Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3510c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3509c and Rv3510c overlap by 4 nucleotidesRv3510c and Rv3511 are separated by 359 nucleotides Rv3509c: Rv3509c - Probable acetohydroxyacid synthase IlvX (acetolactate synthase), at 3,936,877 to 3,938,424 Rv3509c Rv3510c: Rv3510c - Conserved protein, at 3,938,421 to 3,939,257 Rv3510c Rv3511: Rv3511 - PE-PGRS family protein PE_PGRS55, at 3,939,617 to 3,941,761 Rv3511 Position (kb) 3938 3939 3940Strain fitness (log2 ratio) -1 0 1 2 3at 3937.588 kb on - strand, within Rv3509cat 3937.748 kb on - strand, within Rv3509cat 3938.117 kb on + strand, within Rv3509cat 3938.118 kb on - strand, within Rv3509cat 3938.252 kb on + strand, within Rv3509cat 3938.253 kb on - strand, within Rv3509cat 3938.323 kb on + strandat 3938.565 kb on - strand, within Rv3510cat 3938.641 kb on + strand, within Rv3510cat 3938.641 kb on + strand, within Rv3510cat 3938.641 kb on + strand, within Rv3510cat 3938.660 kb on - strand, within Rv3510cat 3938.711 kb on - strand, within Rv3510cat 3938.770 kb on + strand, within Rv3510cat 3938.770 kb on + strand, within Rv3510cat 3938.771 kb on - strand, within Rv3510cat 3938.771 kb on - strand, within Rv3510cat 3938.872 kb on + strand, within Rv3510cat 3938.873 kb on - strand, within Rv3510cat 3938.876 kb on - strand, within Rv3510cat 3938.876 kb on - strand, within Rv3510cat 3938.905 kb on - strand, within Rv3510cat 3939.203 kb on + strandat 3939.291 kb on + strandat 3939.332 kb on + strandat 3939.332 kb on + strandat 3939.333 kb on - strandat 3939.333 kb on - strandat 3939.397 kb on - strandat 3939.397 kb on - strandat 3939.505 kb on + strandat 3939.527 kb on + strandat 3939.527 kb on + strandat 3939.528 kb on - strandat 3939.546 kb on + strandat 3939.590 kb on + strandat 3939.591 kb on - strandat 3939.669 kb on + strandat 3939.669 kb on + strandat 3939.669 kb on + strandat 3939.784 kb on + strandat 3939.785 kb on - strandat 3939.788 kb on + strandat 3939.788 kb on + strandat 3939.788 kb on + strandat 3939.788 kb on + strandat 3939.801 kb on - strandat 3939.875 kb on + strand, within Rv3511at 3939.875 kb on + strand, within Rv3511at 3939.876 kb on - strand, within Rv3511at 3939.876 kb on - strand, within Rv3511at 3939.913 kb on - strand, within Rv3511at 3940.168 kb on - strand, within Rv3511at 3940.168 kb on - strand, within Rv3511at 3940.170 kb on - strand, within Rv3511

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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3,937,588 - Rv3509c 0.46 +0.4
3,937,748 - Rv3509c 0.56 +3.0
3,938,117 + Rv3509c 0.80 +0.2
3,938,118 - Rv3509c 0.80 +0.3
3,938,252 + Rv3509c 0.89 -0.0
3,938,253 - Rv3509c 0.89 +2.0
3,938,323 + +1.0
3,938,565 - Rv3510c 0.17 +0.8
3,938,641 + Rv3510c 0.26 +0.6
3,938,641 + Rv3510c 0.26 +0.4
3,938,641 + Rv3510c 0.26 +1.0
3,938,660 - Rv3510c 0.29 +0.5
3,938,711 - Rv3510c 0.35 -0.4
3,938,770 + Rv3510c 0.42 +0.6
3,938,770 + Rv3510c 0.42 -0.1
3,938,771 - Rv3510c 0.42 +0.5
3,938,771 - Rv3510c 0.42 +0.7
3,938,872 + Rv3510c 0.54 +0.4
3,938,873 - Rv3510c 0.54 +0.2
3,938,876 - Rv3510c 0.54 +2.6
3,938,876 - Rv3510c 0.54 +0.3
3,938,905 - Rv3510c 0.58 -0.7
3,939,203 + +0.4
3,939,291 + +1.3
3,939,332 + +0.6
3,939,332 + +1.9
3,939,333 - +1.1
3,939,333 - +0.5
3,939,397 - +0.6
3,939,397 - +0.2
3,939,505 + -0.1
3,939,527 + +0.4
3,939,527 + +0.6
3,939,528 - +0.3
3,939,546 + +0.5
3,939,590 + +0.8
3,939,591 - +0.8
3,939,669 + -0.6
3,939,669 + +0.7
3,939,669 + +1.4
3,939,784 + +0.2
3,939,785 - +0.3
3,939,788 + +1.0
3,939,788 + +0.6
3,939,788 + +0.5
3,939,788 + +0.8
3,939,801 - -0.0
3,939,875 + Rv3511 0.12 +0.9
3,939,875 + Rv3511 0.12 -0.5
3,939,876 - Rv3511 0.12 +1.1
3,939,876 - Rv3511 0.12 +1.3
3,939,913 - Rv3511 0.14 +1.2
3,940,168 - Rv3511 0.26 +0.4
3,940,168 - Rv3511 0.26 -0.2
3,940,170 - Rv3511 0.26 +1.3

Or see this region's nucleotide sequence