Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0273c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0272c and Rv0273c overlap by 4 nucleotidesRv0273c and Rv0274 are separated by 96 nucleotidesRv0274 and Rv0275c overlap by 71 nucleotides Rv0272c: Rv0272c - Unknown protein, at 328,575 to 329,708 Rv0272c Rv0273c: Rv0273c - Possible transcriptional regulatory protein, at 329,705 to 330,325 Rv0273c Rv0274: Rv0274 - Conserved protein, at 330,422 to 331,003 Rv0274 Rv0275c: Rv0275c - Possible transcriptional regulatory protein (possibly TetR-family), at 330,933 to 331,658 Rv0275c Position (kb) 329 330 331Strain fitness (log2 ratio) -1 0 1 2 3at 328.970 kb on + strand, within Rv0272cat 329.239 kb on + strand, within Rv0272cat 329.240 kb on - strand, within Rv0272cat 329.285 kb on + strand, within Rv0272cat 329.515 kb on + strand, within Rv0272cat 329.551 kb on + strand, within Rv0272cat 329.602 kb on + strandat 329.602 kb on + strandat 329.603 kb on - strandat 329.731 kb on - strandat 329.807 kb on - strand, within Rv0273cat 330.036 kb on + strand, within Rv0273cat 330.175 kb on - strand, within Rv0273cat 330.180 kb on + strand, within Rv0273cat 330.180 kb on + strand, within Rv0273cat 330.860 kb on + strand, within Rv0274at 330.860 kb on + strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.861 kb on - strand, within Rv0274at 330.865 kb on - strand, within Rv0274at 331.080 kb on + strand, within Rv0275cat 331.081 kb on - strand, within Rv0275c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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328,970 + Rv0272c 0.35 -0.5
329,239 + Rv0272c 0.59 +0.3
329,240 - Rv0272c 0.59 -0.3
329,285 + Rv0272c 0.63 +0.6
329,515 + Rv0272c 0.83 +1.6
329,551 + Rv0272c 0.86 -0.0
329,602 + +0.1
329,602 + -0.1
329,603 - -0.4
329,731 - +3.0
329,807 - Rv0273c 0.16 -1.0
330,036 + Rv0273c 0.53 +0.5
330,175 - Rv0273c 0.76 +0.2
330,180 + Rv0273c 0.76 +1.1
330,180 + Rv0273c 0.76 -0.9
330,860 + Rv0274 0.75 +0.0
330,860 + Rv0274 0.75 +1.0
330,861 - Rv0274 0.75 +0.7
330,861 - Rv0274 0.75 -1.2
330,861 - Rv0274 0.75 +0.4
330,861 - Rv0274 0.75 +0.4
330,865 - Rv0274 0.76 +2.0
331,080 + Rv0275c 0.20 -1.3
331,081 - Rv0275c 0.20 +0.4

Or see this region's nucleotide sequence