Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3724B

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with para-aminosalicylic 0.086 ug/mL
4,168,887	+		Rv3723	0.46	-0.3
4,168,887	+		Rv3723	0.46	-0.2
4,168,888	-		Rv3723	0.46	+0.8
4,168,932	+		Rv3723	0.52	-0.6
4,169,129	-		Rv3723	0.78	-0.2
4,169,129	-		Rv3723	0.78	-1.2
4,169,129	-		Rv3723	0.78	+0.2
4,169,299	-				-0.6
4,169,317	+				-0.2
4,169,429	+				+0.6
4,169,429	+				-0.4
4,169,429	+				-0.1
4,169,430	-				-0.1
4,169,540	+		Rv3724A	0.30	+0.8
4,169,699	+				-0.8
4,169,749	+		Rv3724B	0.25	+0.1
4,169,788	+		Rv3724B	0.32	+0.0
4,169,788	+		Rv3724B	0.32	-0.1
4,169,841	-		Rv3724B	0.42	+0.9
4,169,868	-		Rv3724B	0.46	+0.0
4,169,937	+		Rv3724B	0.59	-0.3
4,170,033	-		Rv3724B	0.76	+0.9
4,170,033	-		Rv3724B	0.76	-1.3
4,170,113	+				-0.2
4,170,114	-				-0.0
4,170,114	-				-0.4
4,170,132	+				-0.3
4,170,132	+				-0.0
4,170,132	+				-0.3
4,170,133	-				-0.9
4,170,133	-				-0.3
4,170,133	-				+0.4
4,170,168	-				+2.0
4,170,168	-				-0.2
4,170,396	-		Rv3725	0.20	-0.3
4,170,396	-		Rv3725	0.20	+0.2
4,170,502	-		Rv3725	0.31	-0.4
4,170,727	+		Rv3725	0.55	+1.0
4,170,727	+		Rv3725	0.55	-1.3
4,170,728	-		Rv3725	0.55	-0.2
4,170,728	-		Rv3725	0.55	+0.5
4,170,911	-		Rv3725	0.75	+0.0
4,171,050	+		Rv3725	0.90	-0.4
4,171,064	+				+0.3
4,171,085	+				-0.1
4,171,085	+				+1.0
4,171,086	-				-1.0
4,171,086	-				-0.4
4,171,086	-				-0.6
4,171,092	+				-0.2
4,171,092	+				-0.0
4,171,092	+				-0.9
4,171,093	-				-0.6
4,171,093	-				-0.4
4,171,093	-				+0.2
4,171,093	-				-0.3
4,171,093	-				-0.2
4,171,095	+				-1.0
4,171,095	+				-0.1
4,171,095	+				+0.4
4,171,096	-				+0.1
4,171,096	-				+0.3
4,171,096	-				-0.3
4,171,141	+				-0.4
4,171,141	+				+0.1
4,171,141	+				+0.3
4,171,142	-				+0.4
4,171,142	-				-0.8