Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3368c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3367 and Rv3368c are separated by 0 nucleotidesRv3368c and Rv3369 overlap by 2 nucleotidesRv3369 and Rv3370c are separated by 88 nucleotides Rv3367: Rv3367 - PE-PGRS family protein PE_PGRS51, at 3,778,568 to 3,780,334 Rv3367 Rv3368c: Rv3368c - Possible oxidoreductase, at 3,780,335 to 3,780,979 Rv3368c Rv3369: Rv3369 - Conserved protein, at 3,780,978 to 3,781,412 Rv3369 Rv3370c: Rv3370c - Probable DNA polymerase III (alpha chain) DnaE2 (DNA nucleotidyltransferase), at 3,781,501 to 3,784,740 Rv3370c Position (kb) 3780 3781Strain fitness (log2 ratio) -1 0 1at 3779.558 kb on - strand, within Rv3367at 3779.767 kb on + strand, within Rv3367at 3780.337 kb on - strandat 3780.408 kb on + strand, within Rv3368cat 3780.438 kb on + strand, within Rv3368cat 3780.439 kb on - strand, within Rv3368cat 3780.754 kb on - strand, within Rv3368cat 3781.113 kb on + strand, within Rv3369at 3781.114 kb on - strand, within Rv3369at 3781.141 kb on - strand, within Rv3369at 3781.296 kb on + strand, within Rv3369at 3781.308 kb on + strand, within Rv3369at 3781.309 kb on - strand, within Rv3369at 3781.309 kb on - strand, within Rv3369at 3781.356 kb on + strand, within Rv3369

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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3,779,558 - Rv3367 0.56 +0.3
3,779,767 + Rv3367 0.68 -0.3
3,780,337 - -0.7
3,780,408 + Rv3368c 0.11 +1.0
3,780,438 + Rv3368c 0.16 -0.3
3,780,439 - Rv3368c 0.16 +1.3
3,780,754 - Rv3368c 0.65 -0.2
3,781,113 + Rv3369 0.31 +0.4
3,781,114 - Rv3369 0.31 -0.4
3,781,141 - Rv3369 0.37 +0.9
3,781,296 + Rv3369 0.73 +1.4
3,781,308 + Rv3369 0.76 -0.4
3,781,309 - Rv3369 0.76 +0.4
3,781,309 - Rv3369 0.76 +0.6
3,781,356 + Rv3369 0.87 +0.2

Or see this region's nucleotide sequence