Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0574c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0573c and Rv0574c are separated by 9 nucleotidesRv0574c and Rv0575c are separated by 184 nucleotides Rv0573c: Rv0573c - Nicotinic acid phosphoribosyltransferase PncB2, at 665,851 to 667,242 Rv0573c Rv0574c: Rv0574c - Conserved hypothetical protein, at 667,252 to 668,394 Rv0574c Rv0575c: Rv0575c - Possible oxidoreductase, at 668,579 to 669,745 Rv0575c Position (kb) 667 668 669Strain fitness (log2 ratio) -2 -1 0 1 2 3at 666.260 kb on + strand, within Rv0573cat 666.261 kb on - strand, within Rv0573cat 666.539 kb on - strand, within Rv0573cat 666.548 kb on + strand, within Rv0573cat 666.549 kb on - strand, within Rv0573cat 666.549 kb on - strand, within Rv0573cat 666.717 kb on - strand, within Rv0573cat 667.028 kb on + strand, within Rv0573cat 667.104 kb on - strandat 667.254 kb on - strandat 667.267 kb on + strandat 667.472 kb on + strand, within Rv0574cat 667.473 kb on - strand, within Rv0574cat 667.473 kb on - strand, within Rv0574cat 667.473 kb on - strand, within Rv0574cat 667.524 kb on - strand, within Rv0574cat 667.572 kb on - strand, within Rv0574cat 667.572 kb on - strand, within Rv0574cat 667.572 kb on - strand, within Rv0574cat 667.572 kb on - strand, within Rv0574cat 667.573 kb on + strand, within Rv0574cat 667.573 kb on + strand, within Rv0574cat 667.574 kb on - strand, within Rv0574cat 667.574 kb on - strand, within Rv0574cat 667.676 kb on + strand, within Rv0574cat 667.677 kb on - strand, within Rv0574cat 667.709 kb on - strand, within Rv0574cat 668.087 kb on + strand, within Rv0574cat 668.261 kb on + strand, within Rv0574cat 668.280 kb on + strandat 668.282 kb on + strandat 668.282 kb on + strandat 668.282 kb on + strandat 668.283 kb on - strandat 668.440 kb on - strandat 668.446 kb on + strandat 668.447 kb on - strandat 668.447 kb on - strandat 668.447 kb on - strandat 668.461 kb on - strandat 668.548 kb on + strandat 668.549 kb on - strandat 668.835 kb on + strand, within Rv0575cat 668.835 kb on + strand, within Rv0575cat 668.881 kb on - strand, within Rv0575cat 669.154 kb on - strand, within Rv0575cat 669.154 kb on - strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.162 kb on + strand, within Rv0575cat 669.226 kb on - strand, within Rv0575c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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666,260 + Rv0573c 0.29 +1.0
666,261 - Rv0573c 0.29 -1.5
666,539 - Rv0573c 0.49 +1.5
666,548 + Rv0573c 0.50 +0.3
666,549 - Rv0573c 0.50 -0.5
666,549 - Rv0573c 0.50 +0.3
666,717 - Rv0573c 0.62 -0.8
667,028 + Rv0573c 0.85 -1.3
667,104 - +0.1
667,254 - +0.6
667,267 + +0.7
667,472 + Rv0574c 0.19 +0.7
667,473 - Rv0574c 0.19 +3.7
667,473 - Rv0574c 0.19 +0.4
667,473 - Rv0574c 0.19 +1.7
667,524 - Rv0574c 0.24 -0.4
667,572 - Rv0574c 0.28 -0.3
667,572 - Rv0574c 0.28 +0.7
667,572 - Rv0574c 0.28 -0.4
667,572 - Rv0574c 0.28 +0.3
667,573 + Rv0574c 0.28 +0.4
667,573 + Rv0574c 0.28 +0.7
667,574 - Rv0574c 0.28 -0.6
667,574 - Rv0574c 0.28 +1.2
667,676 + Rv0574c 0.37 -1.8
667,677 - Rv0574c 0.37 +0.1
667,709 - Rv0574c 0.40 +0.4
668,087 + Rv0574c 0.73 -0.0
668,261 + Rv0574c 0.88 +0.2
668,280 + -1.6
668,282 + -0.3
668,282 + +0.3
668,282 + +0.7
668,283 - -0.3
668,440 - -0.3
668,446 + -0.5
668,447 - +0.3
668,447 - -0.2
668,447 - -0.3
668,461 - -0.1
668,548 + -0.9
668,549 - +0.1
668,835 + Rv0575c 0.22 +0.2
668,835 + Rv0575c 0.22 +0.1
668,881 - Rv0575c 0.26 +0.1
669,154 - Rv0575c 0.49 +0.5
669,154 - Rv0575c 0.49 -0.8
669,162 + Rv0575c 0.50 +1.1
669,162 + Rv0575c 0.50 -0.3
669,162 + Rv0575c 0.50 +0.3
669,162 + Rv0575c 0.50 -0.3
669,226 - Rv0575c 0.55 +0.2

Or see this region's nucleotide sequence