Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1271c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1270c and Rv1271c are separated by 212 nucleotidesRv1271c and Rv1272c are separated by 107 nucleotides Rv1270c: Rv1270c - Possible lipoprotein LprA, at 1,419,014 to 1,419,748 Rv1270c Rv1271c: Rv1271c - Conserved hypothetical secreted protein, at 1,419,961 to 1,420,302 Rv1271c Rv1272c: Rv1272c - Probable drugs-transport transmembrane ATP-binding protein ABC transporter, at 1,420,410 to 1,422,305 Rv1272c Position (kb) 1419 1420 1421Strain fitness (log2 ratio) -1 0 1at 1419.003 kb on + strandat 1419.339 kb on + strand, within Rv1270cat 1419.414 kb on + strand, within Rv1270cat 1419.414 kb on + strand, within Rv1270cat 1419.414 kb on + strand, within Rv1270cat 1419.962 kb on + strandat 1419.992 kb on + strandat 1420.019 kb on + strand, within Rv1271cat 1420.032 kb on + strand, within Rv1271cat 1420.387 kb on + strandat 1420.429 kb on + strandat 1420.680 kb on - strand, within Rv1272cat 1420.794 kb on + strand, within Rv1272cat 1420.794 kb on + strand, within Rv1272cat 1420.797 kb on + strand, within Rv1272cat 1420.858 kb on + strand, within Rv1272cat 1421.089 kb on + strand, within Rv1272cat 1421.089 kb on + strand, within Rv1272cat 1421.089 kb on + strand, within Rv1272c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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1,419,003 + +1.0
1,419,339 + Rv1270c 0.44 -1.1
1,419,414 + Rv1270c 0.54 -0.4
1,419,414 + Rv1270c 0.54 +0.0
1,419,414 + Rv1270c 0.54 +1.0
1,419,962 + -0.0
1,419,992 + -0.4
1,420,019 + Rv1271c 0.17 +0.4
1,420,032 + Rv1271c 0.21 +1.0
1,420,387 + -1.3
1,420,429 + -0.2
1,420,680 - Rv1272c 0.14 -1.2
1,420,794 + Rv1272c 0.20 -0.7
1,420,794 + Rv1272c 0.20 -0.4
1,420,797 + Rv1272c 0.20 -0.1
1,420,858 + Rv1272c 0.24 -0.2
1,421,089 + Rv1272c 0.36 +0.2
1,421,089 + Rv1272c 0.36 -0.4
1,421,089 + Rv1272c 0.36 -0.6

Or see this region's nucleotide sequence