Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2742c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2741 and Rv2742c are separated by 23 nucleotidesRv2742c and Rv2743c are separated by 71 nucleotidesRv2743c and Rv2744c are separated by 18 nucleotides Rv2741: Rv2741 - PE-PGRS family protein PE_PGRS47, at 3,053,914 to 3,055,491 Rv2741 Rv2742c: Rv2742c - Conserved hypothetical arginine rich protein, at 3,055,515 to 3,056,348 Rv2742c Rv2743c: Rv2743c - Possible conserved transmembrane alanine rich protein, at 3,056,420 to 3,057,232 Rv2743c Rv2744c: Rv2744c - Conserved 35 kDa alanine rich protein, at 3,057,251 to 3,058,063 Rv2744c Position (kb) 3055 3056 3057Strain fitness (log2 ratio) -2 -1 0 1 2 3at 3055.022 kb on + strand, within Rv2741at 3055.022 kb on + strand, within Rv2741at 3055.023 kb on - strand, within Rv2741at 3055.023 kb on - strand, within Rv2741at 3055.023 kb on - strand, within Rv2741at 3055.024 kb on + strand, within Rv2741at 3055.024 kb on + strand, within Rv2741at 3055.143 kb on + strand, within Rv2741at 3055.148 kb on + strand, within Rv2741at 3055.148 kb on + strand, within Rv2741at 3055.148 kb on + strand, within Rv2741at 3055.149 kb on - strand, within Rv2741at 3055.149 kb on - strand, within Rv2741at 3055.149 kb on - strand, within Rv2741at 3055.149 kb on - strand, within Rv2741at 3055.149 kb on - strand, within Rv2741at 3055.192 kb on + strand, within Rv2741at 3055.193 kb on - strand, within Rv2741at 3055.320 kb on - strand, within Rv2741at 3055.320 kb on - strand, within Rv2741at 3055.336 kb on - strandat 3055.336 kb on - strandat 3055.486 kb on - strandat 3055.781 kb on + strand, within Rv2742cat 3055.919 kb on - strand, within Rv2742cat 3055.932 kb on + strand, within Rv2742cat 3055.932 kb on + strand, within Rv2742cat 3055.940 kb on + strand, within Rv2742cat 3055.941 kb on - strand, within Rv2742cat 3055.941 kb on - strand, within Rv2742cat 3056.006 kb on + strand, within Rv2742cat 3056.061 kb on + strand, within Rv2742cat 3056.061 kb on + strand, within Rv2742cat 3056.061 kb on + strand, within Rv2742cat 3056.061 kb on + strand, within Rv2742cat 3056.062 kb on - strand, within Rv2742cat 3056.062 kb on - strand, within Rv2742cat 3056.062 kb on - strand, within Rv2742cat 3056.070 kb on + strand, within Rv2742cat 3056.077 kb on - strand, within Rv2742cat 3056.266 kb on - strandat 3056.290 kb on + strandat 3056.291 kb on - strandat 3056.291 kb on - strandat 3056.382 kb on + strandat 3056.383 kb on - strandat 3056.383 kb on - strandat 3056.385 kb on - strandat 3056.385 kb on - strandat 3056.643 kb on + strand, within Rv2743cat 3056.643 kb on + strand, within Rv2743cat 3056.644 kb on - strand, within Rv2743cat 3056.745 kb on - strand, within Rv2743cat 3056.942 kb on + strand, within Rv2743cat 3056.942 kb on + strand, within Rv2743cat 3056.942 kb on + strand, within Rv2743cat 3056.943 kb on - strand, within Rv2743cat 3056.943 kb on - strand, within Rv2743cat 3057.065 kb on + strand, within Rv2743cat 3057.252 kb on + strandat 3057.252 kb on + strandat 3057.252 kb on + strandat 3057.253 kb on - strandat 3057.253 kb on - strandat 3057.278 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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3,055,022 + Rv2741 0.70 +0.2
3,055,022 + Rv2741 0.70 +1.0
3,055,023 - Rv2741 0.70 +1.0
3,055,023 - Rv2741 0.70 +1.2
3,055,023 - Rv2741 0.70 +1.3
3,055,024 + Rv2741 0.70 +0.3
3,055,024 + Rv2741 0.70 +0.7
3,055,143 + Rv2741 0.78 +0.1
3,055,148 + Rv2741 0.78 +1.2
3,055,148 + Rv2741 0.78 +1.0
3,055,148 + Rv2741 0.78 +0.3
3,055,149 - Rv2741 0.78 -0.3
3,055,149 - Rv2741 0.78 +0.8
3,055,149 - Rv2741 0.78 +0.1
3,055,149 - Rv2741 0.78 +1.7
3,055,149 - Rv2741 0.78 +0.0
3,055,192 + Rv2741 0.81 +0.6
3,055,193 - Rv2741 0.81 +0.3
3,055,320 - Rv2741 0.89 +2.3
3,055,320 - Rv2741 0.89 +2.0
3,055,336 - +0.9
3,055,336 - -0.5
3,055,486 - +3.6
3,055,781 + Rv2742c 0.32 +1.0
3,055,919 - Rv2742c 0.48 +0.7
3,055,932 + Rv2742c 0.50 +0.5
3,055,932 + Rv2742c 0.50 +0.5
3,055,940 + Rv2742c 0.51 +0.3
3,055,941 - Rv2742c 0.51 +0.0
3,055,941 - Rv2742c 0.51 +0.8
3,056,006 + Rv2742c 0.59 +2.4
3,056,061 + Rv2742c 0.65 +0.5
3,056,061 + Rv2742c 0.65 -2.1
3,056,061 + Rv2742c 0.65 +0.5
3,056,061 + Rv2742c 0.65 +0.3
3,056,062 - Rv2742c 0.66 +0.8
3,056,062 - Rv2742c 0.66 +0.8
3,056,062 - Rv2742c 0.66 +0.4
3,056,070 + Rv2742c 0.67 +0.5
3,056,077 - Rv2742c 0.67 +0.0
3,056,266 - +0.3
3,056,290 + +0.3
3,056,291 - +0.6
3,056,291 - +0.4
3,056,382 + +0.3
3,056,383 - +0.5
3,056,383 - +0.6
3,056,385 - +1.0
3,056,385 - +1.4
3,056,643 + Rv2743c 0.27 +0.4
3,056,643 + Rv2743c 0.27 +0.3
3,056,644 - Rv2743c 0.28 +0.9
3,056,745 - Rv2743c 0.40 +0.7
3,056,942 + Rv2743c 0.64 -1.3
3,056,942 + Rv2743c 0.64 -0.1
3,056,942 + Rv2743c 0.64 +0.5
3,056,943 - Rv2743c 0.64 +0.0
3,056,943 - Rv2743c 0.64 +0.7
3,057,065 + Rv2743c 0.79 +0.8
3,057,252 + +0.0
3,057,252 + +0.6
3,057,252 + +0.5
3,057,253 - -0.3
3,057,253 - +1.2
3,057,278 - +0.5

Or see this region's nucleotide sequence