Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2820c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2819c and Rv2820c overlap by 4 nucleotidesRv2820c and Rv2821c overlap by 20 nucleotidesRv2821c and Rv2822c are separated by 9 nucleotides Rv2819c: Rv2819c - Hypothetical protein, at 3,126,240 to 3,127,367 Rv2819c Rv2820c: Rv2820c - Hypothetical protein, at 3,127,364 to 3,128,272 Rv2820c Rv2821c: Rv2821c - Conserved hypothetical protein, at 3,128,253 to 3,128,963 Rv2821c Rv2822c: Rv2822c - Hypothetical protein, at 3,128,973 to 3,129,347 Rv2822c Position (kb) 3127 3128 3129Strain fitness (log2 ratio) -1 0 1at 3126.471 kb on + strand, within Rv2819cat 3126.490 kb on + strand, within Rv2819cat 3126.923 kb on - strand, within Rv2819cat 3127.014 kb on - strand, within Rv2819cat 3127.103 kb on + strand, within Rv2819cat 3127.104 kb on - strand, within Rv2819cat 3127.394 kb on + strandat 3127.414 kb on - strandat 3127.414 kb on - strandat 3127.530 kb on + strand, within Rv2820cat 3127.550 kb on + strand, within Rv2820cat 3127.573 kb on - strand, within Rv2820cat 3127.617 kb on - strand, within Rv2820cat 3128.175 kb on + strand, within Rv2820cat 3128.176 kb on - strand, within Rv2820cat 3128.176 kb on - strand, within Rv2820cat 3128.197 kb on + strandat 3128.198 kb on - strandat 3128.254 kb on + strandat 3128.684 kb on - strand, within Rv2821cat 3128.744 kb on - strand, within Rv2821cat 3128.957 kb on + strandat 3128.996 kb on - strandat 3129.004 kb on + strandat 3129.004 kb on + strandat 3129.005 kb on - strandat 3129.025 kb on + strand, within Rv2822cat 3129.063 kb on + strand, within Rv2822cat 3129.081 kb on + strand, within Rv2822cat 3129.081 kb on + strand, within Rv2822cat 3129.111 kb on - strand, within Rv2822cat 3129.111 kb on - strand, within Rv2822cat 3129.137 kb on - strand, within Rv2822cat 3129.137 kb on - strand, within Rv2822cat 3129.243 kb on + strand, within Rv2822cat 3129.244 kb on - strand, within Rv2822c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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3,126,471 + Rv2819c 0.20 +0.3
3,126,490 + Rv2819c 0.22 -0.9
3,126,923 - Rv2819c 0.61 +0.2
3,127,014 - Rv2819c 0.69 -0.2
3,127,103 + Rv2819c 0.77 -0.1
3,127,104 - Rv2819c 0.77 -0.7
3,127,394 + -0.2
3,127,414 - +0.5
3,127,414 - -0.2
3,127,530 + Rv2820c 0.18 +0.2
3,127,550 + Rv2820c 0.20 +1.4
3,127,573 - Rv2820c 0.23 +0.6
3,127,617 - Rv2820c 0.28 -0.1
3,128,175 + Rv2820c 0.89 +0.5
3,128,176 - Rv2820c 0.89 +1.5
3,128,176 - Rv2820c 0.89 -0.3
3,128,197 + -0.4
3,128,198 - -0.3
3,128,254 + +1.4
3,128,684 - Rv2821c 0.61 -0.7
3,128,744 - Rv2821c 0.69 -0.3
3,128,957 + -0.1
3,128,996 - +0.1
3,129,004 + -0.2
3,129,004 + +0.0
3,129,005 - -0.6
3,129,025 + Rv2822c 0.14 -0.1
3,129,063 + Rv2822c 0.24 -1.3
3,129,081 + Rv2822c 0.29 -0.3
3,129,081 + Rv2822c 0.29 +0.3
3,129,111 - Rv2822c 0.37 +0.0
3,129,111 - Rv2822c 0.37 -0.6
3,129,137 - Rv2822c 0.44 -0.9
3,129,137 - Rv2822c 0.44 -0.5
3,129,243 + Rv2822c 0.72 +0.1
3,129,244 - Rv2822c 0.72 +0.7

Or see this region's nucleotide sequence