Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0277c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv0276 and Rv0277c are separated by 39 nucleotidesRv0277c and Rv0277A are separated by 23 nucleotidesRv0277A and Rv0278c are separated by 19 nucleotides Rv0276: Rv0276 - Conserved hypothetical protein, at 331,748 to 332,668 Rv0276 Rv0277c: Rv0277c - Possible toxin VapC25. Contains PIN domain., at 332,708 to 333,136 Rv0277c Rv0277A: Rv0277A - Possible antitoxin VapB25, at 333,160 to 333,417 Rv0277A Rv0278c: Rv0278c - PE-PGRS family protein PE_PGRS3, at 333,437 to 336,310 Rv0278c Position (kb) 332 333 334Strain fitness (log2 ratio) -1 0 1at 332.017 kb on + strand, within Rv0276at 332.021 kb on + strand, within Rv0276at 332.022 kb on - strand, within Rv0276at 332.129 kb on + strand, within Rv0276at 332.152 kb on - strand, within Rv0276at 332.177 kb on + strand, within Rv0276at 332.180 kb on - strand, within Rv0276at 332.378 kb on + strand, within Rv0276at 332.379 kb on - strand, within Rv0276at 332.666 kb on + strandat 332.710 kb on - strandat 332.725 kb on + strandat 332.725 kb on + strandat 332.725 kb on + strandat 332.726 kb on - strandat 333.011 kb on + strand, within Rv0277cat 333.011 kb on + strand, within Rv0277cat 333.012 kb on - strand, within Rv0277cat 333.012 kb on - strand, within Rv0277cat 333.012 kb on - strand, within Rv0277cat 333.012 kb on - strand, within Rv0277cat 333.141 kb on + strandat 333.141 kb on + strandat 333.141 kb on + strandat 333.142 kb on - strandat 333.142 kb on - strandat 333.214 kb on - strand, within Rv0277Aat 333.224 kb on - strand, within Rv0277Aat 333.224 kb on - strand, within Rv0277Aat 333.224 kb on - strand, within Rv0277Aat 333.232 kb on - strand, within Rv0277Aat 333.232 kb on - strand, within Rv0277Aat 333.386 kb on - strand, within Rv0277Aat 333.430 kb on - strandat 333.438 kb on + strandat 333.439 kb on - strandat 333.503 kb on + strandat 333.503 kb on + strandat 333.905 kb on + strand, within Rv0278cat 333.905 kb on + strand, within Rv0278cat 333.906 kb on - strand, within Rv0278cat 333.999 kb on - strand, within Rv0278cat 333.999 kb on - strand, within Rv0278cat 333.999 kb on - strand, within Rv0278c

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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332,017 + Rv0276 0.29 +0.4
332,021 + Rv0276 0.30 +0.6
332,022 - Rv0276 0.30 +0.7
332,129 + Rv0276 0.41 -0.3
332,152 - Rv0276 0.44 +0.8
332,177 + Rv0276 0.47 +0.7
332,180 - Rv0276 0.47 -0.6
332,378 + Rv0276 0.68 -0.1
332,379 - Rv0276 0.69 +0.3
332,666 + +0.4
332,710 - +0.0
332,725 + +0.9
332,725 + -0.6
332,725 + -0.1
332,726 - +0.2
333,011 + Rv0277c 0.71 +0.8
333,011 + Rv0277c 0.71 +0.5
333,012 - Rv0277c 0.71 -1.6
333,012 - Rv0277c 0.71 +0.1
333,012 - Rv0277c 0.71 +0.2
333,012 - Rv0277c 0.71 +0.6
333,141 + +0.6
333,141 + +0.0
333,141 + +0.5
333,142 - +0.3
333,142 - -1.1
333,214 - Rv0277A 0.21 +0.4
333,224 - Rv0277A 0.25 -0.9
333,224 - Rv0277A 0.25 -0.6
333,224 - Rv0277A 0.25 -0.6
333,232 - Rv0277A 0.28 -1.1
333,232 - Rv0277A 0.28 +0.4
333,386 - Rv0277A 0.88 -0.6
333,430 - +0.2
333,438 + -0.2
333,439 - +0.1
333,503 + -0.1
333,503 + -0.7
333,905 + Rv0278c 0.16 +0.2
333,905 + Rv0278c 0.16 -0.4
333,906 - Rv0278c 0.16 -0.7
333,999 - Rv0278c 0.20 -0.3
333,999 - Rv0278c 0.20 +0.1
333,999 - Rv0278c 0.20 +1.0

Or see this region's nucleotide sequence