Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv2005c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv2004c and Rv2005c are separated by 21 nucleotidesRv2005c and Rv2006 are separated by 118 nucleotides Rv2004c: Rv2004c - Conserved protein, at 2,249,478 to 2,250,974 Rv2004c Rv2005c: Rv2005c - Universal stress protein family protein, at 2,250,996 to 2,251,883 Rv2005c Rv2006: Rv2006 - Probable trehalose-6-phosphate phosphatase OtsB1 (trehalose-phosphatase) (TPP), at 2,252,002 to 2,255,985 Rv2006 Position (kb) 2250 2251 2252Strain fitness (log2 ratio) -1 0 1at 2250.140 kb on - strand, within Rv2004cat 2250.768 kb on - strand, within Rv2004cat 2251.578 kb on - strand, within Rv2005cat 2251.578 kb on - strand, within Rv2005cat 2251.578 kb on - strand, within Rv2005cat 2251.581 kb on + strand, within Rv2005cat 2251.597 kb on - strand, within Rv2005cat 2251.741 kb on - strand, within Rv2005cat 2251.741 kb on - strand, within Rv2005cat 2251.842 kb on + strandat 2251.877 kb on + strandat 2251.913 kb on - strandat 2251.913 kb on - strandat 2251.913 kb on - strandat 2252.150 kb on - strandat 2252.210 kb on - strandat 2252.810 kb on - strand, within Rv2006

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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2,250,140 - Rv2004c 0.44 -0.6
2,250,768 - Rv2004c 0.86 +0.5
2,251,578 - Rv2005c 0.66 +1.6
2,251,578 - Rv2005c 0.66 -0.1
2,251,578 - Rv2005c 0.66 +0.9
2,251,581 + Rv2005c 0.66 -0.3
2,251,597 - Rv2005c 0.68 +0.7
2,251,741 - Rv2005c 0.84 +0.7
2,251,741 - Rv2005c 0.84 -0.2
2,251,842 + -0.4
2,251,877 + -1.0
2,251,913 - -0.3
2,251,913 - +0.3
2,251,913 - -0.1
2,252,150 - +0.6
2,252,210 - -0.3
2,252,810 - Rv2006 0.20 -0.7

Or see this region's nucleotide sequence