Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1889c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with para-aminosalicylic 0.086 ug/mL
2,137,685	+		Rv1888c	0.30	-1.2
2,137,685	+		Rv1888c	0.30	-0.1
2,137,686	-		Rv1888c	0.30	-0.1
2,137,696	-		Rv1888c	0.32	-0.1
2,137,702	+		Rv1888c	0.33	-0.0
2,137,702	+		Rv1888c	0.33	-0.1
2,137,713	+		Rv1888c	0.35	+0.6
2,137,713	+		Rv1888c	0.35	+1.0
2,137,749	-		Rv1888c	0.41	-0.5
2,137,773	-		Rv1888c	0.45	-0.5
2,137,835	+		Rv1888c	0.56	-0.0
2,137,835	+		Rv1888c	0.56	-0.3
2,137,899	-		Rv1888c	0.68	-0.4
2,137,899	-		Rv1888c	0.68	+0.2
2,137,899	-		Rv1888c	0.68	+0.6
2,137,980	-		Rv1888c	0.82	+0.3
2,138,008	+		Rv1888c	0.87	+0.7
2,138,095	+				-0.8
2,138,095	+				-0.6
2,138,096	-				-0.4
2,138,096	-				+2.3
2,138,096	-				-0.3
2,138,175	+				-0.0
2,138,176	-				-0.0
2,138,202	+				-0.4
2,138,215	+				-0.1
2,138,215	+				-1.0
2,138,250	-				-0.4
2,138,349	+				+1.7
2,138,446	-				-0.2
2,138,446	-				-0.4
2,138,979	-		Rv1889c	0.89	+0.3
2,138,979	-		Rv1889c	0.89	+1.0
2,139,046	+				-1.0
2,139,046	+				+0.3
2,139,046	+				+0.2
2,139,047	-				+0.1
2,139,328	-		Rv1890c	0.41	-0.4
2,139,581	-		Rv1890c	0.83	-1.4
2,139,638	+				+1.2
2,139,699	+				-0.3
2,139,852	+		Rv1891	0.27	-0.1
2,139,853	-		Rv1891	0.27	-0.3
2,139,853	-		Rv1891	0.27	+0.2
2,139,853	-		Rv1891	0.27	-0.7
2,139,853	-		Rv1891	0.27	-1.4
2,139,951	-		Rv1891	0.51	-0.2
2,139,978	+		Rv1891	0.58	-0.8
2,140,001	-		Rv1891	0.64	+0.6
2,140,002	+		Rv1891	0.64	+0.4
2,140,002	+		Rv1891	0.64	+0.9
2,140,003	-		Rv1891	0.64	-0.2