Strain Fitness in Mycobacterium tuberculosis H37Rv around Rv3249c

Experiment: 7H9 with para-aminosalicylic 0.086 ug/mL

Only strains with sufficient reads to estimate fitness are shown, but the strain fitness values are still rather noisy and may be biased towards zero. Strains near the edge of a gene are not shown as being associated with that gene (they are in grey). Strains in the central 10-90% of a gene are color coded by the insertion's strand. Usually, "+" means that the selectable marker is encoded on the forward strand, i.e., transcribed rightward.

Per-strain Table

Position	Strand	Gene	LocusTag	Fraction	7H9 with para-aminosalicylic 0.086 ug/mL
3,629,699	-				-0.1
3,629,703	+				+1.3
3,629,708	-				+0.7
3,629,708	-				-0.7
3,629,708	-				+0.2
3,629,708	-				-0.8
3,629,795	-				-0.8
3,629,795	-				+0.7
3,629,922	+		Rv3249c	0.27	+0.3
3,630,142	+		Rv3249c	0.61	+0.4
3,630,369	+				-0.5
3,630,370	-				-0.5
3,630,370	-				-0.0
3,630,557	-				-0.2
3,630,568	+				-0.1
3,630,569	-				-0.8
3,630,569	-				-0.3
3,630,569	-				+1.0
3,630,572	+				-0.3
3,630,572	+				+0.3
3,630,573	-				+0.5
3,630,573	-				-0.3
3,630,580	+				-0.0
3,630,580	+				-0.0
3,630,580	+				-0.5
3,630,580	+				-0.6
3,630,581	-				-0.7
3,630,581	-				-0.1
3,630,581	-				-0.8
3,630,707	+		Rv3251c	0.81	+0.3
3,630,708	-		Rv3251c	0.82	-0.2
3,630,818	-				+0.7
3,630,843	+				-0.3
3,630,844	-				+1.3
3,630,844	-				-0.1
3,630,844	-				-0.4
3,630,893	-		Rv3252c	0.12	+0.7
3,630,988	+		Rv3252c	0.20	-0.2
3,631,051	+		Rv3252c	0.25	-0.0
3,631,078	-		Rv3252c	0.27	-0.9
3,631,088	-		Rv3252c	0.28	+0.3
3,631,099	+		Rv3252c	0.29	-2.2
3,631,099	+		Rv3252c	0.29	-0.2
3,631,099	+		Rv3252c	0.29	-0.0
3,631,100	-		Rv3252c	0.29	-0.7
3,631,113	+		Rv3252c	0.30	+0.3
3,631,241	-		Rv3252c	0.40	-0.2