Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1068c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv1067c and Rv1068c are separated by 332 nucleotidesRv1068c and Rv1069c are separated by 361 nucleotides Rv1067c: Rv1067c - PE-PGRS family protein PE_PGRS19, at 1,188,421 to 1,190,424 Rv1067c Rv1068c: Rv1068c - PE-PGRS family protein PE_PGRS20, at 1,190,757 to 1,192,148 Rv1068c Rv1069c: Rv1069c - Conserved protein, at 1,192,510 to 1,194,273 Rv1069c Position (kb) 1190 1191 1192 1193Strain fitness (log2 ratio) -1 0 1 2at 1190.165 kb on + strand, within Rv1067cat 1190.166 kb on - strand, within Rv1067cat 1190.240 kb on + strandat 1190.241 kb on - strandat 1190.241 kb on - strandat 1190.694 kb on - strandat 1190.704 kb on - strandat 1190.725 kb on + strandat 1190.726 kb on - strandat 1190.759 kb on - strandat 1191.243 kb on - strand, within Rv1068cat 1191.889 kb on + strand, within Rv1068cat 1191.964 kb on + strand, within Rv1068cat 1192.141 kb on + strandat 1192.142 kb on - strandat 1192.142 kb on - strandat 1192.274 kb on - strandat 1192.411 kb on + strandat 1192.628 kb on + strandat 1192.672 kb on - strandat 1192.820 kb on + strand, within Rv1069cat 1192.821 kb on - strand, within Rv1069cat 1192.907 kb on + strand, within Rv1069c

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
remove
1,190,165 + Rv1067c 0.87 -0.5
1,190,166 - Rv1067c 0.87 +1.3
1,190,240 + +1.7
1,190,241 - -0.2
1,190,241 - +0.7
1,190,694 - +0.5
1,190,704 - -0.4
1,190,725 + -0.1
1,190,726 - -0.7
1,190,759 - -0.0
1,191,243 - Rv1068c 0.35 +0.9
1,191,889 + Rv1068c 0.81 -0.3
1,191,964 + Rv1068c 0.87 +1.8
1,192,141 + -0.3
1,192,142 - -0.3
1,192,142 - -0.3
1,192,274 - +0.1
1,192,411 + +0.7
1,192,628 + -0.2
1,192,672 - -0.2
1,192,820 + Rv1069c 0.18 -0.3
1,192,821 - Rv1069c 0.18 -0.6
1,192,907 + Rv1069c 0.23 -0.7

Or see this region's nucleotide sequence