Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3312A

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with para-aminosalicylic 0.086 ug/mL
3,699,766	+		Rv3312c	0.39	+1.0
3,699,766	+		Rv3312c	0.39	-1.4
3,699,858	+		Rv3312c	0.49	-0.9
3,699,859	-		Rv3312c	0.49	-0.2
3,700,104	+		Rv3312c	0.76	+1.5
3,700,125	-		Rv3312c	0.78	-0.3
3,700,203	+		Rv3312c	0.86	-0.1
3,700,204	-		Rv3312c	0.86	+0.7
3,700,243	-				+0.1
3,700,348	+				+0.3
3,700,349	-				+0.0
3,700,349	-				-0.4
3,700,413	-				-0.7
3,700,413	-				+1.0
3,700,575	+				+0.3
3,700,641	+				-0.6
3,700,668	-				-1.6
3,700,669	+				-0.2
3,700,675	+				-0.4
3,700,707	-				-1.6
3,700,844	+		Rv3312A	0.45	+0.2
3,700,844	+		Rv3312A	0.45	+0.2
3,700,845	-		Rv3312A	0.45	-0.0
3,700,845	-		Rv3312A	0.45	-0.4
3,700,898	+		Rv3312A	0.62	+0.4
3,700,898	+		Rv3312A	0.62	+0.7
3,700,901	+		Rv3312A	0.63	+0.5
3,700,901	+		Rv3312A	0.63	+1.0
3,700,902	-		Rv3312A	0.63	+0.1
3,701,013	-				-0.4
3,701,059	-				+0.0
3,701,070	-				+1.2
3,701,234	+		Rv3313c	0.13	-0.6
3,701,324	+		Rv3313c	0.22	-0.3
3,701,419	+		Rv3313c	0.30	-0.4
3,701,419	+		Rv3313c	0.30	+0.1
3,701,881	-		Rv3313c	0.72	-0.1
3,701,932	-		Rv3313c	0.77	+0.2
3,701,985	+		Rv3313c	0.82	-0.1