Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1447c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1445c and Rv1446c overlap by 4 nucleotidesRv1446c and Rv1447c are separated by 52 nucleotidesRv1447c and Rv1448c overlap by 4 nucleotides Rv1445c: Rv1445c - Probable 6-phosphogluconolactonase DevB (6PGL), at 1,623,714 to 1,624,457 Rv1445c Rv1446c: Rv1446c - Putative OXPP cycle protein OpcA, at 1,624,454 to 1,625,365 Rv1446c Rv1447c: Rv1447c - Probable glucose-6-phosphate 1-dehydrogenase Zwf2 (G6PD), at 1,625,418 to 1,626,962 Rv1447c Rv1448c: Rv1448c - Probable transaldolase Tal, at 1,626,959 to 1,628,080 Rv1448c Position (kb) 1625 1626 1627Strain fitness (log2 ratio) -1 0 1at 1624.449 kb on - strandat 1624.449 kb on - strandat 1624.449 kb on - strandat 1624.830 kb on + strand, within Rv1446cat 1624.830 kb on + strand, within Rv1446cat 1624.830 kb on + strand, within Rv1446cat 1624.830 kb on + strand, within Rv1446cat 1625.420 kb on - strandat 1625.484 kb on - strandat 1625.484 kb on - strandat 1625.626 kb on + strand, within Rv1447cat 1625.882 kb on - strand, within Rv1447cat 1626.542 kb on - strand, within Rv1447cat 1626.542 kb on - strand, within Rv1447cat 1626.719 kb on - strand, within Rv1447cat 1626.719 kb on - strand, within Rv1447cat 1627.002 kb on - strandat 1627.002 kb on - strandat 1627.227 kb on + strand, within Rv1448cat 1627.228 kb on - strand, within Rv1448cat 1627.357 kb on - strand, within Rv1448cat 1627.854 kb on - strand, within Rv1448cat 1627.896 kb on + strand, within Rv1448c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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1,624,449 - -0.3
1,624,449 - -0.3
1,624,449 - -0.0
1,624,830 + Rv1446c 0.41 +0.7
1,624,830 + Rv1446c 0.41 -0.1
1,624,830 + Rv1446c 0.41 -0.3
1,624,830 + Rv1446c 0.41 +0.7
1,625,420 - +0.4
1,625,484 - -0.4
1,625,484 - +0.9
1,625,626 + Rv1447c 0.13 +1.1
1,625,882 - Rv1447c 0.30 -0.3
1,626,542 - Rv1447c 0.73 +0.7
1,626,542 - Rv1447c 0.73 +0.5
1,626,719 - Rv1447c 0.84 -0.1
1,626,719 - Rv1447c 0.84 +0.2
1,627,002 - +0.0
1,627,002 - -0.9
1,627,227 + Rv1448c 0.24 +0.3
1,627,228 - Rv1448c 0.24 +0.5
1,627,357 - Rv1448c 0.35 -0.6
1,627,854 - Rv1448c 0.80 -0.7
1,627,896 + Rv1448c 0.84 -0.3

Or see this region's nucleotide sequence