Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3428c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3427c and Rv3428c are separated by 97 nucleotides Rv3427c: Rv3427c - Possible transposase, at 3,843,885 to 3,844,640 Rv3427c Rv3428c: Rv3428c - Possible transposase, at 3,844,738 to 3,845,970 Rv3428c Position (kb) 3844 3845 3846Strain fitness (log2 ratio) -1 0 1at 3843.804 kb on + strandat 3843.805 kb on - strandat 3843.805 kb on - strandat 3843.829 kb on + strandat 3843.830 kb on - strandat 3843.856 kb on + strandat 3843.863 kb on + strandat 3843.886 kb on + strandat 3843.887 kb on - strandat 3844.455 kb on + strand, within Rv3427cat 3844.602 kb on - strandat 3844.606 kb on - strandat 3844.635 kb on - strandat 3845.360 kb on - strand, within Rv3428cat 3845.491 kb on - strand, within Rv3428cat 3845.959 kb on + strandat 3846.149 kb on - strandat 3846.256 kb on + strandat 3846.362 kb on + strandat 3846.363 kb on - strandat 3846.387 kb on - strandat 3846.534 kb on + strandat 3846.534 kb on + strandat 3846.535 kb on - strandat 3846.535 kb on - strandat 3846.585 kb on - strandat 3846.762 kb on - strandat 3846.762 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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3,843,804 + -0.1
3,843,805 - +0.3
3,843,805 - -0.7
3,843,829 + -1.2
3,843,830 - -0.6
3,843,856 + -0.7
3,843,863 + -0.2
3,843,886 + +0.3
3,843,887 - -0.9
3,844,455 + Rv3427c 0.75 -0.3
3,844,602 - -1.2
3,844,606 - +0.3
3,844,635 - +1.1
3,845,360 - Rv3428c 0.50 +0.1
3,845,491 - Rv3428c 0.61 +0.9
3,845,959 + +0.9
3,846,149 - +0.0
3,846,256 + -0.5
3,846,362 + +0.4
3,846,363 - -0.5
3,846,387 - +0.7
3,846,534 + -0.4
3,846,534 + +0.2
3,846,535 - -0.5
3,846,535 - +0.7
3,846,585 - -0.7
3,846,762 - +0.9
3,846,762 - +1.0

Or see this region's nucleotide sequence