Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv1032c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv1030 and Rv1031 overlap by 1 nucleotidesRv1031 and Rv1032c are separated by 3 nucleotidesRv1032c and Rv1033c are separated by 7 nucleotidesRv1033c and Rv1034c are separated by 181 nucleotides Rv1030: Rv1030 - Probable potassium-transporting P-type ATPase B chain KdpB (potassium-translocating ATPase B chain) (ATP phosphohydrolase [potassium-transporting] B chain) (potassium binding and translocating subunit B), at 1,153,724 to 1,155,853 Rv1030 Rv1031: Rv1031 - Probable potassium-transporting ATPase C chain KdpC (potassium-translocating ATPase C chain) (ATP phosphohydrolase [potassium-transporting] C chain) (potassium binding and translocating subunit C), at 1,155,853 to 1,156,422 Rv1031 Rv1032c: Rv1032c - Two component sensor histidine kinase TrcS, at 1,156,426 to 1,157,955 Rv1032c Rv1033c: Rv1033c - Two component transcriptional regulator TrcR, at 1,157,963 to 1,158,736 Rv1033c Rv1034c: Rv1034c - Probable transposase (fragment), at 1,158,918 to 1,159,307 Rv1034c Position (kb) 1156 1157 1158Strain fitness (log2 ratio) -2 -1 0 1 2at 1155.563 kb on + strand, within Rv1030at 1155.564 kb on - strand, within Rv1030at 1155.773 kb on + strandat 1155.773 kb on + strandat 1155.774 kb on - strandat 1155.774 kb on - strandat 1155.802 kb on + strandat 1156.045 kb on + strand, within Rv1031at 1156.046 kb on - strand, within Rv1031at 1156.082 kb on - strand, within Rv1031at 1156.302 kb on + strand, within Rv1031at 1156.303 kb on - strand, within Rv1031at 1156.303 kb on - strand, within Rv1031at 1156.737 kb on + strand, within Rv1032cat 1156.738 kb on - strand, within Rv1032cat 1156.759 kb on + strand, within Rv1032cat 1156.759 kb on + strand, within Rv1032cat 1156.916 kb on - strand, within Rv1032cat 1157.227 kb on - strand, within Rv1032cat 1157.227 kb on - strand, within Rv1032cat 1157.271 kb on + strand, within Rv1032cat 1157.272 kb on - strand, within Rv1032cat 1157.443 kb on + strand, within Rv1032cat 1157.747 kb on + strand, within Rv1032cat 1157.747 kb on + strand, within Rv1032cat 1157.748 kb on - strand, within Rv1032cat 1157.807 kb on + strandat 1157.807 kb on + strandat 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.985 kb on + strandat 1157.986 kb on - strandat 1157.986 kb on - strandat 1157.986 kb on - strandat 1158.005 kb on - strandat 1158.048 kb on + strand, within Rv1033cat 1158.049 kb on - strand, within Rv1033cat 1158.056 kb on - strand, within Rv1033cat 1158.056 kb on - strand, within Rv1033cat 1158.056 kb on - strand, within Rv1033cat 1158.057 kb on + strand, within Rv1033cat 1158.057 kb on + strand, within Rv1033cat 1158.058 kb on - strand, within Rv1033cat 1158.058 kb on - strand, within Rv1033cat 1158.058 kb on - strand, within Rv1033cat 1158.093 kb on + strand, within Rv1033cat 1158.094 kb on - strand, within Rv1033cat 1158.200 kb on - strand, within Rv1033cat 1158.213 kb on - strand, within Rv1033cat 1158.238 kb on + strand, within Rv1033cat 1158.239 kb on - strand, within Rv1033cat 1158.239 kb on - strand, within Rv1033cat 1158.239 kb on - strand, within Rv1033cat 1158.351 kb on + strand, within Rv1033cat 1158.351 kb on + strand, within Rv1033cat 1158.351 kb on + strand, within Rv1033cat 1158.429 kb on + strand, within Rv1033cat 1158.579 kb on + strand, within Rv1033cat 1158.580 kb on - strand, within Rv1033cat 1158.718 kb on - strandat 1158.745 kb on - strandat 1158.745 kb on - strandat 1158.813 kb on + strandat 1158.896 kb on + strand

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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1,155,563 + Rv1030 0.86 -0.1
1,155,564 - Rv1030 0.86 +0.7
1,155,773 + -0.3
1,155,773 + +0.0
1,155,774 - -0.4
1,155,774 - +0.5
1,155,802 + +0.1
1,156,045 + Rv1031 0.34 +1.0
1,156,046 - Rv1031 0.34 -0.4
1,156,082 - Rv1031 0.40 +0.3
1,156,302 + Rv1031 0.79 -0.7
1,156,303 - Rv1031 0.79 +0.3
1,156,303 - Rv1031 0.79 +0.5
1,156,737 + Rv1032c 0.20 -0.3
1,156,738 - Rv1032c 0.20 -0.0
1,156,759 + Rv1032c 0.22 -0.5
1,156,759 + Rv1032c 0.22 -0.2
1,156,916 - Rv1032c 0.32 -0.1
1,157,227 - Rv1032c 0.52 +0.7
1,157,227 - Rv1032c 0.52 -0.6
1,157,271 + Rv1032c 0.55 +0.7
1,157,272 - Rv1032c 0.55 +0.7
1,157,443 + Rv1032c 0.66 -0.5
1,157,747 + Rv1032c 0.86 -0.0
1,157,747 + Rv1032c 0.86 -0.2
1,157,748 - Rv1032c 0.86 -0.2
1,157,807 + -0.1
1,157,807 + -0.3
1,157,985 + -0.5
1,157,985 + -0.3
1,157,985 + -0.5
1,157,985 + -0.5
1,157,985 + -0.8
1,157,986 - -0.3
1,157,986 - -0.1
1,157,986 - -1.5
1,158,005 - +0.7
1,158,048 + Rv1033c 0.11 +1.4
1,158,049 - Rv1033c 0.11 +1.7
1,158,056 - Rv1033c 0.12 +2.1
1,158,056 - Rv1033c 0.12 -0.5
1,158,056 - Rv1033c 0.12 -0.1
1,158,057 + Rv1033c 0.12 -1.0
1,158,057 + Rv1033c 0.12 -0.1
1,158,058 - Rv1033c 0.12 +2.0
1,158,058 - Rv1033c 0.12 +0.3
1,158,058 - Rv1033c 0.12 +0.2
1,158,093 + Rv1033c 0.17 -1.1
1,158,094 - Rv1033c 0.17 +0.1
1,158,200 - Rv1033c 0.31 -0.3
1,158,213 - Rv1033c 0.32 -0.1
1,158,238 + Rv1033c 0.36 +1.3
1,158,239 - Rv1033c 0.36 -0.2
1,158,239 - Rv1033c 0.36 +0.3
1,158,239 - Rv1033c 0.36 -0.2
1,158,351 + Rv1033c 0.50 +0.7
1,158,351 + Rv1033c 0.50 -1.6
1,158,351 + Rv1033c 0.50 +0.7
1,158,429 + Rv1033c 0.60 -0.7
1,158,579 + Rv1033c 0.80 -2.0
1,158,580 - Rv1033c 0.80 +0.4
1,158,718 - -0.3
1,158,745 - -0.4
1,158,745 - -0.6
1,158,813 + -0.0
1,158,896 + -0.6

Or see this region's nucleotide sequence