Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0118c

Experiment: 7H9 with Streptomycin 0.178 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0117 and Rv0118c overlap by 17 nucleotidesRv0118c and Rv0119 are separated by 172 nucleotides Rv0117: Rv0117 - Oxidative stress response regulatory protein OxyS, at 141,200 to 142,144 Rv0117 Rv0118c: Rv0118c - Probable oxalyl-CoA decarboxylase OxcA, at 142,128 to 143,876 Rv0118c Rv0119: Rv0119 - Probable fatty-acid-CoA ligase FadD7 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 144,049 to 145,626 Rv0119 Position (kb) 142 143 144Strain fitness (log2 ratio) -1 0 1at 141.160 kb on + strandat 141.222 kb on - strandat 141.275 kb on + strandat 141.370 kb on + strand, within Rv0117at 141.397 kb on - strand, within Rv0117at 141.411 kb on + strand, within Rv0117at 141.684 kb on - strand, within Rv0117at 141.696 kb on - strand, within Rv0117at 141.769 kb on - strand, within Rv0117at 141.936 kb on + strand, within Rv0117at 142.027 kb on + strand, within Rv0117at 142.071 kb on + strandat 142.072 kb on - strandat 143.010 kb on + strand, within Rv0118cat 143.367 kb on - strand, within Rv0118cat 143.376 kb on + strand, within Rv0118cat 143.377 kb on - strand, within Rv0118cat 143.458 kb on + strand, within Rv0118cat 143.925 kb on + strandat 143.925 kb on + strandat 143.926 kb on - strandat 143.968 kb on - strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with Streptomycin 0.178 ug/mL
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141,160 + -0.0
141,222 - -0.2
141,275 + -0.5
141,370 + Rv0117 0.18 +0.2
141,397 - Rv0117 0.21 +1.6
141,411 + Rv0117 0.22 +1.0
141,684 - Rv0117 0.51 -0.2
141,696 - Rv0117 0.52 +0.3
141,769 - Rv0117 0.60 +0.1
141,936 + Rv0117 0.78 +0.7
142,027 + Rv0117 0.88 -0.4
142,071 + -0.1
142,072 - -0.8
143,010 + Rv0118c 0.50 +0.7
143,367 - Rv0118c 0.71 +0.6
143,376 + Rv0118c 0.71 +0.3
143,377 - Rv0118c 0.71 +0.2
143,458 + Rv0118c 0.76 +0.1
143,925 + -0.7
143,925 + -0.2
143,926 - -0.2
143,968 - -0.4

Or see this region's nucleotide sequence