Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1593c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1592c and Rv1593c are separated by 256 nucleotidesRv1593c and Rv1594 are separated by 48 nucleotides Rv1592c: Rv1592c - Conserved hypothetical protein, at 1,792,400 to 1,793,740 Rv1592c Rv1593c: Rv1593c - Conserved protein, at 1,793,997 to 1,794,707 Rv1593c Rv1594: Rv1594 - Probable quinolinate synthetase NadA, at 1,794,756 to 1,795,805 Rv1594 Position (kb) 1793 1794 1795Strain fitness (log2 ratio) -1 0 1 2at 1793.066 kb on + strand, within Rv1592cat 1793.067 kb on - strand, within Rv1592cat 1793.067 kb on - strand, within Rv1592cat 1793.067 kb on - strand, within Rv1592cat 1793.067 kb on - strand, within Rv1592cat 1793.080 kb on - strand, within Rv1592cat 1793.226 kb on + strand, within Rv1592cat 1793.227 kb on - strand, within Rv1592cat 1793.364 kb on + strand, within Rv1592cat 1793.364 kb on + strand, within Rv1592cat 1793.409 kb on + strand, within Rv1592cat 1793.410 kb on - strand, within Rv1592cat 1793.490 kb on + strand, within Rv1592cat 1793.491 kb on - strand, within Rv1592cat 1793.551 kb on + strand, within Rv1592cat 1793.625 kb on + strandat 1793.735 kb on + strandat 1793.741 kb on + strandat 1793.741 kb on + strandat 1793.903 kb on + strandat 1793.948 kb on + strandat 1794.045 kb on + strandat 1794.046 kb on - strandat 1794.067 kb on + strandat 1794.179 kb on - strand, within Rv1593cat 1794.403 kb on + strand, within Rv1593cat 1794.404 kb on - strand, within Rv1593cat 1794.404 kb on - strand, within Rv1593cat 1794.404 kb on - strand, within Rv1593cat 1794.469 kb on - strand, within Rv1593c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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1,793,066 + Rv1592c 0.50 -0.3
1,793,067 - Rv1592c 0.50 +0.6
1,793,067 - Rv1592c 0.50 -0.4
1,793,067 - Rv1592c 0.50 -1.1
1,793,067 - Rv1592c 0.50 -0.5
1,793,080 - Rv1592c 0.51 +0.6
1,793,226 + Rv1592c 0.62 -0.1
1,793,227 - Rv1592c 0.62 -0.6
1,793,364 + Rv1592c 0.72 -0.5
1,793,364 + Rv1592c 0.72 +0.2
1,793,409 + Rv1592c 0.75 +0.9
1,793,410 - Rv1592c 0.75 -1.1
1,793,490 + Rv1592c 0.81 +1.0
1,793,491 - Rv1592c 0.81 -0.9
1,793,551 + Rv1592c 0.86 -0.1
1,793,625 + -0.6
1,793,735 + -0.7
1,793,741 + +0.0
1,793,741 + +0.0
1,793,903 + -0.8
1,793,948 + +0.0
1,794,045 + -1.0
1,794,046 - -0.6
1,794,067 + -0.4
1,794,179 - Rv1593c 0.26 +0.2
1,794,403 + Rv1593c 0.57 +1.8
1,794,404 - Rv1593c 0.57 +1.1
1,794,404 - Rv1593c 0.57 +0.3
1,794,404 - Rv1593c 0.57 -0.1
1,794,469 - Rv1593c 0.66 +0.1

Or see this region's nucleotide sequence