0.42 -0.0 598,408 + Rv0507 0.42 -1.3 598,409 - Rv0507 0.42 -0.2 598,409 - Rv0507 0.42 +0.5 598,731 - Rv0507 0.53 +0.9 598,783 + Rv0507 0.54 +0.3 599,124 + Rv0507 0.66 +0.5 599,125 - Rv0507 0.66 +1.1 599,392 - Rv0507 0.75 +0.5 599,403 - Rv0507 0.76 -1.3 599,434 + Rv0507 0.77 +0.0 599,434 + Rv0507 0.77 -0.5 599,776 - Rv0507 0.89 +0.1 599,871 + +0.8 599,872 - -0.0 599,872 - -1.7 599,887 - -0.2 600,103 + -0.5 600,103 + -0.4 600,104 - -0.3 600,104 - +0.4 600,308 + Rv0508 0.71 +0.3 600,308 + Rv0508 0.71 -0.4 600,309 - Rv0508 0.72 -0.3 600,309 - Rv0508 0.72 -0.4 600,346 - Rv0508 0.84 -0.4 600,376 + -1.1 600,384 + -0.3 600,402 + -0.6
Or see this region's nucleotide sequence