Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1735c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1733c and Rv1734c are separated by 286 nucleotidesRv1734c and Rv1735c are separated by 274 nucleotidesRv1735c and Rv1736c are separated by 439 nucleotides Rv1733c: Rv1733c - Probable conserved transmembrane protein, at 1,959,855 to 1,960,487 Rv1733c Rv1734c: Rv1734c - Conserved hypothetical protein, at 1,960,774 to 1,961,016 Rv1734c Rv1735c: Rv1735c - Hypothetical membrane protein, at 1,961,291 to 1,961,788 Rv1735c Rv1736c: Rv1736c - Probable nitrate reductase NarX, at 1,962,228 to 1,964,186 Rv1736c Position (kb) 1961 1962Strain fitness (log2 ratio) -2 -1 0 1at 1960.605 kb on - strandat 1960.715 kb on + strandat 1960.716 kb on - strandat 1960.716 kb on - strandat 1960.719 kb on + strandat 1960.735 kb on + strandat 1960.735 kb on + strandat 1960.783 kb on + strandat 1961.120 kb on - strandat 1961.171 kb on - strandat 1961.292 kb on + strandat 1961.538 kb on + strand, within Rv1735cat 1961.539 kb on - strand, within Rv1735cat 1961.539 kb on - strand, within Rv1735cat 1961.596 kb on - strand, within Rv1735cat 1961.631 kb on - strand, within Rv1735cat 1961.832 kb on + strandat 1961.888 kb on + strandat 1961.889 kb on - strandat 1961.889 kb on - strandat 1961.899 kb on + strandat 1961.899 kb on + strandat 1961.969 kb on - strandat 1962.036 kb on - strandat 1962.077 kb on + strandat 1962.280 kb on + strandat 1962.281 kb on - strandat 1962.391 kb on + strandat 1962.394 kb on + strandat 1962.481 kb on + strand, within Rv1736cat 1962.481 kb on + strand, within Rv1736cat 1962.481 kb on + strand, within Rv1736cat 1962.556 kb on + strand, within Rv1736cat 1962.689 kb on - strand, within Rv1736cat 1962.689 kb on - strand, within Rv1736c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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1,960,605 - -0.0
1,960,715 + +0.0
1,960,716 - +0.8
1,960,716 - +0.0
1,960,719 + +1.3
1,960,735 + -0.7
1,960,735 + -1.1
1,960,783 + -0.1
1,961,120 - +0.3
1,961,171 - +0.2
1,961,292 + +0.4
1,961,538 + Rv1735c 0.50 +0.4
1,961,539 - Rv1735c 0.50 -0.3
1,961,539 - Rv1735c 0.50 -0.1
1,961,596 - Rv1735c 0.61 +0.9
1,961,631 - Rv1735c 0.68 +0.1
1,961,832 + +0.1
1,961,888 + -1.0
1,961,889 - +0.2
1,961,889 - +0.1
1,961,899 + -0.0
1,961,899 + -0.1
1,961,969 - +0.2
1,962,036 - +0.2
1,962,077 + -0.1
1,962,280 + +0.1
1,962,281 - -2.2
1,962,391 + -0.0
1,962,394 + -0.0
1,962,481 + Rv1736c 0.13 +0.4
1,962,481 + Rv1736c 0.13 -0.3
1,962,481 + Rv1736c 0.13 +0.2
1,962,556 + Rv1736c 0.17 -0.7
1,962,689 - Rv1736c 0.24 -0.5
1,962,689 - Rv1736c 0.24 -2.1

Or see this region's nucleotide sequence