Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3481c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3480c and Rv3481c are separated by 90 nucleotidesRv3481c and Rv3482c are separated by 141 nucleotidesRv3482c and Rv3483c are separated by 43 nucleotides Rv3480c: Rv3480c - Possible triacylglycerol synthase (diacylglycerol acyltransferase), at 3,898,909 to 3,900,402 Rv3480c Rv3481c: Rv3481c - Probable integral membrane protein, at 3,900,493 to 3,901,182 Rv3481c Rv3482c: Rv3482c - Probable conserved membrane protein, at 3,901,324 to 3,902,106 Rv3482c Rv3483c: Rv3483c - Possible exported protein, at 3,902,150 to 3,902,812 Rv3483c Position (kb) 3900 3901 3902Strain fitness (log2 ratio) -2 -1 0 1 2at 3899.617 kb on + strand, within Rv3480cat 3899.618 kb on - strand, within Rv3480cat 3899.741 kb on - strand, within Rv3480cat 3899.824 kb on + strand, within Rv3480cat 3899.824 kb on + strand, within Rv3480cat 3899.991 kb on - strand, within Rv3480cat 3900.143 kb on + strand, within Rv3480cat 3900.143 kb on + strand, within Rv3480cat 3900.191 kb on + strand, within Rv3480cat 3900.194 kb on - strand, within Rv3480cat 3900.453 kb on - strandat 3900.457 kb on - strandat 3900.457 kb on - strandat 3900.461 kb on + strandat 3900.462 kb on - strandat 3900.516 kb on - strandat 3900.526 kb on + strandat 3900.588 kb on + strand, within Rv3481cat 3901.066 kb on + strand, within Rv3481cat 3901.259 kb on + strandat 3901.290 kb on + strandat 3901.291 kb on - strandat 3901.485 kb on + strand, within Rv3482cat 3901.637 kb on + strand, within Rv3482cat 3901.637 kb on + strand, within Rv3482cat 3901.637 kb on + strand, within Rv3482cat 3901.637 kb on + strand, within Rv3482cat 3901.638 kb on - strand, within Rv3482cat 3901.649 kb on + strand, within Rv3482cat 3901.650 kb on - strand, within Rv3482cat 3901.715 kb on - strand, within Rv3482cat 3901.715 kb on - strand, within Rv3482cat 3901.862 kb on + strand, within Rv3482cat 3901.863 kb on - strand, within Rv3482cat 3901.876 kb on + strand, within Rv3482cat 3901.876 kb on + strand, within Rv3482cat 3901.876 kb on + strand, within Rv3482cat 3901.877 kb on - strand, within Rv3482cat 3901.877 kb on - strand, within Rv3482cat 3901.877 kb on - strand, within Rv3482cat 3901.877 kb on - strand, within Rv3482cat 3902.033 kb on + strandat 3902.034 kb on - strandat 3902.064 kb on + strandat 3902.066 kb on + strandat 3902.066 kb on + strandat 3902.066 kb on + strandat 3902.066 kb on + strandat 3902.067 kb on - strandat 3902.067 kb on - strandat 3902.118 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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3,899,617 + Rv3480c 0.47 +0.4
3,899,618 - Rv3480c 0.47 -1.5
3,899,741 - Rv3480c 0.56 +0.2
3,899,824 + Rv3480c 0.61 -0.4
3,899,824 + Rv3480c 0.61 -0.3
3,899,991 - Rv3480c 0.72 -1.3
3,900,143 + Rv3480c 0.83 -1.1
3,900,143 + Rv3480c 0.83 -0.8
3,900,191 + Rv3480c 0.86 +0.3
3,900,194 - Rv3480c 0.86 -0.5
3,900,453 - -0.2
3,900,457 - +1.2
3,900,457 - +0.5
3,900,461 + +0.1
3,900,462 - -0.0
3,900,516 - -1.6
3,900,526 + -0.3
3,900,588 + Rv3481c 0.14 +1.7
3,901,066 + Rv3481c 0.83 -0.4
3,901,259 + +0.4
3,901,290 + -0.5
3,901,291 - +0.7
3,901,485 + Rv3482c 0.21 -0.5
3,901,637 + Rv3482c 0.40 +0.7
3,901,637 + Rv3482c 0.40 -0.5
3,901,637 + Rv3482c 0.40 +0.5
3,901,637 + Rv3482c 0.40 +0.1
3,901,638 - Rv3482c 0.40 -0.2
3,901,649 + Rv3482c 0.42 -2.2
3,901,650 - Rv3482c 0.42 -0.1
3,901,715 - Rv3482c 0.50 +0.7
3,901,715 - Rv3482c 0.50 -0.4
3,901,862 + Rv3482c 0.69 +1.3
3,901,863 - Rv3482c 0.69 -0.1
3,901,876 + Rv3482c 0.70 -0.6
3,901,876 + Rv3482c 0.70 +2.3
3,901,876 + Rv3482c 0.70 -0.1
3,901,877 - Rv3482c 0.71 +0.9
3,901,877 - Rv3482c 0.71 -0.3
3,901,877 - Rv3482c 0.71 -0.6
3,901,877 - Rv3482c 0.71 +0.2
3,902,033 + -0.2
3,902,034 - +0.1
3,902,064 + -1.6
3,902,066 + -0.4
3,902,066 + +0.1
3,902,066 + +0.1
3,902,066 + +1.5
3,902,067 - -0.6
3,902,067 - +0.4
3,902,118 + +0.3

Or see this region's nucleotide sequence