Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0243

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0242c and Rv0243 are separated by 141 nucleotidesRv0243 and Rv0244c are separated by 304 nucleotides Rv0242c: Rv0242c - Probable 3-oxoacyl-[acyl-carrier protein] reductase FabG4 (3-ketoacyl-acyl carrier protein reductase), at 290,665 to 292,029 Rv0242c Rv0243: Rv0243 - Probable acetyl-CoA acyltransferase FadA2 (3-ketoacyl-CoA thiolase) (beta-ketothiolase), at 292,171 to 293,493 Rv0243 Rv0244c: Rv0244c - Probable acyl-CoA dehydrogenase FadE5, at 293,798 to 295,633 Rv0244c Position (kb) 292 293 294Strain fitness (log2 ratio) -2 -1 0 1 2at 291.467 kb on + strand, within Rv0242cat 291.546 kb on - strand, within Rv0242cat 291.546 kb on - strand, within Rv0242cat 291.546 kb on - strand, within Rv0242cat 291.712 kb on - strand, within Rv0242cat 291.828 kb on - strand, within Rv0242cat 292.071 kb on + strandat 292.072 kb on - strandat 292.077 kb on + strandat 292.077 kb on + strandat 292.078 kb on - strandat 292.078 kb on - strandat 292.078 kb on - strandat 292.093 kb on + strandat 292.094 kb on - strandat 292.099 kb on - strandat 292.121 kb on + strandat 292.121 kb on + strandat 292.122 kb on - strandat 292.124 kb on + strandat 292.124 kb on + strandat 292.125 kb on - strandat 292.220 kb on + strandat 292.398 kb on - strand, within Rv0243at 292.398 kb on - strand, within Rv0243at 292.435 kb on + strand, within Rv0243at 292.804 kb on - strand, within Rv0243at 293.053 kb on + strand, within Rv0243at 293.053 kb on + strand, within Rv0243at 293.053 kb on + strand, within Rv0243at 293.054 kb on - strand, within Rv0243at 293.086 kb on + strand, within Rv0243at 293.087 kb on - strand, within Rv0243at 293.182 kb on + strand, within Rv0243at 293.182 kb on + strand, within Rv0243at 293.182 kb on + strand, within Rv0243at 293.248 kb on + strand, within Rv0243at 293.508 kb on + strandat 293.508 kb on + strandat 293.793 kb on - strandat 293.793 kb on - strandat 293.793 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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291,467 + Rv0242c 0.59 +1.0
291,546 - Rv0242c 0.65 -2.3
291,546 - Rv0242c 0.65 -0.3
291,546 - Rv0242c 0.65 -0.9
291,712 - Rv0242c 0.77 -1.3
291,828 - Rv0242c 0.85 +0.0
292,071 + -0.6
292,072 - +0.0
292,077 + -0.4
292,077 + -1.0
292,078 - -0.5
292,078 - -1.0
292,078 - -0.1
292,093 + -0.9
292,094 - +0.4
292,099 - +0.4
292,121 + +0.1
292,121 + +0.0
292,122 - -0.2
292,124 + -1.0
292,124 + -0.4
292,125 - +0.5
292,220 + +0.3
292,398 - Rv0243 0.17 -1.0
292,398 - Rv0243 0.17 -1.0
292,435 + Rv0243 0.20 -1.2
292,804 - Rv0243 0.48 +2.0
293,053 + Rv0243 0.67 -0.9
293,053 + Rv0243 0.67 -0.6
293,053 + Rv0243 0.67 -1.5
293,054 - Rv0243 0.67 -0.8
293,086 + Rv0243 0.69 -0.6
293,087 - Rv0243 0.69 -1.1
293,182 + Rv0243 0.76 -0.6
293,182 + Rv0243 0.76 -1.2
293,182 + Rv0243 0.76 -0.6
293,248 + Rv0243 0.81 -1.3
293,508 + +0.5
293,508 + +0.1
293,793 - -0.5
293,793 - +1.3
293,793 - -0.5

Or see this region's nucleotide sequence