Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1070c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1069c and Rv1070c overlap by 4 nucleotidesRv1070c and Rv1071c are separated by 11 nucleotides Rv1069c: Rv1069c - Conserved protein, at 1,192,510 to 1,194,273 Rv1069c Rv1070c: Rv1070c - Probable enoyl-CoA hydratase EchA8 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,194,270 to 1,195,043 Rv1070c Rv1071c: Rv1071c - Possible enoyl-CoA hydratase EchA9 (enoyl hydrase) (unsaturated acyl-CoA hydratase) (crotonase), at 1,195,055 to 1,196,092 Rv1071c Position (kb) 1194 1195 1196Strain fitness (log2 ratio) -2 -1 0 1 2at 1193.345 kb on - strand, within Rv1069cat 1193.345 kb on - strand, within Rv1069cat 1193.345 kb on - strand, within Rv1069cat 1193.405 kb on + strand, within Rv1069cat 1193.406 kb on - strand, within Rv1069cat 1193.822 kb on + strand, within Rv1069cat 1193.823 kb on - strand, within Rv1069cat 1193.848 kb on + strand, within Rv1069cat 1193.849 kb on - strand, within Rv1069cat 1193.979 kb on - strand, within Rv1069cat 1193.979 kb on - strand, within Rv1069cat 1193.979 kb on - strand, within Rv1069cat 1193.979 kb on - strand, within Rv1069cat 1194.014 kb on + strand, within Rv1069cat 1194.317 kb on + strandat 1194.317 kb on + strandat 1194.370 kb on + strand, within Rv1070cat 1194.370 kb on + strand, within Rv1070cat 1194.371 kb on - strand, within Rv1070cat 1194.584 kb on + strand, within Rv1070cat 1194.648 kb on + strand, within Rv1070cat 1194.734 kb on - strand, within Rv1070cat 1194.995 kb on + strandat 1195.049 kb on - strandat 1195.057 kb on - strandat 1195.225 kb on - strand, within Rv1071cat 1195.225 kb on - strand, within Rv1071cat 1195.225 kb on - strand, within Rv1071cat 1195.248 kb on - strand, within Rv1071cat 1195.337 kb on + strand, within Rv1071cat 1195.639 kb on - strand, within Rv1071cat 1195.639 kb on - strand, within Rv1071cat 1195.699 kb on + strand, within Rv1071cat 1195.699 kb on + strand, within Rv1071cat 1195.754 kb on + strand, within Rv1071cat 1195.755 kb on - strand, within Rv1071cat 1195.779 kb on + strand, within Rv1071cat 1195.818 kb on + strand, within Rv1071cat 1195.872 kb on + strand, within Rv1071c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
remove
1,193,345 - Rv1069c 0.47 +1.8
1,193,345 - Rv1069c 0.47 -0.9
1,193,345 - Rv1069c 0.47 -0.6
1,193,405 + Rv1069c 0.51 +0.6
1,193,406 - Rv1069c 0.51 +1.0
1,193,822 + Rv1069c 0.74 -0.5
1,193,823 - Rv1069c 0.74 -0.4
1,193,848 + Rv1069c 0.76 -0.3
1,193,849 - Rv1069c 0.76 -0.2
1,193,979 - Rv1069c 0.83 -0.3
1,193,979 - Rv1069c 0.83 +0.2
1,193,979 - Rv1069c 0.83 -0.1
1,193,979 - Rv1069c 0.83 -1.2
1,194,014 + Rv1069c 0.85 +0.2
1,194,317 + -0.4
1,194,317 + -0.2
1,194,370 + Rv1070c 0.13 -0.3
1,194,370 + Rv1070c 0.13 -0.7
1,194,371 - Rv1070c 0.13 -0.6
1,194,584 + Rv1070c 0.41 -0.7
1,194,648 + Rv1070c 0.49 -0.5
1,194,734 - Rv1070c 0.60 -0.3
1,194,995 + -0.4
1,195,049 - +0.2
1,195,057 - +0.2
1,195,225 - Rv1071c 0.16 -0.1
1,195,225 - Rv1071c 0.16 +0.6
1,195,225 - Rv1071c 0.16 +1.0
1,195,248 - Rv1071c 0.19 +2.0
1,195,337 + Rv1071c 0.27 +0.2
1,195,639 - Rv1071c 0.56 -1.3
1,195,639 - Rv1071c 0.56 +0.3
1,195,699 + Rv1071c 0.62 -0.6
1,195,699 + Rv1071c 0.62 -2.5
1,195,754 + Rv1071c 0.67 +0.2
1,195,755 - Rv1071c 0.67 +0.1
1,195,779 + Rv1071c 0.70 +1.0
1,195,818 + Rv1071c 0.74 +0.2
1,195,872 + Rv1071c 0.79 -1.0

Or see this region's nucleotide sequence