Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3560c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

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Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

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500 ntRv3558 and Rv3559c are separated by 8 nucleotidesRv3559c and Rv3560c overlap by 4 nucleotidesRv3560c and Rv3561 are separated by 47 nucleotides Rv3558: Rv3558 - PPE family protein PPE64, at 3,997,980 to 3,999,638 Rv3558 Rv3559c: Rv3559c - Probable oxidoreductase, at 3,999,647 to 4,000,435 Rv3559c Rv3560c: Rv3560c - Probable acyl-CoA dehydrogenase FadE30, at 4,000,432 to 4,001,589 Rv3560c Rv3561: Rv3561 - Probable fatty-acid-CoA ligase FadD3 (fatty-acid-CoA synthetase) (fatty-acid-CoA synthase), at 4,001,637 to 4,003,160 Rv3561 Position (kb) 4000 4001 4002Strain fitness (log2 ratio) -2 -1 0 1 2at 3999.445 kb on + strand, within Rv3558at 3999.585 kb on - strandat 4000.012 kb on - strand, within Rv3559cat 4000.012 kb on - strand, within Rv3559cat 4000.535 kb on + strandat 4000.535 kb on + strandat 4000.536 kb on - strandat 4000.536 kb on - strandat 4000.536 kb on - strandat 4000.707 kb on - strand, within Rv3560cat 4001.031 kb on - strand, within Rv3560cat 4001.132 kb on - strand, within Rv3560cat 4001.208 kb on - strand, within Rv3560cat 4001.352 kb on - strand, within Rv3560cat 4001.352 kb on - strand, within Rv3560cat 4001.352 kb on - strand, within Rv3560cat 4001.512 kb on - strandat 4001.512 kb on - strandat 4001.512 kb on - strandat 4001.596 kb on + strandat 4001.904 kb on + strand, within Rv3561at 4001.905 kb on - strand, within Rv3561at 4002.273 kb on + strand, within Rv3561at 4002.274 kb on - strand, within Rv3561at 4002.274 kb on - strand, within Rv3561at 4002.309 kb on + strand, within Rv3561

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Per-strain Table

Position Strand Gene LocusTag Fraction 7H9 with para-aminosalicylic 0.086 ug/mL
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3,999,445 + Rv3558 0.88 +0.1
3,999,585 - -0.5
4,000,012 - Rv3559c 0.46 -0.4
4,000,012 - Rv3559c 0.46 -0.0
4,000,535 + -2.2
4,000,535 + -0.5
4,000,536 - -1.2
4,000,536 - +0.3
4,000,536 - -0.2
4,000,707 - Rv3560c 0.24 +0.2
4,001,031 - Rv3560c 0.52 -0.3
4,001,132 - Rv3560c 0.60 +1.3
4,001,208 - Rv3560c 0.67 -1.0
4,001,352 - Rv3560c 0.79 -0.6
4,001,352 - Rv3560c 0.79 +0.7
4,001,352 - Rv3560c 0.79 -1.0
4,001,512 - -0.1
4,001,512 - -0.7
4,001,512 - -0.5
4,001,596 + -2.0
4,001,904 + Rv3561 0.18 -0.4
4,001,905 - Rv3561 0.18 -0.6
4,002,273 + Rv3561 0.42 -0.1
4,002,274 - Rv3561 0.42 -0.5
4,002,274 - Rv3561 0.42 +0.7
4,002,309 + Rv3561 0.44 +1.9

Or see this region's nucleotide sequence