Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv0114

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

Add experiment(s):

Zoom: Pan:

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

download SVG
500 ntRv0112 and Rv0113 are separated by 73 nucleotidesRv0113 and Rv0114 are separated by 31 nucleotidesRv0114 and Rv0115 overlap by 1 nucleotides Rv0112: Rv0112 - Possible GDP-mannose 4,6-dehydratase Gca (GDP-D-mannose dehydratase), at 136,289 to 137,245 Rv0112 Rv0113: Rv0113 - Probable sedoheptulose-7-phosphate isomerase GmhA (phosphoheptose isomerase), at 137,319 to 137,909 Rv0113 Rv0114: Rv0114 - Possible D-alpha,beta-D-heptose-1,7-biphosphate phosphatase GmhB (D-glycero-D-manno-heptose 7-phosphate kinase), at 137,941 to 138,513 Rv0114 Rv0115: Rv0115 - Possible D-alpha-D-heptose-7-phosphate kinase HddA, at 138,513 to 139,673 Rv0115 Position (kb) 137 138 139Strain fitness (log2 ratio) -1 0 1 2at 137.043 kb on + strand, within Rv0112at 137.044 kb on - strand, within Rv0112at 137.123 kb on + strand, within Rv0112at 137.151 kb on + strandat 137.588 kb on - strand, within Rv0113at 137.607 kb on + strand, within Rv0113at 138.023 kb on - strand, within Rv0114at 138.100 kb on + strand, within Rv0114at 138.100 kb on + strand, within Rv0114at 138.101 kb on - strand, within Rv0114at 138.170 kb on + strand, within Rv0114at 138.170 kb on + strand, within Rv0114at 138.170 kb on + strand, within Rv0114at 138.215 kb on + strand, within Rv0114at 138.215 kb on + strand, within Rv0114at 138.215 kb on + strand, within Rv0114at 138.216 kb on - strand, within Rv0114at 138.267 kb on + strand, within Rv0114at 138.630 kb on + strand, within Rv0115at 138.631 kb on - strand, within Rv0115at 138.636 kb on + strand, within Rv0115at 138.797 kb on + strand, within Rv0115at 138.798 kb on - strand, within Rv0115at 138.798 kb on - strand, within Rv0115at 138.928 kb on - strand, within Rv0115at 138.928 kb on - strand, within Rv0115at 139.119 kb on + strand, within Rv0115at 139.119 kb on + strand, within Rv0115at 139.120 kb on - strand, within Rv0115at 139.267 kb on + strand, within Rv0115at 139.268 kb on - strand, within Rv0115at 139.452 kb on - strand, within Rv0115at 139.452 kb on - strand, within Rv0115at 139.512 kb on - strand, within Rv0115

download strain data

Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
remove
137,043 + Rv0112 0.79 +0.1
137,044 - Rv0112 0.79 -1.5
137,123 + Rv0112 0.87 +0.2
137,151 + +0.7
137,588 - Rv0113 0.46 +1.7
137,607 + Rv0113 0.49 +0.3
138,023 - Rv0114 0.14 +0.1
138,100 + Rv0114 0.28 -0.5
138,100 + Rv0114 0.28 -0.4
138,101 - Rv0114 0.28 -0.1
138,170 + Rv0114 0.40 -0.1
138,170 + Rv0114 0.40 -0.6
138,170 + Rv0114 0.40 +1.8
138,215 + Rv0114 0.48 +0.5
138,215 + Rv0114 0.48 +0.5
138,215 + Rv0114 0.48 +0.3
138,216 - Rv0114 0.48 -1.3
138,267 + Rv0114 0.57 -0.1
138,630 + Rv0115 0.10 -1.3
138,631 - Rv0115 0.10 -0.3
138,636 + Rv0115 0.11 -0.2
138,797 + Rv0115 0.24 +0.0
138,798 - Rv0115 0.25 -0.8
138,798 - Rv0115 0.25 +0.3
138,928 - Rv0115 0.36 +2.3
138,928 - Rv0115 0.36 -0.6
139,119 + Rv0115 0.52 -0.1
139,119 + Rv0115 0.52 -1.1
139,120 - Rv0115 0.52 +1.0
139,267 + Rv0115 0.65 +0.1
139,268 - Rv0115 0.65 -0.0
139,452 - Rv0115 0.81 +1.7
139,452 - Rv0115 0.81 +0.3
139,512 - Rv0115 0.86 +0.6

Or see this region's nucleotide sequence