Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2427A

Experiment: 7H9 with Streptomycin 0.178 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv2427c and Rv2427A are separated by 93 nucleotidesRv2427A and Rv2428 are separated by 105 nucleotidesRv2428 and Rv2429 are separated by 25 nucleotides Rv2427c: Rv2427c - Probable gamma-glutamyl phosphate reductase protein ProA (GPR) (glutamate-5-semialdehyde dehydrogenase) (glutamyl-gamma-semialdehyde dehydrogenase), at 2,724,230 to 2,725,477 Rv2427c Rv2427A: Rv2427A - 'Transcriptional regulator OxyR', pseudogene' pseudogene=unknown transl_table=11, at 2,725,571 to 2,726,087 Rv2427A Rv2428: Rv2428 - Alkyl hydroperoxide reductase C protein AhpC (alkyl hydroperoxidase C), at 2,726,193 to 2,726,780 Rv2428 Rv2429: Rv2429 - Alkyl hydroperoxide reductase D protein AhpD (alkyl hydroperoxidase D), at 2,726,806 to 2,727,339 Rv2429 Position (kb) 2725 2726 2727Strain fitness (log2 ratio) -1 0 1at 2724.587 kb on + strand, within Rv2427cat 2724.756 kb on + strand, within Rv2427cat 2724.756 kb on + strand, within Rv2427cat 2724.757 kb on - strand, within Rv2427cat 2724.963 kb on - strand, within Rv2427cat 2725.147 kb on + strand, within Rv2427cat 2725.147 kb on + strand, within Rv2427cat 2725.148 kb on - strand, within Rv2427cat 2725.150 kb on - strand, within Rv2427cat 2725.150 kb on - strand, within Rv2427cat 2725.150 kb on - strand, within Rv2427cat 2725.334 kb on + strand, within Rv2427cat 2725.562 kb on - strandat 2725.575 kb on + strandat 2725.628 kb on - strand, within Rv2427Aat 2725.655 kb on + strand, within Rv2427Aat 2725.656 kb on - strand, within Rv2427Aat 2725.845 kb on + strand, within Rv2427Aat 2726.098 kb on - strandat 2726.292 kb on + strand, within Rv2428at 2726.812 kb on - strandat 2726.957 kb on + strand, within Rv2429

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
remove
2,724,587 + Rv2427c 0.29 +0.0
2,724,756 + Rv2427c 0.42 +0.4
2,724,756 + Rv2427c 0.42 +1.3
2,724,757 - Rv2427c 0.42 -0.1
2,724,963 - Rv2427c 0.59 +0.0
2,725,147 + Rv2427c 0.73 -0.5
2,725,147 + Rv2427c 0.73 +1.3
2,725,148 - Rv2427c 0.74 -0.4
2,725,150 - Rv2427c 0.74 +0.5
2,725,150 - Rv2427c 0.74 +0.1
2,725,150 - Rv2427c 0.74 -1.3
2,725,334 + Rv2427c 0.88 +0.3
2,725,562 - -0.9
2,725,575 + -0.9
2,725,628 - Rv2427A 0.11 -0.1
2,725,655 + Rv2427A 0.16 -0.1
2,725,656 - Rv2427A 0.16 +1.1
2,725,845 + Rv2427A 0.53 +0.8
2,726,098 - +0.4
2,726,292 + Rv2428 0.17 +0.0
2,726,812 - +0.1
2,726,957 + Rv2429 0.28 +0.0

Or see this region's nucleotide sequence