Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2744c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2742c and Rv2743c are separated by 71 nucleotidesRv2743c and Rv2744c are separated by 18 nucleotidesRv2744c and Rv2745c are separated by 129 nucleotidesRv2745c and Rv2746c are separated by 70 nucleotides Rv2742c: Rv2742c - Conserved hypothetical arginine rich protein, at 3,055,515 to 3,056,348 Rv2742c Rv2743c: Rv2743c - Possible conserved transmembrane alanine rich protein, at 3,056,420 to 3,057,232 Rv2743c Rv2744c: Rv2744c - Conserved 35 kDa alanine rich protein, at 3,057,251 to 3,058,063 Rv2744c Rv2745c: Rv2745c - Transcriptional regulatory protein ClgR, at 3,058,193 to 3,058,531 Rv2745c Rv2746c: Rv2746c - Probable PGP synthase PgsA3 (CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase) (phosphatidylglycerophosphate synthase), at 3,058,602 to 3,059,231 Rv2746c Position (kb) 3057 3058 3059Strain fitness (log2 ratio) -1 0 1 2at 3056.266 kb on - strandat 3056.290 kb on + strandat 3056.291 kb on - strandat 3056.291 kb on - strandat 3056.382 kb on + strandat 3056.383 kb on - strandat 3056.383 kb on - strandat 3056.385 kb on - strandat 3056.385 kb on - strandat 3056.643 kb on + strand, within Rv2743cat 3056.643 kb on + strand, within Rv2743cat 3056.644 kb on - strand, within Rv2743cat 3056.745 kb on - strand, within Rv2743cat 3056.942 kb on + strand, within Rv2743cat 3056.942 kb on + strand, within Rv2743cat 3056.942 kb on + strand, within Rv2743cat 3056.943 kb on - strand, within Rv2743cat 3056.943 kb on - strand, within Rv2743cat 3057.065 kb on + strand, within Rv2743cat 3057.252 kb on + strandat 3057.252 kb on + strandat 3057.252 kb on + strandat 3057.253 kb on - strandat 3057.253 kb on - strandat 3057.278 kb on - strandat 3057.771 kb on + strand, within Rv2744cat 3057.771 kb on + strand, within Rv2744cat 3057.772 kb on - strand, within Rv2744cat 3058.032 kb on + strandat 3058.032 kb on + strandat 3058.033 kb on - strandat 3058.033 kb on - strandat 3058.046 kb on - strandat 3058.194 kb on + strandat 3058.195 kb on - strandat 3058.361 kb on - strand, within Rv2745cat 3058.422 kb on + strand, within Rv2745cat 3058.422 kb on + strand, within Rv2745c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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3,056,266 - +0.3
3,056,290 + +0.3
3,056,291 - +0.6
3,056,291 - +0.4
3,056,382 + +0.3
3,056,383 - +0.5
3,056,383 - +0.6
3,056,385 - +1.0
3,056,385 - +1.4
3,056,643 + Rv2743c 0.27 +0.4
3,056,643 + Rv2743c 0.27 +0.3
3,056,644 - Rv2743c 0.28 +0.9
3,056,745 - Rv2743c 0.40 +0.7
3,056,942 + Rv2743c 0.64 -1.3
3,056,942 + Rv2743c 0.64 -0.1
3,056,942 + Rv2743c 0.64 +0.5
3,056,943 - Rv2743c 0.64 +0.0
3,056,943 - Rv2743c 0.64 +0.7
3,057,065 + Rv2743c 0.79 +0.8
3,057,252 + +0.0
3,057,252 + +0.6
3,057,252 + +0.5
3,057,253 - -0.3
3,057,253 - +1.2
3,057,278 - +0.5
3,057,771 + Rv2744c 0.64 +1.0
3,057,771 + Rv2744c 0.64 +0.2
3,057,772 - Rv2744c 0.64 +0.6
3,058,032 + +0.0
3,058,032 + +2.5
3,058,033 - +2.6
3,058,033 - +0.3
3,058,046 - +0.7
3,058,194 + +0.6
3,058,195 - +0.3
3,058,361 - Rv2745c 0.50 +1.0
3,058,422 + Rv2745c 0.68 +0.7
3,058,422 + Rv2745c 0.68 +0.3

Or see this region's nucleotide sequence