Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1314c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1313c and Rv1314c are separated by 165 nucleotidesRv1314c and Rv1315 are separated by 68 nucleotides Rv1313c: Rv1313c - Possible transposase, at 1,468,171 to 1,469,505 Rv1313c Rv1314c: Rv1314c - Conserved protein, at 1,469,671 to 1,470,252 Rv1314c Rv1315: Rv1315 - Probable UDP-N-acetylglucosamine 1-carboxyvinyltransferase MurA, at 1,470,321 to 1,471,577 Rv1315 Position (kb) 1469 1470 1471Strain fitness (log2 ratio) -2 -1 0 1 2at 1469.685 kb on + strandat 1469.685 kb on + strandat 1469.772 kb on - strand, within Rv1314cat 1469.772 kb on - strand, within Rv1314cat 1469.772 kb on - strand, within Rv1314cat 1469.785 kb on + strand, within Rv1314cat 1469.785 kb on + strand, within Rv1314cat 1469.785 kb on + strand, within Rv1314cat 1469.786 kb on - strand, within Rv1314cat 1469.786 kb on - strand, within Rv1314cat 1469.896 kb on + strand, within Rv1314cat 1469.899 kb on + strand, within Rv1314cat 1469.934 kb on - strand, within Rv1314cat 1469.966 kb on + strand, within Rv1314cat 1469.966 kb on + strand, within Rv1314cat 1469.967 kb on - strand, within Rv1314cat 1469.967 kb on - strand, within Rv1314cat 1469.967 kb on - strand, within Rv1314cat 1470.011 kb on - strand, within Rv1314cat 1470.186 kb on + strand, within Rv1314cat 1470.227 kb on + strandat 1470.264 kb on - strandat 1470.307 kb on - strandat 1470.309 kb on + strandat 1470.310 kb on - strandat 1470.310 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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1,469,685 + +1.0
1,469,685 + -0.2
1,469,772 - Rv1314c 0.17 +0.0
1,469,772 - Rv1314c 0.17 +0.6
1,469,772 - Rv1314c 0.17 +0.4
1,469,785 + Rv1314c 0.20 +1.7
1,469,785 + Rv1314c 0.20 +0.5
1,469,785 + Rv1314c 0.20 -2.2
1,469,786 - Rv1314c 0.20 +1.0
1,469,786 - Rv1314c 0.20 -0.2
1,469,896 + Rv1314c 0.39 +0.6
1,469,899 + Rv1314c 0.39 +0.1
1,469,934 - Rv1314c 0.45 -2.2
1,469,966 + Rv1314c 0.51 +0.1
1,469,966 + Rv1314c 0.51 -0.3
1,469,967 - Rv1314c 0.51 +0.2
1,469,967 - Rv1314c 0.51 -0.0
1,469,967 - Rv1314c 0.51 +2.0
1,470,011 - Rv1314c 0.58 +2.0
1,470,186 + Rv1314c 0.88 -0.0
1,470,227 + +0.1
1,470,264 - -0.3
1,470,307 - -0.7
1,470,309 + -0.3
1,470,310 - +0.1
1,470,310 - -0.4

Or see this region's nucleotide sequence