Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3527
Experiment: 7H9 with Streptomycin 0.178 ug/mL
Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.
Per-strain Table
Position | Strand | Gene | LocusTag | Fraction | 7H9 with Streptomycin 0.178 ug/mL |
---|---|---|---|---|---|
remove | |||||
3,962,748 | + | Rv3526 | 0.27 | +0.1 | |
3,962,749 | - | Rv3526 | 0.27 | +0.5 | |
3,962,749 | - | Rv3526 | 0.27 | +0.8 | |
3,962,749 | - | Rv3526 | 0.27 | +0.1 | |
3,962,749 | - | Rv3526 | 0.27 | +0.0 | |
3,962,973 | - | Rv3526 | 0.46 | -0.5 | |
3,962,973 | - | Rv3526 | 0.46 | +0.0 | |
3,962,973 | - | Rv3526 | 0.46 | -0.2 | |
3,962,988 | + | Rv3526 | 0.47 | -0.7 | |
3,963,012 | + | Rv3526 | 0.49 | +0.6 | |
3,963,051 | + | Rv3526 | 0.53 | +0.7 | |
3,963,099 | + | Rv3526 | 0.57 | -0.5 | |
3,963,099 | + | Rv3526 | 0.57 | +0.7 | |
3,963,184 | - | Rv3526 | 0.64 | -0.5 | |
3,963,279 | - | Rv3526 | 0.72 | -1.0 | |
3,963,418 | - | Rv3526 | 0.84 | +1.0 | |
3,963,435 | + | Rv3526 | 0.86 | +0.2 | |
3,963,807 | - | Rv3527 | 0.45 | -1.2 | |
3,964,026 | - | -0.4 | |||
3,964,152 | - | +1.4 | |||
3,964,152 | - | +0.2 | |||
3,964,152 | - | +0.2 | |||
3,964,152 | - | +2.0 | |||
3,964,152 | - | -0.9 | |||
3,964,276 | - | -0.2 | |||
3,964,793 | + | Rv3528c | 0.44 | -0.5 | |
3,964,826 | - | Rv3528c | 0.49 | +0.2 | |
3,964,829 | + | Rv3528c | 0.49 | +0.1 | |
3,964,838 | + | Rv3528c | 0.50 | -0.3 | |
3,964,839 | - | Rv3528c | 0.50 | +1.6 | |
3,964,946 | + | Rv3528c | 0.65 | +0.2 | |
3,965,014 | - | Rv3528c | 0.75 | -0.7 |
Or see this region's nucleotide sequence